Highlights
- First quarter 2026 revenue of
$200.4 million grew 2% year-over-year, reflecting stable test volume and 2% year-over-year growth in average revenue per test. - First quarter 2026 test volume reflects 13% and 7% test volume growth year-over-year in
Cancer Care Continuum and Mental Health, respectively, offset by a 12% decline year-over-year inPrenatal Health test volume. - Launched Precise Molecular Residual Disease (MRD),
Myriad Genetics' ultrasensitive assay, representing progress toward earlier insight, more informed decisions, and better outcomes for cancer patients. - Received FDA approval of the MyChoice CDx test as the companion diagnostic for Zejula®, for patients with advanced ovarian cancer.
- First quarter 2026 gross margin was 68.7%, up 20.0 basis points from the first quarter 2025.
- First quarter 2026 GAAP net loss of
$34.1 million , or$0.36 per share, while adjusted loss per share was$0.09 per share and adjusted EBITDA was$(4.5) million .
"We are seeing strong performance across a number of key areas, including the Cancer Care Continuum as we begin to realize a return on our focused strategy. We have implemented a dedicated hereditary cancer sales force and other key programs designed to support the expected continued growth in germline testing. And with decisive steps taken to address our
Financial and Operational Highlights
- Test volumes of 385,000 in the first quarter of 2026 were stable year-over-year.
- The following table summarizes year-over-year testing volume changes in the company's core product categories:
| Three Months Ended | |||||||
| (in thousands) | 2026 | 2025 | % Change | ||||
| Product volumes: | |||||||
| Cancer Care Continuum | 96 | 85 | 13 | % | |||
| 153 | 173 | (12 | )% | ||||
| Mental Health | 136 | 127 | 7 | % | |||
| Total | 385 | 385 | — | % | |||
- The following table summarizes year-over-year revenue changes in the company's core product categories:
| Three Months Ended | |||||||||
| (in millions) | 2026 | 2025 | % Change | ||||||
| Product revenues: | |||||||||
| Cancer Care Continuum | $ | 120.2 | $ | 115.6 | 4 | % | |||
| 41.9 | 49.3 | (15 | )% | ||||||
| Mental Health | 38.3 | 31.0 | 24 | % | |||||
| Total | $ | 200.4 | $ | 195.9 | 2 | % | |||
Product Categories:
Cancer Care Continuum – MyRisk, BRACAnalysis CDx, MyChoice CDx, Prolaris, Precise Tumor, Precise MRD
Mental Health – GeneSight
- Operating expenses in the first quarter of 2026 were
$168.3 million , increasing$5.1 million year-over-year. Adjusted operating expenses in the first quarter of 2026 increased$7.9 million year-over-year to$148.5 million , partially reflecting the company's progress in its multi-year investment program in key strategic areas. - Operating loss in the first quarter of 2026 was
$30.7 million .
Cash Flow and Liquidity
First quarter 2026 cash flow used in operations was
As of the end of the first quarter of 2026, the company had cash and cash equivalents of
Business Performance and Highlights
Cancer Care Continuum
The Cancer Care Continuum business delivered revenue of
- First quarter 2026 hereditary cancer testing revenue increased 5% year-over-year driven by a 14% year-over-year increase in volume.
- First quarter 2026 Prolaris testing revenue grew 3% year-over-year. The company continues to make progress on its first AI-enabled prostate cancer test, in partnership with PATHOMIQ, and expects to launch the test in the second quarter of 2026.
- In
April 2026 , the company shared new data at a number of annual clinical society meetings, including theAmerican Association for Cancer Research (AACR) and theSociety of Gynecologic Oncology (SGO) underscoringMyriad Genetics' commitment to the Cancer Care Continuum and highlighting its progress in precision oncology. For example, data from one poster presentation showed that Precise MRD testing after adjuvant therapy for ovarian cancer is significantly prognostic of recurrence and that elevated risk was observed even at ctDNA levels detectable only by an ultrasensitive assay. The company believes this data reinforces the scientific strength behind the company's precision oncology programs and focus on advancing clinically meaningful innovations for patients and providers. - In
April 2026 ,Myriad Genetics received approval from Japan’sMinistry of Health, Labour and Welfare (MHLW) for the use of the MyChoice CDx test for prostate cancer patients as a companion diagnostic for Lynparza®(olaparib). With this approval, clinicians inJapan can now order the MyChoice CDx test to determine homologous recombination deficiency (HRD) status for patients with ovarian cancer, and BRCA1/2 status for breast and prostate cancers.
- Prenatal testing revenue in the first quarter of 2026 declined 15% year-over-year, as volume decreased 12% year-over-year reflecting a difficult year-over-year comparison as the company continues to engage with customers and address the disruption caused by the Q2 '25 implementation of the company's new order management system.
- In
April 2026 , a national payor updated its medical policy to cover expanded carrier screen tests, like the Company's Foresight Universal Plus test. - The multi-site CONNECTOR study, using the company's FirstGene Multiple Prenatal Screen, continues to see progress in enrollment and the Company expects this study, if successful, to support future commercial launch activities and expand capabilities in prenatal testing.
Mental Health
GeneSight test revenue was
- First quarter 2026 revenue grew 24% year-over-year reflecting 7% GeneSight volume growth, and overall improved reimbursement trends.
Financial Guidance
Below is a table summarizing
| (in millions, except percentages) | 2026 Guidance | FY 2026 Comments | ||
| Revenue | Reiterate the full year 2026 revenue range, reflecting current business trends. Expect 2H’26 revenue to be greater than 1H’26 | |||
| Adjusted Gross Margin %** | 68% - 69% | Gross margins expected to fluctuate quarter to quarter given product mix and pricing trends. | ||
| Adjusted EBITDA*** | ||||
| * | Assumes currency rates as of | |||
| ** | Adjusted Gross Margin is defined as Gross Margin plus non-cash cost of sales, such as amortization of intangible assets and share-based compensation expense, and non-recurring one-time expenses. | |||
| *** | Adjusted EBITDA is defined as Net income (loss) plus income tax expense (benefit), total other income (expense), non-cash operating expenses, such as amortization of intangible assets, depreciation, impairment of goodwill and long-lived assets, and share-based compensation expense, and one-time expenses such as expenses from strategic realignment.. | |||
These projections are forward-looking statements and are subject to the risks summarized in the safe harbor statement at the end of this press release.
Conference Call and Webcast
A conference call will be held today,
About
Myriad, the Myriad logo, BRACAnalysis, BRACAnalysis CDx, Colaris, MyRisk, Myriad myRisk, MyRisk Hereditary Cancer, MyChoice, Tumor BRACAnalysis CDx, MyChoice CDx, Prequel, Prequel with Amplify, Amplify, Foresight, Foresight Universal Plus, Precise Tumor, Precise Oncology Solutions, Precise Liquid, Precise MRD, FirstGene, SneakPeek, SneakPeek Early Gender DNA Test, SneakPeek Snap, Urosuite, myGeneHistory, Health.Illuminated., RiskScore, Prolaris, and GeneSight are registered trademarks or trademarks of
© 2026
AND SUBSIDIARIES Condensed Consolidated Statements of Operations (unaudited) (in millions, except per share amounts) | |||||||
| Three months ended | |||||||
| 2026 | 2025 | ||||||
| Revenue | $ | 200.4 | $ | 195.9 | |||
| Cost of revenue | 62.8 | 61.7 | |||||
| Gross profit | 137.6 | 134.2 | |||||
| Operating expenses: | |||||||
| Research and development expense | 27.1 | 27.5 | |||||
| Sales and marketing expense | 73.6 | 69.2 | |||||
| General and administrative expense | 62.2 | 66.5 | |||||
| 5.4 | — | ||||||
| Total operating expenses | 168.3 | 163.2 | |||||
| Operating loss | (30.7 | ) | (29.0 | ) | |||
| Other income (expense): | |||||||
| Interest income | 0.7 | 0.3 | |||||
| Interest expense | (4.1 | ) | (0.8 | ) | |||
| Other | — | 0.1 | |||||
| Total other expense | (3.4 | ) | (0.4 | ) | |||
| Loss before income tax | (34.1 | ) | (29.4 | ) | |||
| Income tax benefit | — | 29.3 | |||||
| Net loss | $ | (34.1 | ) | $ | (0.1 | ) | |
| Net loss per share: | |||||||
| Basic and diluted | $ | (0.36 | ) | $ | — | ||
| Weighted average shares outstanding: | |||||||
| Basic and diluted | 93.7 | 91.4 | |||||
AND SUBSIDIARIES Condensed Consolidated Balance Sheets (unaudited) (in millions, except per share amounts) | |||||||
| ASSETS | |||||||
| Current assets: | |||||||
| Cash and cash equivalents | $ | 124.4 | $ | 149.6 | |||
| Trade accounts receivable | 123.8 | 115.3 | |||||
| Inventory | 27.9 | 30.6 | |||||
| Prepaid taxes | 2.0 | 12.0 | |||||
| Prepaid expenses and other current assets | 34.7 | 25.1 | |||||
| Total current assets | 312.8 | 332.6 | |||||
| Operating lease right-of-use assets | 51.0 | 49.4 | |||||
| Property, plant and equipment, net | 111.5 | 114.0 | |||||
| Intangible assets, net | 145.7 | 153.4 | |||||
| 47.1 | 51.6 | ||||||
| Other assets | 5.6 | 5.6 | |||||
| Total assets | $ | 673.7 | $ | 706.6 | |||
| LIABILITIES AND STOCKHOLDERS' EQUITY | |||||||
| Current liabilities: | |||||||
| Accounts payable | $ | 32.6 | $ | 30.0 | |||
| Accrued liabilities | 90.5 | 96.9 | |||||
| Current maturities of operating lease liabilities | 7.1 | 6.9 | |||||
| Total current liabilities | 130.2 | 133.8 | |||||
| Long-term debt | 120.3 | 119.9 | |||||
| Noncurrent operating lease liabilities | 84.1 | 83.0 | |||||
| Other long-term liabilities | 1.7 | 1.9 | |||||
| Total liabilities | 336.3 | 338.6 | |||||
| Commitments and contingencies | |||||||
| Stockholders’ equity: | |||||||
| Common stock, 94.4 and 93.5 shares outstanding at | 0.9 | 0.9 | |||||
| Additional paid-in capital | 1,492.6 | 1,489.0 | |||||
| Accumulated other comprehensive income | 0.7 | 0.8 | |||||
| Accumulated deficit | (1,156.8 | ) | (1,122.7 | ) | |||
| Total stockholders' equity | 337.4 | 368.0 | |||||
| Total liabilities and stockholders’ equity | $ | 673.7 | $ | 706.6 | |||
AND SUBSIDIARIES Condensed Consolidated Statements of Cash Flows (unaudited) (in millions) | |||||||
| Three months ended | |||||||
| 2026 | 2025 | ||||||
| Net cash used in operating activities | $ | (15.7 | ) | $ | (16.3 | ) | |
| Net cash used in investing activities | (6.5 | ) | (8.3 | ) | |||
| Net cash provided by (used in) financing activities | (3.0 | ) | 13.6 | ||||
| Effect of foreign exchange rates on cash, cash equivalents, and restricted cash | (0.1 | ) | 0.1 | ||||
| Net decrease in cash, cash equivalents, and restricted cash | (25.3 | ) | (10.9 | ) | |||
| Cash, cash equivalents, and restricted cash at beginning of the period | 151.3 | 111.9 | |||||
| Cash, cash equivalents, and restricted cash at end of the period | $ | 126.0 | $ | 101.0 | |||
Safe Harbor Statement
This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including statements related to (i) the company's full-year 2026 financial guidance, (ii) the company's programs designed to support the expected continued growth in germline testing as the company moves forward, (iii) the company's expectation of improved performance in the remainder of 2026, (iv) the company's expectation that it remains on track with its other planned launches in 2026, including its first AI-enabled prostate cancer test, in partnership with PATHOMIQ, which the company expects to launch in the second quarter of 2026, and (v) the company's confidence that these tests will be important drivers of the company's growth in 2027 and beyond. These “forward-looking statements” are management’s present expectations of future events as of the date hereof and are subject to a number of known and unknown risks and uncertainties that could cause actual results, conditions, and events to differ materially and adversely from those anticipated.
These risks include, but are not limited to: the risk that sales and profit margins of the company’s existing tests may decline; the risk that the company may not be able to operate its business on a profitable basis; risks related to the company’s ability to achieve certain revenue growth targets and generate sufficient revenue from its existing product portfolio or in launching and commercializing new tests to be profitable; risks related to recent changes in the company's senior management team and the successful implementation of the company's strategic plan; risks related to changes in governmental or private insurers’ coverage and reimbursement levels for the company’s tests or the company’s ability to obtain reimbursement for its new tests at comparable levels to its existing tests; risks related to increased competition and the development of new competing tests; the risk that the company may be unable to develop or achieve commercial success for additional tests in a timely manner, or at all; the risk that the company is not able to secure additional financing to fund its business, if needed, in a timely manner or on favorable terms, if at all; the risk that the company may not successfully develop new markets or channels for its tests; the risk that licenses to the technology underlying the company’s tests and any future tests are terminated or cannot be maintained on satisfactory terms; risks related to delays or other problems with operating the company’s laboratory testing facilities; risks related to public concern over genetic testing in general or the company’s tests in particular; risks related to regulatory requirements or enforcement in
Investor Contact
(801) 584-3532
matt.scalo@myriad.com
Media Contact
(224) 875-4493
PR@myriad.com
Statement Regarding use of Non-GAAP Financial Measures
In this press release, the company’s financial results and financial guidance are provided in accordance with accounting principles generally accepted in
The company encourages investors to carefully consider its results under GAAP, as well as its supplemental non-GAAP information and the reconciliation between these presentations, if available, to more fully understand its business. Non-GAAP financial results are reported in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP.
The company does not forecast GAAP gross margin or GAAP net income (loss) because it cannot predict certain elements that are included in reported GAAP results. Please see above under “Financial Guidance” for a full explanation.
Reconciliation of GAAP to Non-GAAP Financial Measures
for the Three Months Ended
(unaudited data in millions, except per share amounts)
| Three months ended | ||||||||
| 2026 | 2025 | |||||||
| Adjusted Gross Margin | ||||||||
| Gross Profit | $ | 137.6 | $ | 134.2 | ||||
| Acquisition - amortization of intangible assets(1) | 0.1 | 0.3 | ||||||
| Equity compensation(2) | 0.2 | 0.3 | ||||||
| Other adjustments(3) | — | 0.3 | ||||||
| Adjusted Gross Profit | $ | 137.9 | $ | 135.1 | ||||
| Adjusted Gross Margin | 68.8 | % | 69.0 | % | ||||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||
| (2) | Consists of the non-cash equity-based compensation provided to | |||||||
| (3) | Other one-time non-recurring expenses. | |||||||
| Three months ended | ||||||||
| 2026 | 2025 | |||||||
| Adjusted Operating Expenses | ||||||||
| Operating Expenses | $ | 168.3 | $ | 163.2 | ||||
| Acquisition - amortization of intangible assets(1) | (6.4 | ) | (8.8 | ) | ||||
| (5.4 | ) | — | ||||||
| Equity compensation(3) | (6.3 | ) | (9.2 | ) | ||||
| Real estate optimization(4) | — | (3.0 | ) | |||||
| Strategic realignment(5) | (1.7 | ) | (1.7 | ) | ||||
| Other adjustments(6) | — | 0.1 | ||||||
| Adjusted Operating Expenses | $ | 148.5 | $ | 140.6 | ||||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||
| (2) | Expense related to goodwill and long-lived asset impairment. For the three months ended | |||||||
| (3) | Consists of the non-cash equity-based compensation provided to | |||||||
| (4) | Costs related to real estate initiatives. For the three months ended | |||||||
| (5) | Costs related to strategic realignment of the company including severance and consulting fees. During the three months ended | |||||||
| (6) | Other one-time non-recurring adjustments. See also Note 5 above regarding reclassification of other adjustments to strategic realignment. | |||||||
| Three months ended | ||||||||
| 2026 | 2025 | |||||||
| Adjusted Net Loss(1) | ||||||||
| Net Loss | $ | (34.1 | ) | $ | (0.1 | ) | ||
| Acquisition - amortization of intangible assets(2) | 6.5 | 9.1 | ||||||
| 5.4 | — | |||||||
| Equity compensation(4) | 6.5 | 9.5 | ||||||
| Real estate optimization(5) | — | 3.0 | ||||||
| Strategic realignment(6) | 1.7 | 1.7 | ||||||
| Other adjustments(7) | — | 0.2 | ||||||
| Uncertain tax benefit(8) | — | (28.7 | ) | |||||
| Tax adjustments(9) | 5.8 | 2.2 | ||||||
| Adjusted Net Loss | $ | (8.2 | ) | $ | (3.1 | ) | ||
| Weighted average shares outstanding: | ||||||||
| Diluted | 93.7 | 91.4 | ||||||
| Adjusted Loss Per Share | ||||||||
| Diluted | $ | (0.09 | ) | $ | (0.03 | ) | ||
| (1) | To determine Adjusted Loss Per Share. | |||||||
| (2) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||
| (3) | Expense related to goodwill and long-lived asset impairment. For the three months ended | |||||||
| (4) | Consists of the non-cash equity-based compensation provided to | |||||||
| (5) | Costs related to real estate initiatives. For the three months ended | |||||||
| (6) | Costs related to strategic realignment of the company including severance and consulting fees. During the three months ended | |||||||
| (7) | Other one-time non-recurring adjustments. See also Note 6 above regarding reclassification of other adjustments to strategic realignment. | |||||||
| (8) | Consists of the release of unrecognized tax benefits and the recognition of valuation allowances for the three months ended | |||||||
| (9) | Tax expense or benefit due to non-GAAP adjustments, differences between stock compensation recorded for book purposes as compared to the allowable tax deductions, and valuation allowance recognized against federal and state deferred tax assets in | |||||||
| Three months ended | ||||||||
| 2026 | 2025 | |||||||
| Adjusted EBITDA | ||||||||
| Net Loss | $ | (34.1 | ) | $ | (0.1 | ) | ||
| Acquisition - amortization of intangible assets(1) | 6.5 | 9.1 | ||||||
| Depreciation expense(2) | 4.7 | 5.1 | ||||||
| 5.4 | — | |||||||
| Equity compensation(4) | 6.5 | 9.5 | ||||||
| Real estate optimization(5) | — | 3.0 | ||||||
| Strategic realignment(6) | 1.7 | 1.7 | ||||||
| Interest expense, net of interest income(7) | 3.4 | 0.5 | ||||||
| Other adjustments(8) | 1.4 | 0.4 | ||||||
| Uncertain tax benefits(9) | — | (28.7 | ) | |||||
| Income tax (benefit) expense(10) | — | (0.6 | ) | |||||
| Adjusted EBITDA | $ | (4.5 | ) | $ | (0.1 | ) | ||
| (1) | Represents recurring amortization charges resulting from the acquisition of intangible assets. | |||||||
| (2) | Consists of depreciation expense recognized during the period. | |||||||
| (3) | Expense related to goodwill and long-lived asset impairment. For the three months ended | |||||||
| (4) | Consists of the non-cash equity-based compensation provided to | |||||||
| (5) | Costs related to real estate initiatives. For the three months ended | |||||||
| (6) | Costs related to strategic realignment of the company including severance and consulting fees. During the three months ended | |||||||
| (7) | Derived from interest expense and interest income from the Condensed Consolidated Statements of Operations. | |||||||
| (8) | Other one-time non-recurring expenses. For purposes of adjusted EBITDA, this includes Other adjustments described in the Adjusted Net Loss table above as well as the amounts reported as Other income (expense) in the Condensed Consolidated Statement of Operations. See also Note 6 above regarding the reclassification of other adjustments to strategic realignment. | |||||||
| (9) | Consists of the release of unrecognized tax benefits and the recognition of valuation allowances for the three months ended | |||||||
| (10) | Derived from income tax (benefit) expense from the Condensed Consolidated Statement of Operations, net of the adjustment for unrecognized tax benefits described in Note 9 above. | |||||||
| Three months ended | ||||||||
| 2026 | 2025 | |||||||
| Adjusted Operating and Free Cash Flow | ||||||||
| $ | (15.7 | ) | $ | (16.3 | ) | |||
| Real estate optimization(1) | — | 4.0 | ||||||
| Strategic realignment(2) | 2.3 | 1.7 | ||||||
| Other adjustments(3) | — | 0.2 | ||||||
| Adjusted Operating Cash Flow | $ | (13.4 | ) | $ | (10.4 | ) | ||
| Capital expenditures(4) | (5.4 | ) | (5.3 | ) | ||||
| Capitalization of internal-use software costs(4) | (1.1 | ) | (3.0 | ) | ||||
| Adjusted Free Cash Flow | $ | (19.9 | ) | $ | (18.7 | ) | ||
| (1) | The cash flow effect of real estate optimizations, excluding non-cash items such as accelerated depreciation. | |||||||
| (2) | Strategic realignment includes the cash paid for those costs in the related periods. During the three months ended | |||||||
| (3) | The cash flow effect of other one-time non-recurring expenses. See also Note 2 above regarding the reclassification of other adjustments to strategic realignment. | |||||||
| (4) | Derived from the Condensed Consolidated Statements of Cash Flows. | |||||||
Source: 