BCYC Bicycle Therapeutics plc

NASDAQ
$4.37

Bicycle Therapeutics plc (BCYC) Institutional Ownership

What the institutions did with BCYC last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
117
filed a 13F this quarter
Managers holding
104
+6 on the quarter
Buyers
53
19 opened new
Sellers
31
13 sold out entirely
Buyer share
63.1%
of managers who traded it
Breadth
+26.2
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
BAKER BROS. ADVISORS LP 10.9M 29.1%
FCPM III SERVICES B.V. 3.5M 9.3%
ARMISTICE CAPITAL, LLC 3.4M 9.1%
Long Focus Capital Management, LLC 3.3M 8.8%
ACADIAN ASSET MANAGEMENT LLC 2.0M 5.3%
RENAISSANCE TECHNOLOGIES LLC 1.5M 4.1%
GSK plc 1.5M 4.1%
PRICE T ROWE ASSOCIATES INC /MD/ 902.2K 2.4%
MARSHALL WACE, LLP 797.9K 2.1%
Qube Research & Technologies Ltd 775.6K 2.1%
MORGAN STANLEY 667.3K 1.8%
SCHRODER INVESTMENT MANAGEMENT GROUP 615.8K 1.6%
CITADEL ADVISORS LLC 554.2K 1.5%
MILLENNIUM MANAGEMENT LLC 554.0K 1.5%
Peapod Lane Capital LLC 538.0K 1.4%
DIADEMA PARTNERS LP 462.7K 1.2%
TWO SIGMA INVESTMENTS, LP 434.6K 1.2%
JANE STREET GROUP, LLC 392.2K 1.0%
FLAX POND CAPITAL, LLC 376.2K 1.0%
Birchview Capital, LP 313.6K 0.8%
BlackRock, Inc. 280.4K 0.7%
MOORE CAPITAL MANAGEMENT, LP 275.0K 0.7%
Rangeley Capital, LLC 253.5K 0.7%
Palo Alto Investors LP 201.9K 0.5%
Sculptor Capital LP 197.9K 0.5%

Largest changes

Manager Action Previous Current Change
Siren, L.L.C. Sold Out 1.6M 0 -1.6M
PRINCIPAL FINANCIAL GROUP INC Sold Out 1.2M 0 -1.2M
RENAISSANCE TECHNOLOGIES LLC Increased 979.3K 1.5M +554.1K
Qube Research & Technologies Ltd Increased 308.6K 775.6K +467.0K
SILVERCREST ASSET MANAGEMENT GROUP LLC Sold Out 428.7K 0 -428.7K
MARSHALL WACE, LLP Increased 377.3K 797.9K +420.6K
Peapod Lane Capital LLC Increased 121.1K 538.0K +416.9K
MILLENNIUM MANAGEMENT LLC Increased 284.0K 554.0K +270.0K
TWO SIGMA INVESTMENTS, LP Increased 164.8K 434.6K +269.8K
FLAX POND CAPITAL, LLC Increased 176.1K 376.2K +200.1K
Sculptor Capital LP New 0 197.9K +197.9K
PLATINUM INVESTMENT MANAGEMENT LTD Sold Out 184.6K 0 -184.6K
CITADEL ADVISORS LLC Increased 377.1K 554.2K +177.1K
JANE STREET GROUP, LLC Increased 218.1K 392.2K +174.0K
Birchview Capital, LP Reduced 463.6K 313.6K -150.0K
PRICE T ROWE ASSOCIATES INC /MD/ Reduced 1.0M 902.2K -126.1K
Marex Group plc Sold Out 115.0K 0 -115.0K
Jump Financial, LLC Increased 52.5K 167.1K +114.6K
Quadrature Capital Ltd New 0 104.1K +104.1K
NANO CAP NEW MILLENNIUM GROWTH FUND L P New 0 80.0K +80.0K
Marquette Asset Management, LLC New 0 72.9K +72.9K
Man Group plc Sold Out 63.3K 0 -63.3K
Verdad Advisers, LP New 0 51.1K +51.1K
MORGAN STANLEY Increased 618.3K 667.3K +48.9K
Virtus Investment Advisers, LLC Increased 36.6K 80.8K +44.2K

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.