FY 2025 Total Revenue of
FY 2025 ASCENIV Revenue Grew to
FY 2025 Adjusted Net Income(1) of
FY 2025 Adjusted EBITDA(2) of
Incoming CFO Appointment Expected to Further Enhance Financial Strategy, Working Capital Execution and Capital Allocation Discipline
Advancing SG-001 Pipeline Program with Anticipated FDA Pre-IND Meeting in 2026; Potential Accelerated Path to Registrational Trial
Ongoing Share Repurchases and Capital Structure to Increase Stockholder Value
Reiterating Previously Provided 2026-2029 Financial Guidance
“2025 marked a year of disciplined execution, record performance and meaningful strategic progress for ADMA, and we are entering 2026 with significant momentum,” said
“We exited 2025 having completed several foundational, value-enhancing initiatives,”
Financial Guidance and Long-Term Growth Outlook
- FY 2026 total revenue expected to exceed
$635 million - FY 2026 Adjusted Net Income expected to exceed
$255 million - FY 2026 Adjusted EBITDA expected to exceed
$360 million - FY 2027 total revenue expected to exceed
$775 million - FY 2027 Adjusted Net Income expected to exceed
$315 million - FY 2027 Adjusted EBITDA expected to exceed
$455 million - Targeting greater than
$1.1 billion in total annual revenue in fiscal year 2029, translating to at least$700 million in Adjusted EBITDA
Commercial and Operational Execution Driving Margin Growth
- Appointment of Incoming Chief Financial Officer and Treasurer to Further Enhance Financial Strategy and Capital Allocation Discipline. ADMA announced the retirement of
Brad Tade as Chief Financial Officer and Treasurer following a successful tenure that supported the Company’s transformation to sustained profitability.Terry Kohler has been appointed as the Company’s new Chief Financial Officer and Treasurer, bringing extensive public company experience and expertise in working capital optimization, cash generation, capital markets strategy, and disciplined financial execution. As ADMA enters an expected transformative year in anticipated margin growth and increasing cash flow, this transition is expected to continue financial strategy, reinforce operating rigor, and support long-term stockholder value creation.Mr. Tade will serve in a consulting capacity to support a structured transition throughJuly 2026 , ensuring continuity.Mr. Kohler most recently served as CFO ofOptiNose, Inc. , where he helped guide the company through its acquisition byParatek Pharmaceuticals , and also previously served as CFO of Verrica Pharmaceuticals.Mr. Kohler previously held senior financial leadership roles atEndo International , including Treasurer and Head of Corporate Development, as well as Vice President ofU.S. Branded andSpecialty Pharmaceuticals .
- Commercial and Operational Execution Driving Margin Growth. ASCENIV utilization reached record highs exiting 2025, with full-year revenues increasing 51% year-over-year to
$363 million , driven by robust demand and expanding prescriber adoption. This momentum is expected to continue into 2026, driven by broader payer coverage, a growing body of real-world evidence, and increasing confidence in long-term supply continuity. With ASCENIV still forecasted to be in the early stages of penetrating its total addressable market, the product is driven by a differentiated, patented supply and manufacturing platform. Year-end 2025 performance and 2026 year-to-date trends provide high confidence in sustained demand growth throughout 2026 and beyond. - Real-World Data Publications Reinforcing ASCENIV Differentiation and Adoption. Multiple independent 2025 real-world datasets further validated ASCENIV’s differentiated profile. Statistically significant infection reductions observed in investigator-initiated analyses continue to enhance physician confidence, support payer engagement, and expand medical education initiatives—key drivers of strong 2026 utilization.
- A peer-reviewed study (Tan et al., ACAAI 2025; Clinical Immunology) demonstrated meaningful reductions in infections and hospitalizations in patients with primary or secondary immunodeficiencies who failed prior IVIG and transitioned to ASCENIV. Seventy-one percent of patients improved clinically, with the greatest impact observed within the first six months of treatment.
- Durable Payer Coverage Supporting Consistent Patient Access. ASCENIV and BIVIGAM maintain broad and improving coverage across both commercial plans and Medicare Part B government reimbursement channels. These partnerships reinforce favorable positioning, consistent patient access, and strong provider confidence.
- Strategic Plasma Network Actions Improve Supply Visibility and Capital Efficiency. In
December 2025 , ADMA reached an agreement to divest three plasma centers for$12 million while retaining seven plasma collection centers. Long-term supply agreements with the purchaser maintains diversity of ADMA’s high-titer plasma sources, and the Company remains on track to close the transaction in the first quarter of 2026. Third-party suppliers exceeded expectations in 2025, and new contracts now provide access to 280+ plasma collection centers—expected to materially improve ASCENIV’s long-term supply opportunity. We believe, together, these actions create a more flexible, capital-efficient supply model expected to deliver accretive cost savings beginning in 2026, expand total production capability, and support durable supply through the late 2030s and beyond. - Disciplined Commercial Execution Driving Operating Leverage. Focused field execution, expanded medical education, and recently commenced direct-to-patient initiatives are expected to accelerate demand utilization while maintaining cost discipline. This execution positions ADMA for continued operating leverage and margin growth throughout 2026 and beyond.
- Improve Balance Sheet and Forecasted Cash Generation Growth. ADMA exited 2025 with approximately
$88 million in cash, largely excluding proceeds from the plasma center divestiture, which remains on track to close in the first quarter of 2026. During 2026, ADMA expects strong cash generation, strategy-driven cost savings, and improved financial flexibility to support growth initiatives, balance sheet optimization, and stockholder returns. - Expanding Distribution Footprint to Broaden Reach and Upgrade Working Capital Efficiency. In the fourth quarter of 2025, ADMA executed a new authorized distribution agreement with McKesson Specialty for ASCENIV and BIVIGAM, expanding access to additional sites of care and patient populations. As this new partnership ramps up, the Company expects the expanded distribution platform to further optimize working capital dynamics, including improved accounts receivable performance and enhanced cash conversion. ADMA continues constructive discussions to further diversify distribution in 2026, supporting sustained product growth and operational efficiency.
- Yield-Enhanced Production in Full Commercial Operation; 2026 a Step-Change Year. Yield-enhanced production has successfully transitioned into routine commercial execution in 2025 with continued FDA lot releases. Fiscal 2026 represents the first full year of yield-enhanced output, positioning ADMA for sustained gross margin growth and anticipated material increases in earnings power.
- Pipeline Optionality Enrich Long-Term Upside. ADMA advanced SG-001 preclinical development in 2025 and plans to submit a pre-Investigational New Drug (IND) meeting package to the FDA in 2026, potentially enabling direct progression into a registrational trial. SG-001 is designed to deliver broad pneumococcal serotype coverage, including prevalent and emerging serotypes not fully addressed by currently available vaccines, consistent with prior Company communications. Management continues to view SG-001 as a potential $300–$500 million peak annual revenue opportunity, reinforcing long-term pipeline value.
Full Year 2025 Financial Results:
Total revenue for the year ended
Gross profit for the year ended
Research and development expenses for the year ended
Selling, general and administrative expenses for the year ended
GAAP net income for the year ended
Adjusted net income for the year ended
Adjusted EBITDA for the year ended
Fourth Quarter 2025 Financial Results:
Total revenue for the quarter ended
Gross profit for the quarter ended
GAAP net income for the quarter ended
Adjusted net income for the quarter ended
Adjusted EBITDA for the quarter ended
About ASCENIV™
ASCENIV (immune globulin intravenous, human – slra 10% liquid) is a plasma-derived, polyclonal, intravenous immune globulin (IVIG). ASCENIV was approved by the
Additional Important Safety Information About ASCENIV™
| WARNING: THROMBOSIS, RENAL DYSFUNCTION AND ACUTE RENAL FAILURE |
| Thrombosis may occur with immune globulin intravenous (IGIV) products, including ASCENIV. Risk factors may include: advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling vascular catheters, hyperviscosity, and cardiovascular risk factors. Renal dysfunction, acute renal failure, osmotic nephrosis, and death may occur with the administration of IGIV products in predisposed patients. Renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products containing sucrose. ASCENIV does not contain sucrose. For patients at risk of thrombosis, renal dysfunction or renal failure, administer ASCENIV at the minimum dose and infusion rate practicable. Ensure adequate hydration in patients before administration. Monitor for signs and symptoms of thrombosis and assess blood viscosity in patients at risk for hyperviscosity. |
ASCENIV™ Contraindications:
History of anaphylactic or severe systemic reactions to human immunoglobulin.
IgA deficient patients with antibodies to IgA and a history of hypersensitivity.
ASCENIV™ Warnings and Precautions:
IgA-deficient patients with antibodies against IgA are at greater risk of developing severe hypersensitivity and anaphylactic reactions. Have medications such as epinephrine available to treat any acute severe hypersensitivity reactions. [4, 5.1]
Thrombotic events have occurred in patients receiving IGIV treatments. Monitor patients with known risk factors for thrombotic events; consider baseline assessment of blood viscosity for patients at risk of hyperviscosity. [5.2, 5.4]
In patients at risk of developing acute renal failure. monitor renal function, including blood urea nitrogen (BUN), serum creatinine, and urine output. [5.3, 5.9]
Hyperproteinemia, increased serum viscosity, and hyponatremia or pseudohyponatremia can occur in patients receiving IGIV treatment.
Aseptic meningitis syndrome (AMS) has been reported with IGIV treatments, especially with high doses or rapid infusion. [5.5]
Hemolytic anemia can develop subsequent to IGIV treatment. Monitor patients for hemolysis and hemolytic anemia. [5.6]
Monitor patients for pulmonary adverse reactions (Transfusion-related acute lung injury [TRALI]). If transfusion related acute lung injury is suspected, test the product and patient for antineutrophil antibodies. [5.7]
Because this product is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses, and theoretically, the Creutzfeldt-Jakob disease (CJD) agent.
ASCENIV™ Adverse Reactions:
The most common adverse reactions to ASCENIV (=5% of study subjects) were headache, sinusitis, diarrhea, gastroenteritis viral, nasopharyngitis, upper respiratory tract infection, bronchitis, and nausea
To report SUSPECTED ADVERSE REACTIONS, contact
About
Use of Non-GAAP Financial Measures
This press release includes certain non-GAAP financial measures that are not prepared in accordance with accounting principles generally accepted in
Cautionary Note Regarding Forward-Looking Statements
This press release contains “forward-looking statements” pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, about
(1) Adjusted Net Income is a non-GAAP financial measure. The estimated Adjusted Net Income amounts included herein are preliminary and reconciliations cannot be produced at this time without unreasonable effort. The Company expects to provide a reconciliation of Adjusted Net Income to the most comparable GAAP measure in its earnings release relating to the fourth quarter and full year 2025 audited financial results.
(2) Adjusted EBITDA is a non-GAAP financial measure. The estimated Adjusted EBITDA amounts included herein are preliminary and reconciliations cannot be produced at this time without unreasonable effort. The Company expects to provide a reconciliation of Adjusted EBITDA to the most comparable GAAP measure in its earnings release relating to the fourth quarter and full year 2025 audited financial results.
INVESTOR RELATIONS CONTACT:
| 2025 | 2024 | |||||||
| (In thousands, except share data) | ||||||||
| ASSETS | ||||||||
| Current assets: | ||||||||
| Cash and cash equivalents | $ | 87,630 | $ | 103,147 | ||||
| Accounts receivable, net | 158,429 | 49,999 | ||||||
| Inventories | 206,465 | 170,235 | ||||||
| Prepaid expenses and other current assets | 7,458 | 8,029 | ||||||
| Assets held for sale | 6,530 | - | ||||||
| Total current assets | 466,512 | 331,410 | ||||||
| Property and equipment, net | 65,057 | 54,707 | ||||||
| Intangible assets, net | 632 | 460 | ||||||
| 3,530 | 3,530 | |||||||
| Deferred tax assets, net | 73,261 | 84,280 | ||||||
| Right-of-use assets | 6,650 | 8,634 | ||||||
| Deposits and other assets | 8,600 | 5,657 | ||||||
| TOTAL ASSETS | $ | 624,242 | $ | 488,678 | ||||
| LIABILITIES AND STOCKHOLDERS' EQUITY | ||||||||
| Current liabilities: | ||||||||
| Accounts payable | $ | 22,519 | $ | 20,219 | ||||
| Accrued expenses and other current liabilities | 40,466 | 34,105 | ||||||
| Current portion of long term debt | 2,813 | - | ||||||
| Current portion of lease obligations | 1,096 | 1,218 | ||||||
| Liabilities held for sale | 2,647 | - | ||||||
| Total current liabilities | $ | 69,541 | $ | 55,542 | ||||
| Long-term debt | 69,330 | 72,337 | ||||||
| Deferred revenue, net of current portion | 1,405 | 1,547 | ||||||
| End of term fee | - | 1,313 | ||||||
| Lease obligations, net of current portion | 6,646 | 8,561 | ||||||
| Other non-current liabilities | - | 360 | ||||||
| TOTAL LIABILITIES | 146,922 | 139,660 | ||||||
| COMMITMENTS AND CONTINGENCIES | ||||||||
| STOCKHOLDERS' EQUITY | ||||||||
| Preferred Stock, | - | - | ||||||
| no shares issued and outstanding | ||||||||
| Common Stock - voting, | ||||||||
| December, 31, 2025 239,793,566 issued and 237,874,496 shares outstanding: | 24 | 24 | ||||||
| (32,090 | ) | - | ||||||
| Additional paid-in capital | 671,039 | 657,577 | ||||||
| Accumulated deficit | (161,653 | ) | (308,583 | ) | ||||
| TOTAL STOCKHOLDERS' EQUITY | 477,320 | 349,018 | ||||||
| TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY | 624,242 | 488,678 | ||||||
| Three Months ended | Year ended | ||||||||||||||||
| 2025 | 2024 | 2025 | 2024 | ||||||||||||||
| (In thousands, except share and per share data) | |||||||||||||||||
| Unaudited | |||||||||||||||||
| REVENUES | $ | 139,163 | $ | 117,549 | $ | 510,173 | $ | 426,454 | |||||||||
| Cost of product revenue | 50,347 | 54,216 | 217,408 | 206,901 | |||||||||||||
| Gross profit | 88,816 | 63,333 | 292,765 | 219,553 | |||||||||||||
| OPERATING EXPENSES: | |||||||||||||||||
| Research and development | 1,376 | 391 | 4,762 | 1,813 | |||||||||||||
| Plasma center operating expenses | 1,126 | 1,277 | 4,836 | 4,245 | |||||||||||||
| Amortization of intangible assets | 51 | 25 | 144 | 388 | |||||||||||||
| Selling, general and administrative | 23,512 | 23,317 | 91,580 | 74,124 | |||||||||||||
| Total operating expenses | 26,065 | 25,010 | 101,322 | 80,570 | |||||||||||||
| INCOME FROM OPERATIONS | 62,751 | 38,323 | 191,443 | 138,983 | |||||||||||||
| OTHER INCOME (EXPENSE): | |||||||||||||||||
| Interest income | 487 | 598 | 1,871 | 2,097 | |||||||||||||
| Interest expense | (1,626 | ) | (2,879 | ) | (7,110 | ) | (13,930 | ) | |||||||||
| Loss on extinguishment of debt | - | (1,243 | ) | (3,336 | ) | (1,243 | ) | ||||||||||
| Other expense | (17 | ) | (86 | ) | (212 | ) | (193 | ) | |||||||||
| Other expense, net | (1,155 | ) | (3,610 | ) | (8,787 | ) | (13,269 | ) | |||||||||
| INCOME BEFORE INCOME TAXES | 61,595 | 34,713 | 182,656 | 125,714 | |||||||||||||
| Income tax expense (benefit) | 12,216 | (77,183 | ) | 35,726 | (71,959 | ) | |||||||||||
| NET INCOME | $ | 49,379 | $ | 111,896 | $ | 146,930 | $ | 197,673 | |||||||||
| BASIC EARNINGS PER COMMON SHARE | $ | 0.21 | $ | 0.47 | $ | 0.62 | $ | 0.85 | |||||||||
| DILUTED EARNINGS PER COMMON SHARE | $ | 0.20 | $ | 0.46 | $ | 0.60 | $ | 0.81 | |||||||||
| WEIGHTED AVERAGE COMMON SHARES OUTSTANDING: | |||||||||||||||||
| Basic | 237,971,602 | 236,433,759 | 238,299,024 | 233,084,236 | |||||||||||||
| Diluted | 243,854,484 | 245,900,655 | 244,904,640 | 243,342,466 | |||||||||||||
| NON-GAAP RECONCILIATION RECONCILIATION OF GAAP NET INCOME TO ADJUSTED EBITDA (2) | |||||||||||||||
| Three Months ended | Year ended | ||||||||||||||
| 2025 | 2024 | 2025 | 2024 | ||||||||||||
| (In thousands) | |||||||||||||||
| Net income | $ | 49,379 | $ | 111,896 | $ | 146,930 | $ | 197,673 | |||||||
| Depreciation | 1,995 | 1,919 | 7,952 | 7,657 | |||||||||||
| Amortization | 51 | 25 | 144 | 388 | |||||||||||
| Income tax expense (benefit) | 12,216 | (77,183 | ) | 35,726 | (71,959 | ) | |||||||||
| Interest expense | 1,626 | 2,879 | 7,110 | 13,930 | |||||||||||
| EBITDA | 65,267 | 39,536 | 197,862 | 147,689 | |||||||||||
| Stock-based compensation | 5,392 | 5,433 | 20,026 | 13,616 | |||||||||||
| Voluntary Withdrawal and product replacements | 2,214 | - | 6,215 | - | |||||||||||
| Yield enhancement expense | 114 | 2,064 | 1,810 | 2,064 | |||||||||||
| Loss on extinguishment of debt | - | 1,243 | 3,336 | 1,243 | |||||||||||
| Non-recurring professional fees(a) | 599 | - | 1,781 | - | |||||||||||
| Adjusted EBITDA | $ | 73,586 | $ | 48,276 | $ | 231,030 | $ | 164,612 | |||||||
| NON-GAAP RECONCILIATION RECONCILIATION OF GAAP NET INCOME TO ADJUSTED NET INCOME (1) | |||||||||||||||
| Three Months ended | Year ended | ||||||||||||||
| 2025 | 2024 | 2025 | 2024 | ||||||||||||
| (In thousands) | |||||||||||||||
| Net income | $ | 49,379 | $ | 111,896 | $ | 146,930 | $ | 197,673 | |||||||
| Deferred income tax benefit | - | (84,280 | ) | - | (84,280 | ) | |||||||||
| Loss on extinguishment of debt (pre-tax) | - | 1,243 | 3,336 | 1,243 | |||||||||||
| Stock-based compensation modifications (pre-tax) | 283 | 2,518 | 757 | 2,518 | |||||||||||
| Yield Enhancement expense (pre-tax) | 114 | 2,064 | 1,810 | 2,064 | |||||||||||
| Voluntary Withdrawal and product replacements (pre-tax) | 2,214 | - | 6,215 | - | |||||||||||
| Non-recurring professional fees (pre-tax)(a) | 599 | - | 1,781 | - | |||||||||||
| Adjusted Net Income(b) | $ | 52,589 | $ | 33,441 | $ | 160,829 | $ | 119,218 | |||||||
| (a) Non-recurring professional fees represent incremental costs associated with a vendor change that we do not expect to incur in future periods and other one-time professional fees. | |||||||||||||||
| (b) Excludes estimated tax effect of the add-backs of | |||||||||||||||
| PRODUCT-LEVEL TOTAL REVENUE | ||||||||||||
| Year Ended | ||||||||||||
| 2025 | 2024 | Increase/ (Decrease) | Increase/ (Decrease) % | |||||||||
| (in thousands) | ||||||||||||
| ASCENIV | $ | 362,531 | $ | 239,594 | $ | 122,937 | 51 | |||||
| BIVIGAM | 122,033 | 142,357 | (20,324 | ) | (14 | ) | ||||||
| Intermediates and other products (1) | 8,579 | 33,998 | (25,419 | ) | (75 | ) | ||||||
| ADMA BioManufacturing | 493,143 | 415,949 | 77,194 | 19 | ||||||||
| Plasma Collection Centers | 17,030 | 10,505 | 6,525 | 62 | ||||||||
| Total Revenues | $ | 510,173 | $ | 426,454 | $ | 83,719 | 20 | |||||
Source: 