GPCR Structure Therapeutics Inc.

NASDAQ
$49.09

Structure Therapeutics Inc. (GPCR) Institutional Ownership

What the institutions did with GPCR last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
222
filed a 13F this quarter
Managers holding
191
-3 on the quarter
Buyers
104
28 opened new
Sellers
82
31 sold out entirely
Buyer share
55.9%
of managers who traded it
Breadth
+11.8
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
FMR LLC 7.8M 11.6%
WELLINGTON MANAGEMENT GROUP LLP 7.4M 10.9%
Avoro Capital Advisors LLC 6.6M 9.7%
Jupiter Topco LLC 5.2M 7.7%
Deep Track Capital, LP 4.7M 7.0%
BVF INC/IL 3.4M 5.0%
MORGAN STANLEY 2.8M 4.2%
ORBIMED ADVISORS LLC 2.2M 3.3%
PRINCIPAL FINANCIAL GROUP INC 1.8M 2.6%
AMERICAN CENTURY COMPANIES INC 1.7M 2.5%
RTW INVESTMENTS, LP 1.6M 2.4%
Driehaus Capital Management LLC 1.6M 2.3%
BAKER BROS. ADVISORS LP 1.4M 2.1%
Casdin Capital, LLC 1.2M 1.7%
DEERFIELD MANAGEMENT COMPANY, L.P. 1.1M 1.6%
CAPITOLIS LIQUID GLOBAL MARKETS LLC 1.0M 1.5%
Siren, L.L.C. 873.0K 1.3%
PRICE T ROWE ASSOCIATES INC /MD/ 845.5K 1.3%
Pacific Heights Asset Management LLC 800.0K 1.2%
Rock Springs Capital Management LP 640.3K 0.9%
Aberdeen Group plc 639.9K 0.9%
ALLIANCEBERNSTEIN L.P. 611.7K 0.9%
FRANKLIN RESOURCES INC 578.8K 0.9%
BANK OF AMERICA CORP /DE/ 563.4K 0.8%
BlackRock, Inc. 511.1K 0.8%

Largest changes

Manager Action Previous Current Change
RTW INVESTMENTS, LP New 0 1.6M +1.6M
PRICE T ROWE ASSOCIATES INC /MD/ Reduced 2.0M 845.5K -1.2M
ORBIMED ADVISORS LLC Increased 1.5M 2.2M +734.0K
FMR LLC Reduced 8.4M 7.8M -593.1K
Paradigm Biocapital Advisors LP Sold Out 545.3K 0 -545.3K
MORGAN STANLEY Increased 2.3M 2.8M +501.2K
Deep Track Capital, LP Increased 4.3M 4.7M +460.2K
Siren, L.L.C. Reduced 1.3M 873.0K -455.7K
STEMPOINT CAPITAL LP Reduced 400.5K 38.2K -362.4K
BANK OF AMERICA CORP /DE/ Increased 227.1K 563.4K +336.3K
Davern Capital Partners, LP Increased 126.5K 446.1K +319.6K
DEERFIELD MANAGEMENT COMPANY, L.P. Increased 768.0K 1.1M +318.0K
Balyasny Asset Management L.P. Sold Out 304.9K 0 -304.9K
Parkman Healthcare Partners LLC Increased 232.1K 485.7K +253.6K
Aberdeen Group plc Increased 391.8K 639.9K +248.1K
Pentwater Capital Management LP Sold Out 245.0K 0 -245.0K
AMERICAN CENTURY COMPANIES INC Increased 1.4M 1.7M +244.1K
Sio Capital Management, LLC Sold Out 209.1K 0 -209.1K
JPMORGAN CHASE & CO Reduced 212.8K 4.0K -208.8K
MARSHALL WACE, LLP Increased 69.1K 267.6K +198.5K
NEXTBio Capital Management LP Increased 133.2K 312.5K +179.3K
UBS Group AG Increased 212.9K 379.0K +166.1K
Holocene Advisors, LP Sold Out 159.0K 0 -159.0K
VOLORIDGE INVESTMENT MANAGEMENT, LLC Reduced 255.0K 112.3K -142.7K
TCG Crossover Management, LLC Sold Out 140.4K 0 -140.4K

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.