EWTX Edgewise Therapeutics, Inc.

NASDAQ
$44.18

Edgewise Therapeutics, Inc. (EWTX) Institutional Ownership

What the institutions did with EWTX last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
245
filed a 13F this quarter
Managers holding
219
+11 on the quarter
Buyers
120
37 opened new
Sellers
98
26 sold out entirely
Buyer share
55.1%
of managers who traded it
Breadth
+10.1
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
ORBIMED ADVISORS LLC 15.5M 13.0%
Paradigm Biocapital Advisors LP 10.2M 8.6%
RA CAPITAL MANAGEMENT, L.P. 8.4M 7.0%
BlackRock, Inc. 6.6M 5.5%
Jupiter Topco LLC 6.1M 5.1%
FMR LLC 5.5M 4.6%
NOVO HOLDINGS A/S 5.4M 4.5%
Driehaus Capital Management LLC 4.7M 4.0%
PERCEPTIVE ADVISORS LLC 4.4M 3.7%
VANGUARD CAPITAL MANAGEMENT LLC 3.9M 3.2%
BAKER BROS. ADVISORS LP 3.7M 3.1%
Siren, L.L.C. 3.2M 2.7%
Cormorant Asset Management, LP 2.5M 2.1%
GEODE CAPITAL MANAGEMENT, LLC 2.2M 1.8%
ALLIANCEBERNSTEIN L.P. 2.1M 1.8%
Integral Health Asset Management, LLC 2.0M 1.7%
BRAIDWELL LP 2.0M 1.7%
MORGAN STANLEY 1.9M 1.6%
STATE STREET CORP 1.8M 1.5%
MPM BIOIMPACT LLC 1.6M 1.4%
BANK OF AMERICA CORP /DE/ 1.6M 1.3%
Qube Research & Technologies Ltd 1.3M 1.1%
DIMENSIONAL FUND ADVISORS LP 1.1M 1.0%
AMERICAN CENTURY COMPANIES INC 1.1M 0.9%
First Light Asset Management, LLC 1.1M 0.9%

Largest changes

Manager Action Previous Current Change
FMR LLC Increased 1.0M 5.5M +4.5M
BAKER BROS. ADVISORS LP Reduced 6.6M 3.7M -2.9M
Paradigm Biocapital Advisors LP Increased 7.4M 10.2M +2.9M
RA CAPITAL MANAGEMENT, L.P. Reduced 10.4M 8.4M -2.0M
Bellevue Group AG Sold Out 1.5M 0 -1.5M
Siren, L.L.C. Reduced 4.4M 3.2M -1.2M
UBS Group AG Reduced 1.3M 175.0K -1.1M
Soleus Capital Management, L.P. Reduced 1.4M 450.9K -999.0K
Cormorant Asset Management, LP Reduced 3.3M 2.5M -750.0K
PRICE T ROWE ASSOCIATES INC /MD/ Increased 69.4K 816.5K +747.1K
MARSHALL WACE, LLP Reduced 648.4K 6.1K -642.3K
Tyro Capital Management LLC New 0 613.0K +613.0K
STEMPOINT CAPITAL LP Sold Out 581.7K 0 -581.7K
ADAGE CAPITAL PARTNERS GP, L.L.C. New 0 462.0K +462.0K
Candriam S.C.A. Sold Out 447.4K 0 -447.4K
Qube Research & Technologies Ltd Increased 825.9K 1.3M +426.6K
Integral Health Asset Management, LLC Increased 1.6M 2.0M +400.0K
ALLIANCEBERNSTEIN L.P. Increased 1.7M 2.1M +396.9K
GEODE CAPITAL MANAGEMENT, LLC Increased 1.8M 2.2M +384.2K
BRAIDWELL LP Reduced 2.3M 2.0M -350.6K
MILLENNIUM MANAGEMENT LLC Sold Out 342.9K 0 -342.9K
RAYMOND JAMES FINANCIAL INC Increased 19.7K 317.6K +297.9K
MORGAN STANLEY Reduced 2.2M 1.9M -297.4K
DIADEMA PARTNERS LP New 0 272.2K +272.2K
Sio Capital Management, LLC Sold Out 269.0K 0 -269.0K

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.