- Five additional pivotal trials for pumitamig initiated during 2026 in collaboration with Bristol Myers Squibb
- Oncology pipeline strength and combination strategy highlighted through multiple clinical data updates, including pumitamig, gotistobart and antibody-drug conjugate programs
- Catalyst-rich year ahead with six late-stage pipeline data readouts expected across immunomodulators, antibody-drug conjugate and mRNA cancer immunotherapies
- COVID-19 2026/2027 season variant-adapted vaccine development and commercial preparation underway
- Operational efficiency to be enhanced through manufacturing footprint consolidation, supporting strategic capital allocation to further advance its growing oncology pipeline toward commercialization
- First quarter 2026 revenues of €118.1 million1, net loss of €531.9 million (adjusted2 net loss of €494.6 million), with diluted loss per share of €2.10 (
$2.46 3) (adjusted2 diluted loss per share of €1.95 ($2.28 3)) - Reaffirmed full year 2026 financial guidance and strong financial position continue to de-risk execution with cash, cash equivalents and security investments of €16.8 billion4
- Share repurchase program of up to
$1.0 billion over twelve months planned
Conference call and webcast scheduled for
MAINZ, Germany, May 5, 2026 (GLOBE NEWSWIRE) --
“In the first quarter, we made substantial progress in executing towards our oncology strategy, highlighted by data presentations from our priority pan-tumor program pumitamig as well as our versatile antibody-drug conjugate portfolio. Simultaneously, we continue to broaden our clinical programs to include novel-novel combinations in order to inform the optimal set-up for registrational combination trials and maximize the potential of our pipeline,” said Prof.
Financial Review for First Quarter 2026
| in millions €, except per share data | First Quarter 2026 | First Quarter 2025 | |||||||||
| IFRS Results | Adjusted Results2 | IFRS Results | Adjusted Results2 | ||||||||
| Revenues | 118.1 | 118.1 | 182.8 | 182.8 | |||||||
| Net loss | (531.9) | (494.6) | (415.8) | (430.8) | |||||||
| Diluted loss per share | (2.10) | (1.95) | (1.73) | (1.79) | |||||||
Revenues for the first quarter of 2026 were €118.1 million, compared to €182.8 million for the comparative prior year period. The decrease was primarily driven by lower revenues of BioNTech’s COVID-19 vaccines.
Research and development (“R&D”) expenses were €557.0 million for the first quarter of 2026, compared to €525.6 million for the comparative prior year period. R&D expenses were mainly driven by higher expenses for the development of immuno-oncology (“IO”) and antibody-drug conjugate (“ADC”) programs, in particular pumitamig and gotistobart, as well as costs from operations of entities acquired during 2025, BioNTech China (previously Biotheus) and CureVac, and an impairment of an intangible asset. These effects were partly offset by lower R&D expenses related to the Company’s COVID-19 vaccine collaboration with Pfizer Inc. (“Pfizer”).
Adjusted R&D expenses were €527.1 million for the first quarter of 2026, compared to €525.6 million for the comparative prior year period. For the first quarter of 2026, adjusted R&D expenses exclude the impairment of an intangible asset.
Sales, general and administrative (“SG&A”) expenses5 were €150.8 million for the first quarter of 2026, compared to €120.6 million for the comparative prior year period. The increase was mainly driven by the ongoing commercial build-up and the inclusion of operations of entities acquired in 2025, BioNTech China (previously Biotheus) and CureVac. These costs were partly offset by a reduction in external services.
Net loss was €531.9 million for the first quarter of 2026, compared to a net loss of €415.8 million for the comparative prior year period.
Adjusted net loss was €494.6 million for the first quarter of 2026, compared to an adjusted net loss of €430.8 million for the comparative prior year period.
Diluted loss per share was €2.10 for the first quarter of 2026, compared to a diluted loss per share of €1.73 for the comparative prior year period.
Adjusted diluted loss per share was €1.95 for the first quarter of 2026, compared to adjusted diluted loss per share of €1.79 for the comparative prior year period.
Cash, cash equivalents and security investments as of
Shares outstanding as of
“Our revenues for the first quarter reflect the seasonal demand for COVID-19 vaccines and are in line with our expectations,” said
Reaffirmed 2026 Financial Year Guidance6:
| Revenues for the 2026 financial year | €2,000 – €2,300 m |
In 2026,
Planned 2026 Financial Year Adjusted Expenses6:
| Adjusted R&D expenses | €2,200 – €2,500 m | |
| Adjusted SG&A expenses5 | €700 – €800 m |
Planned Capital Return to Shareholders
The Management Board and Supervisory Board expect to authorize a share repurchase program of BioNTech’s American Depositary Shares (“ADSs”), pursuant to which the Company may repurchase ADSs in the amount of up to
Manufacturing Footprint Consolidation
The full interim unaudited condensed consolidated financial statements can be found in BioNTech’s Report on Form 6-K for the period ended March 31, 2026, filed today with the
Endnotes
1 All numbers in this press release have been rounded.
2 In addition to BioNTech’s results determined in accordance with International Financial Reporting Standards (“IFRS”), or IFRS Accounting Standards, or IFRS results,
3 Calculated applying the average foreign exchange rate for the three months ended
4 As of
5 Sales, general and administrative expenses (“SG&A”) include sales and marketing expenses as well as general and administrative expenses. Adjusted SG&A expenses include adjusted sales and marketing expenses as well as adjusted general and administrative expenses.
6 Excludes risks that are not yet known and/or quantifiable and related activities. Includes effects identified from licensing arrangements, collaborations and Merger & Acquisitions (“M&A”) transactions to the extent disclosed. The guidance is based on non-IFRS measures and excludes certain effects compared to measures based on IFRS Accounting Standards. More information can be found in BioNTech’s Report on Form 6-K for the period ended
7 Expected savings relative to
8 An overview of abbreviations of target structures and indications is compiled in a directory at the end of this press release.
Select Oncology Pipeline Updates
Next-Generation Immunomodulators and Combinations
Pumitamig (BNT327/BMS986545) is an investigational bispecific immunomodulator combining PD-L18 checkpoint inhibition with VEGF-A neutralization that is being developed in collaboration with BMS.
- In the first quarter of 2026, the following pivotal trials evaluating pumitamig were initiated:
- A global Phase 3 clinical trial in patients with first-line triple-negative breast cancer (“TNBC”) (ROSETTA Breast-01; NCT07173751).
- A global Phase 2/3 clinical trial in first-line microsatellite stable colorectal cancer (“MSS-CRC”) (ROSETTA
CRC-203 ; NCT07221357). - A global Phase 2/3 clinical trial in first-line gastric cancer (ROSETTA Gastric-204; NCT07221149).
- A global Phase 3 clinical trial (ROSETTA Lung-201; NCT07361497) is being conducted to evaluate pumitamig compared to durvalumab following concurrent chemoradiation therapy in patients with unresectable stage III non-small cell lung cancer (“NSCLC”).
- A global Phase 3 clinical trial (ROSETTA Lung-202; NCT07361510) is being conducted to evaluate pumitamig compared to pembrolizumab as a first-line treatment for patients with advanced PD-L1 = 50% NSCLC.
- A global Phase 2/3 clinical trial (ROSETTA Lung-02; NCT06712316) is ongoing to evaluate pumitamig in combination with chemotherapy compared to pembrolizumab and chemotherapy in patients with first-line NSCLC. The Phase 3 part of the trial is currently recruiting. Data from the Phase 2 part of the trial are expected at the
American Society of Clinical Oncology (“ASCO”) Annual Meeting 2026 (May 29 - June 2 , 2026). - Pumitamig is also being evaluated in additional solid tumor indications, including first-line hepatocellular carcinoma (“HCC”), second-line glioblastoma (“GBM”), first-line pancreatic ductal adenocarcinoma (“PDAC”) and first-line renal cell carcinoma (“RCC”) in various Phase 1/2 and Phase 2 trials, both as monotherapy and in combination with standard of care.
BioNTech has several signal-seeking clinical trials ongoing evaluating pumitamig with the Company’s proprietary assets. These trials will inform the dose selection for pumitamig and explore anti-tumor activity in multiple tumors for later-stage development. Multiple data readouts from these combinations are expected in 2026.- In
April 2026 ,BioNTech andBoehringer Ingelheim announced a clinical trial collaboration to assess the safety, tolerability and early clinical activity of pumitamig in combination with obrixtamig (BI 764532), Boehringer Ingelheim’s investigational DLL3/CD3 T-cell engager, in extensive-stage small cell lung cancer (“ES-SCLC”). Under the agreement,BioNTech will supply pumitamig andBoehringer Ingelheim will be the regulatory sponsor of the Phase 1b/2 trial.
Gotistobart (BNT316/ONC-392) is a tumor microenvironment-selective regulatory T cell depletion candidate that targets CTLA-4 and is being developed in collaboration with
- A global Phase 3 clinical trial (PRESERVE-003; NCT05671510) is ongoing to evaluate the efficacy and safety of gotistobart as monotherapy in patients with metastatic squamous NSCLC that progressed under previous platinum-based chemotherapy and PD-(L)1-inhibitor treatment.
- In
March 2026 , updated data from the non-pivotal dose-confirmation stage, the first of two stages of the global Phase 3 clinical trial, were presented at theEuropean Lung Cancer Congress (“ELCC”). Gotistobart demonstrated a clinically meaningful overall survival benefit compared to standard of care chemotherapy and a manageable safety profile in patients with squamous NSCLC whose disease had progressed following anti-PD-(L)1 therapy and platinum-based chemotherapy. - Based on current event accrual projections, interim data from the pivotal stage of the two-stage Phase 3 clinical trial are expected in 2026.
- In
January 2026 , gotistobart received Orphan Drug Designation from theU.S. Food and Drug Administration (“FDA”) for the treatment of squamous NSCLC. In 2022, gotistobart received Fast Track Designation from the FDA for the treatment of patients with metastatic NSCLC whose disease progressed on prior anti-PD-(L)1 therapy.
Antibody-Drug Conjugates
Trastuzumab pamirtecan (BNT323/DB-1303) is an ADC candidate targeting HER2 that is being developed in collaboration with
- A Phase 1/2 clinical trial (NCT05150691) is being conducted to evaluate trastuzumab pamirtecan in patients with advanced HER2-expressing tumors. A potentially registrational cohort with HER2-expressing (IHC3+, 2+, 1+ or ISH-positive) patients with recurrent endometrial cancer (“EC”) is fully recruited.
- In
April 2026 , updated data from this trial were presented at theSociety of Gynecologic Oncology (“SGO”) Annual Meeting. Trastuzumab pamirtecan demonstrated encouraging clinical efficacy across all HER2 expression levels and regardless of prior immunotherapy treatment. The safety profile in patients with pretreated advanced or metastatic EC was manageable and generally consistent with that of HER2-targeted biologics. BioNTech and DualityBio plan to file a biologics license application (“BLA”) in 2026, subject to regulatory feedback.- A Phase 3 trial (FERN-EC-01, NCT06340568) is being conducted to evaluate trastuzumab pamirtecan compared to investigator’s choice of chemotherapy in patients with advanced and HER2-expessing recurrent EC.
- A global Phase 3 clinical trial (DYNASTY-Breast02, NCT06018337) to evaluate trastuzumab pamirtecan in patients with HR-positive, HER2-low metastatic breast cancer is ongoing. Based on current event accrual projections, data are expected in 2026.
BNT324/DB-1311 is an ADC candidate targeting B7H3 that is being developed in collaboration with DualityBio.
- In
February 2026 , updated data from a Phase 1/2 clinical trial (NCT05914116) were presented at the ASCO Genitourinary Cancers Symposium. BNT324/DB-1311 demonstrated durable efficacy in heavily pretreated metastatic castration-resistant prostate cancer (“mCRPC”) patients with no new safety signals reported. - In
April 2026 , updated data from this trial were presented at the SGO Annual Meeting. BNT324/DB-1311 showed encouraging efficacy in previously treated cervical cancer and platinum resistant ovarian cancer (“PROC”) particularly in patients with treatment-naïve cervical cancer. The safety profile in gynecologic malignancies was consistent with previous reports, and no new safety signals were observed. - A Phase 3 clinical trial (NCT07365995) to evaluate BNT324/DB-1311 compared to docetaxel in patients with mCRPC, is expected to initiate in 2026.
Corporate and Commercial Update for the First Quarter 2026 and Post Period Events
BioNTech and Pfizer developed, manufactured and delivered their variant-adapted COVID-19 vaccines, which have received multiple regulatory approvals, including full approvals, authorizations for emergency or temporary use or marketing authorizations, in more than 40 countries and regions.BioNTech is now focused on preparing for variant strain vaccine adaptation to be ready for commercial launch ahead of the upcoming 2026/2027 vaccination season, pending approvals.- In
March 2026 ,BioNTech announced plans for an independent company to be established and led byBioNTech co-founders Prof.Ugur Sahin , M.D., and Prof. Özlem Türeci, M.D. The new company with distinct resources, operations and funding options will advance next-generation mRNA innovations.BioNTech plans to contribute related rights and mRNA technologies to the new company to enable and support the prioritized development of next-generation mRNA innovations with disruptive potential. With both companies focusing on their respective strategic priorities,BioNTech expects to maximize value for patients and shareholders alike.Ugur Sahin and Özlem Türeci will transition into the management of their new company by the end of 2026 after their current service agreements end. BioNTech’s Supervisory Board has initiated an executive search to identify successors for the positions to ensure a smooth transition and seamless execution of BioNTech’s strategy. - In
March 2026 ,BioNTech published its Sustainability Report 2025.BioNTech recognizes the responsibility it has in how it is conducting its business and the impact its activities have on the economy, people, and the environment. The Sustainability Report 2025 outlinesBioNTech's efforts, progress, key initiatives, and data as well as highlights in its corporate sustainability and responsibility over the past year.
Upcoming Investor and Analyst Events
- BioNTech Annual General Meeting: May 15, 2026
- BioNTech Second Quarter 2026 Financial Results and Corporate Update: August 4, 2026
Conference Call and Webcast Information
To access the live conference call via telephone, please register via this link. Once registered, dial-in numbers and a PIN number will be provided.
The slide presentation and audio of the webcast will be available via this link.
Participants may also access the slides and the webcast of the conference call via the “Events & Presentations” page of the Investor section of the Company’s website at www.BioNTech.com. A replay of the webcast will be made available shortly after the closing of the call and archived on the Company’s website for 30 days following the call.
About
For more information, please visit www.BioNTech.com.
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, but not limited to, statements concerning: expected changes to BioNTech’s leadership and the transition of responsibilities at the Management Board, including identification and recruitment of successors; the terms of the preliminary discussions between
The forward-looking statements in this press release are based on BioNTech’s current expectations and beliefs of future events, and are neither promises nor guarantees. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond BioNTech’s control and which could cause actual results to differ materially and adversely from those expressed or implied by these forward-looking statements. These risks and uncertainties include, but are not limited to: the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and/or completion dates for clinical trials, projected data release timelines, regulatory submission dates, regulatory approval dates and/or launch dates, as well as risks associated with preclinical and clinical data, including the data discussed in this release, and including the possibility of unfavorable new preclinical, clinical or safety data and further analyses of existing preclinical, clinical or safety data; the nature of the clinical data, which is subject to ongoing peer review, regulatory review and market interpretation; BioNTech’s pricing and coverage negotiations with governmental authorities, private health insurers and other third-party payors; the future commercial demand and medical need for initial or annual booster doses of a COVID-19 vaccine; the impact of tariffs and escalations in trade policy; competition from other COVID-19 vaccines or related to BioNTech’s other product candidates; the timing of and BioNTech’s ability to obtain and maintain regulatory approval for its product candidates; the ability of BioNTech’s COVID-19 vaccines to prevent COVID-19 caused by emerging virus variants; BioNTech’s ability to identify research opportunities and discover and develop investigational medicines; the ability and willingness of BioNTech’s third-party collaborators to continue research and development activities relating to
You should review the risks and uncertainties described under the heading “Risk Factors” in BioNTech’s Report on Form 6-K for the period ended
CONTACTS
Investor Relations
Investors@biontech.de
Media Relations
Jasmina Alatovic
Media@biontech.de
Abbreviation Overview
| 1L | First line |
| 2L | Second line |
| ADC | Antibody-drug conjugate |
| B7H3 | Also known as CD276, cluster of differentiation 276 |
| BLA | Biologics license application |
| CTLA-4 | Cytotoxic T-lymphocyte-associated protein |
| EC | Endometrial cancer |
| ES-SCLC | Extensive-stage small cell lung cancer |
| GBM | Glioblastoma |
| HCC | Hepatocellular carcinoma |
| HER2 (or HER3) | Human epidermal growth factor receptor 2 (or 3) |
| HPV16 | Human papilloma virus 16 |
| HR | Hormone receptor |
| IHC3+, 2+, 1+ | Immunohistochemistry score 1+ (or 2+ or 3+) |
| IO | Immuno-oncology |
| ISH-positive | In-situ hybridization positive |
| mCRPC | Metastatic castration-resistant prostate cancer |
| MSS-CRC | Microsatellite stable colorectal cancer |
| NSCLC | Non-small cell lung cancer |
| PDAC | Pancreatic ductal adenocarcinoma |
| PD-(L)1 | Programmed cell death protein (death-ligand) 1 |
| PROC | Platinum resistant ovarian cancer |
| RCC | Renal cell carcinoma |
| SCLC | Small cell lung cancer |
| TNBC | Triple-negative breast cancer |
| TROP2 | Trophoblast cell-surface antigen 2 |
| VEGF-A | Vascular endothelial growth factor A |
Interim Condensed Consolidated Statements of Profit or Loss
| Three months ended | ||||||
| 2026 | 2025 | |||||
| (in millions €, except per share data) | (unaudited) | (unaudited) | ||||
| Revenues | 118.1 | 182.8 | ||||
| Cost of sales | (71.4) | (83.8) | ||||
| Research and development expenses | (557.0) | (525.6) | ||||
| Sales and marketing expenses | (27.9) | (13.7) | ||||
| General and administrative expenses | (122.9) | (106.9) | ||||
| Other operating expenses | (46.8) | (48.5) | ||||
| Other operating income | 30.4 | 61.6 | ||||
| Operating loss | (677.5) | (534.1) | ||||
| Finance income | 120.6 | 122.6 | ||||
| Finance expenses | (11.2) | (33.9) | ||||
| Loss before tax | (568.1) | (445.4) | ||||
| Income taxes | 36.2 | 29.6 | ||||
| Net loss | (531.9) | (415.8) | ||||
| Loss per share | ||||||
| Basic and diluted loss per share | (2.10) | (1.73) | ||||
Interim Condensed Consolidated Statements of Profit or Loss
(Adjusted Results)
| Adjusted Results (non-IFRS measures)1 | Three months ended | |||||
| 2026 | 2025 | |||||
| (in millions €, except per share data) | (unaudited) | (unaudited) | ||||
| Adjusted research and development expenses | (527.1) | (525.6) | ||||
| Adjusted other operating expenses | (39.4) | (48.5) | ||||
| Adjusted other operating income | 30.4 | 46.6 | ||||
| Adjusted operating loss | (640.2) | (549.1) | ||||
| Adjusted loss before tax | (530.8) | (460.4) | ||||
| Adjusted net loss2 | (494.6) | (430.8) | ||||
| Adjusted loss per share | ||||||
| Adjusted basic and diluted loss per share | (1.95) | (1.79) | ||||
1 Certain adjusted results presented in this table are identical to BioNTech’s results under IFRS Accounting Standards. Reconciliation of all other adjusted results to the Company’s IFRS results can be found at the end of this press release and in BioNTech’s Report on Form 6-K for the period ended
2 Tax effects are not considered as part of our non-IFRS adjustments.
Interim Condensed Consolidated Statements of Financial Position
| (in millions €) | 2026 | 2025 | ||||
| Assets | (unaudited) | |||||
| Non-current assets | ||||||
| 370.5 | 367.9 | |||||
| Other intangible assets | 1,546.8 | 1,606.0 | ||||
| Property, plant and equipment | 1,112.7 | 1,080.9 | ||||
| Right-of-use assets | 205.5 | 210.2 | ||||
| Contract assets | — | 2.0 | ||||
| Other financial assets | 2,279.9 | 2,554.2 | ||||
| Other non-financial assets | 12.2 | 7.3 | ||||
| Deferred tax assets | 14.7 | 13.5 | ||||
| Total non-current assets | 5,542.3 | 5,842.0 | ||||
| Current assets | ||||||
| Inventories | 103.8 | 110.7 | ||||
| Trade and other receivables | 539.2 | 924.2 | ||||
| Contract assets | 8.9 | 8.1 | ||||
| Other financial assets | 4,699.8 | 7,201.8 | ||||
| Other non-financial assets | 176.6 | 173.8 | ||||
| Income tax assets | 64.1 | 52.6 | ||||
| Cash and cash equivalents | 9,939.4 | 7,675.4 | ||||
| Total current assets | 15,531.8 | 16,146.6 | ||||
| Total assets | 21,074.1 | 21,988.6 | ||||
| Equity and liabilities | ||||||
| Equity | ||||||
| Share capital | 259.0 | 259.0 | ||||
| Capital reserve | 2,468.2 | 2,473.3 | ||||
| (6.1) | (7.7) | |||||
| Retained earnings | 17,430.0 | 17,961.9 | ||||
| Other reserves | (1,453.3) | (1,462.3) | ||||
| Total equity | 18,697.8 | 19,224.2 | ||||
| Non-current liabilities | ||||||
| Lease liabilities, loans and borrowings | 246.1 | 215.2 | ||||
| Other financial liabilities | 92.0 | 94.9 | ||||
| Provisions | 23.8 | 35.5 | ||||
| Contract liabilities | 87.7 | 88.0 | ||||
| Other non-financial liabilities | 108.8 | 104.2 | ||||
| Deferred tax liabilities | 52.9 | 84.3 | ||||
| Total non-current liabilities | 611.3 | 622.1 | ||||
| Current liabilities | ||||||
| Lease liabilities, loans and borrowings | 56.7 | 52.2 | ||||
| Trade payables and other payables | 468.8 | 534.9 | ||||
| Other financial liabilities | 77.5 | 351.7 | ||||
| Income tax liabilities | 38.1 | 65.6 | ||||
| Provisions | 167.0 | 145.3 | ||||
| Contract liabilities | 758.5 | 754.9 | ||||
| Other non-financial liabilities | 198.4 | 237.7 | ||||
| Total current liabilities | 1,765.0 | 2,142.3 | ||||
| Total liabilities | 2,376.3 | 2,764.4 | ||||
| Total equity and liabilities | 21,074.1 | 21,988.6 |
Interim Condensed Consolidated Statements of Cash Flows
| Three months ended | ||||||
| 2026 | 2025 | |||||
| (in millions €) | (unaudited) | (unaudited) | ||||
| Operating activities | ||||||
| Net loss | (531.9) | (415.8) | ||||
| Income taxes | (36.2) | (29.6) | ||||
| Loss before tax | (568.1) | (445.4) | ||||
| Adjustments to reconcile loss before tax to net cash flows: | ||||||
| Depreciation, amortization and impairment of property, plant, equipment, intangible assets and right-of-use assets | 121.3 | 42.8 | ||||
| Share-based payment expenses | 22.8 | 22.1 | ||||
| Net foreign exchange differences | 0.4 | 48.3 | ||||
| Gain on disposal of property, plant and equipment | (0.1) | (0.1) | ||||
| Finance income excluding foreign exchange differences | (111.0) | (122.6) | ||||
| Finance expense excluding foreign exchange differences | 11.2 | 7.9 | ||||
| Government and similar grants | (17.6) | (14.5) | ||||
| Other non-cash income | — | (15.0) | ||||
| Working capital adjustments: | ||||||
| Decrease in trade and other receivables, contract assets and other assets | 431.1 | 520.7 | ||||
| Decrease in inventories | 7.0 | 33.8 | ||||
| Decrease in trade payables, other financial liabilities, other liabilities, contract liabilities, refund liabilities and provisions | (371.9) | (981.6) | ||||
| Interest received and realized gains from cash and cash equivalents | 86.6 | 118.6 | ||||
| Interest paid and realized losses from cash and cash equivalents | (3.3) | (3.1) | ||||
| Income tax paid, net | (41.6) | (12.2) | ||||
| Share-based payments | (2.1) | (3.6) | ||||
| Government and similar grants received | 14.3 | 23.2 | ||||
| Net cash flows used in operating activities | (421.0) | (780.7) | ||||
| Investing activities | ||||||
| Purchase of property, plant and equipment | (56.8) | (48.9) | ||||
| Proceeds from sale of property, plant and equipment | 1.6 | 0.5 | ||||
| Purchase of intangible assets | (22.1) | (569.2) | ||||
| Acquisition of subsidiaries and businesses, net of cash acquired | — | (78.5) | ||||
| Investment in other financial assets | (1,550.2) | (2,507.7) | ||||
| Proceeds from maturity of other financial assets | 4,278.1 | 4,450.6 | ||||
| Net cash flows from investing activities | 2,650.6 | 1,246.8 | ||||
| Financing activities | ||||||
| Proceeds from loans and borrowings | 38.4 | — | ||||
| Repayment of loans and borrowings | (0.1) | (4.5) | ||||
| Payments related to lease liabilities | (11.9) | (9.3) | ||||
| Net cash flows from / (used in) financing activities | 26.4 | (13.8) | ||||
| Net increase in cash and cash equivalents | 2,256.0 | 452.3 | ||||
| Change in cash and cash equivalents resulting from exchange rate differences | (3.4) | (16.1) | ||||
| Change in cash and cash equivalents resulting from other valuation effects | 11.4 | (13.2) | ||||
| Cash and cash equivalents at the beginning of the period | 7,675.4 | 9,761.9 | ||||
| Cash and cash equivalents as of | 9,939.4 | 10,184.9 | ||||
Certain prior period lines were aggregated to conform to current period presentation.
Non-IFRS Reconciliation
| Non-IFRS Reconciliation for the three months ended | ||||||||||||||
| non-IFRS adjustments (unaudited) | ||||||||||||||
| (in millions €, except per share data) | IFRS Results | Expenses and income from legal proceedings | Impairment and reversal | Employee-related expenses from restructuring | Income from bargain purchase and income and expenses from divestiture related items | Adjusted Results | ||||||||
| (unaudited) | (unaudited) | |||||||||||||
| Research and development expenses | (557.0) | — | 29.9 | — | — | (527.1) | ||||||||
| Other operating expenses | (46.8) | — | — | 7.4 | — | (39.4) | ||||||||
| Operating loss | (677.5) | — | 29.9 | 7.4 | — | (640.2) | ||||||||
| Loss before tax | (568.1) | — | 29.9 | 7.4 | — | (530.8) | ||||||||
| Net loss1 | (531.9) | — | 29.9 | 7.4 | — | (494.6) | ||||||||
| Loss per share | ||||||||||||||
| Basic and diluted loss per share | (2.10) | (1.95) | ||||||||||||
1 Tax effects are not considered as part of
| Non-IFRS Reconciliation for the three months ended | |||||||||||||
| non-IFRS adjustments (unaudited) | |||||||||||||
| (in millions €, except per share data) | IFRS Results | Expenses and income from legal proceedings | Impairment and reversal | Employee-related expenses from restructuring | Income from bargain purchase and income and expenses from divestiture related items | Adjusted Results | |||||||
| (unaudited) | (unaudited) | ||||||||||||
| Other operating income | 61.6 | — | — | — | (15.0) | 46.6 | |||||||
| Operating loss | (534.1) | — | — | — | (15.0) | (549.1) | |||||||
| Loss before tax | (445.4) | — | — | — | (15.0) | (460.4) | |||||||
| Net loss1 | (415.8) | — | — | — | (15.0) | (430.8) | |||||||
| Loss per share | |||||||||||||
| Basic and diluted loss per share | (1.73) | (1.79) | |||||||||||
1 Tax effects are not considered as part of
Source: