KRYS Krystal Biotech, Inc.

NASDAQ
$340.03

Krystal Biotech, Inc. (KRYS) Hedge Fund Activity

This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.

Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.

Hedge fund breadth
-36.36
7 buyers / 15 sellers
STRONG SELLING
Funds compared
24
funds with comparable KRYS positions
15 current holders · 23 prior-quarter holders
Net share change
-282.1K
+92.1K added, -374.2K cut
Position activity
1 new 6 increased 6 reduced 9 exited

Most significant moves

Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.

Fund Action Shares changed Change Est. value Portfolio wt. Score
Soleus Capital Management Growth Healthcare Reduced -213.8K -18.5% $79.5M 12.0% 61
MARSHALL WACE, LLP Long/Short Sold Out -68.3K -100.0% $25.4M 0.0% 60
Farallon Capital Management Event Value Sold Out -1.0K -100.0% $371.7K 0.0% 60
MILLENNIUM MANAGEMENT LLC Sold Out -4.1K -100.0% $1.5M 0.0% 59
TWO SIGMA INVESTMENTS, LP Quant New +6.1K — $2.3M 0.0% 59
D. E. Shaw & Co., Inc. Quant Sold Out -996 -100.0% $370.2K 0.0% 58
RENAISSANCE TECHNOLOGIES LLC Quant Increased +50.1K +521.7% $18.6M 0.0% 56
Tudor Investment Corporation Macro Sold Out -14.5K -100.0% $5.4M 0.0% 56
Quadrature Capital Quant Sold Out -3.2K -100.0% $1.2M 0.0% 55
Squarepoint Ops LLC Quant Sold Out -1.1K -100.0% $423.0K 0.0% 54

Most significant buyers

By move score, not size.

  • TWO SIGMA INVESTMENTS, LP New · +6.1K
  • RENAISSANCE TECHNOLOGIES LLC Increased · +50.1K
  • Cinctive Capital Management Increased · +13.5K
  • Quantbot Technologies Increased · +172
  • Bridgewater Associates Increased · +8.1K

Most significant sellers

By move score, not size.

  • Soleus Capital Management Reduced · -213.8K
  • MARSHALL WACE, LLP Sold Out · -68.3K
  • Farallon Capital Management Sold Out · -1.0K
  • MILLENNIUM MANAGEMENT LLC Sold Out · -4.1K
  • D. E. Shaw & Co., Inc. Sold Out · -996

Hedge fund positions

Fund Tier Shares Previous Change Change % Portfolio wt. Action Score
Soleus Capital Management 2 939.3K 1.2M -213.8K -18.5% 12.0% Reduced 61
MARSHALL WACE, LLP 2 0 68.3K -68.3K -100.0% 0.0% Sold Out 60
Farallon Capital Management 1 0 1.0K -1.0K -100.0% 0.0% Sold Out 60
MILLENNIUM MANAGEMENT LLC 2 0 4.1K -4.1K -100.0% 0.0% Sold Out 59
TWO SIGMA INVESTMENTS, LP 2 6.1K 0 +6.1K — 0.0% New 59
D. E. Shaw & Co., Inc. 1 0 996 -996 -100.0% 0.0% Sold Out 58
RENAISSANCE TECHNOLOGIES LLC 1 59.7K 9.6K +50.1K +521.7% 0.0% Increased 56
Tudor Investment Corporation 2 0 14.5K -14.5K -100.0% 0.0% Sold Out 56
Quadrature Capital 3 0 3.2K -3.2K -100.0% 0.0% Sold Out 55
Squarepoint Ops LLC 2 0 1.1K -1.1K -100.0% 0.0% Sold Out 54
Hudson Bay Capital Management 3 0 1.3K -1.3K -100.0% 0.0% Sold Out 53
Aquatic Capital Management 4 0 8.3K -8.3K -100.0% 0.0% Sold Out 50
Cinctive Capital Management 3 16.4K 2.9K +13.5K +469.5% 0.3% Increased 47
Braidwell 2 129.0K 182.4K -53.5K -29.3% 1.9% Reduced 46
Walleye Capital 3 12 354 -342 -96.6% 0.0% Reduced 44
Quantbot Technologies 4 305 133 +172 +129.3% 0.0% Increased 39
Bridgewater Associates 1 54.5K 46.4K +8.1K +17.5% 0.1% Increased 37
OrbiMed Advisors 2 83.2K 69.1K +14.1K +20.4% 0.6% Increased 36
ADAR1 Capital Management 3 16.4K 20.0K -3.6K -18.0% 0.3% Reduced 30
CITADEL ADVISORS LLC 1 2.7K 2.7K -1 -+0.0% 0.0% Reduced 27
Gotham Asset Management, LLC 2 1.3K 1.3K +7 +0.5% 0.0% Increased 24
AQR Capital Management 3 14.0K 14.1K -112 -0.8% 0.0% Reduced 20
Avoro Capital Advisors 1 2.9M 2.9M 0 +0.0% 9.6% Unchanged 50
Woodline Partners LP 2 150.6K 150.6K 0 +0.0% 0.2% Unchanged 19

Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.

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Hedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.