LXRX Lexicon Pharmaceuticals, Inc.
Lexicon Pharmaceuticals, Inc. (LXRX) Hedge Fund Activity
This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.
Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.
Most significant moves
Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.
| Fund | Action | Shares changed | Change | Est. value | Portfolio wt. | Score |
|---|---|---|---|---|---|---|
| MARSHALL WACE, LLP Long/Short | Sold Out | -2.38M | -100.0% | $5.7M | 0.0% | 58 |
| D. E. Shaw & Co., Inc. Quant | New | +22.2K | — | $53.3K | 0.0% | 58 |
| Tang Capital Management Growth Healthcare | Sold Out | -399.7K | -100.0% | $959.3K | 0.0% | 56 |
| Squarepoint Ops LLC Quant | New | +11.7K | — | $28.2K | 0.0% | 54 |
| Gotham Asset Management, LLC Quant Value | New | +13.6K | — | $32.7K | 0.0% | 54 |
| Hudson Bay Capital Management Event | Sold Out | -152.6K | -100.0% | $366.3K | 0.0% | 53 |
| ExodusPoint Capital Management Long/Short Quant | Sold Out | -37.4K | -100.0% | $89.8K | 0.0% | 52 |
| Man Group Event Long/Short | Sold Out | -108.8K | -100.0% | $261.1K | 0.0% | 52 |
| Jain Global Long/Short Quant | Sold Out | -154.8K | -100.0% | $371.5K | 0.0% | 52 |
| Brevan Howard Capital Management Macro | Sold Out | -160.5K | -100.0% | $385.2K | 0.0% | 49 |
Most significant buyers
By move score, not size.
- D. E. Shaw & Co., Inc.
- Squarepoint Ops LLC
- Gotham Asset Management, LLC
- LMR Partners
- CITADEL ADVISORS LLC
Most significant sellers
By move score, not size.
- MARSHALL WACE, LLP
- Tang Capital Management
- Hudson Bay Capital Management
- ExodusPoint Capital Management
- Man Group
Hedge fund positions
| Fund | Tier | Shares | Previous | Change | Change % | Portfolio wt. | Action | Score |
|---|---|---|---|---|---|---|---|---|
| MARSHALL WACE, LLP | 2 | 0 | 2.4M | -2.38M | -100.0% | 0.0% | Sold Out | 58 |
| D. E. Shaw & Co., Inc. | 1 | 22.2K | 0 | +22.2K | — | 0.0% | New | 58 |
| Tang Capital Management | 2 | 0 | 399.7K | -399.7K | -100.0% | 0.0% | Sold Out | 56 |
| Squarepoint Ops LLC | 2 | 11.7K | 0 | +11.7K | — | 0.0% | New | 54 |
| Gotham Asset Management, LLC | 2 | 13.6K | 0 | +13.6K | — | 0.0% | New | 54 |
| Hudson Bay Capital Management | 3 | 0 | 152.6K | -152.6K | -100.0% | 0.0% | Sold Out | 53 |
| ExodusPoint Capital Management | 3 | 0 | 37.4K | -37.4K | -100.0% | 0.0% | Sold Out | 52 |
| Man Group | 3 | 0 | 108.8K | -108.8K | -100.0% | 0.0% | Sold Out | 52 |
| Jain Global | 3 | 0 | 154.8K | -154.8K | -100.0% | 0.0% | Sold Out | 52 |
| Brevan Howard Capital Management | 3 | 0 | 160.5K | -160.5K | -100.0% | 0.0% | Sold Out | 49 |
| MILLENNIUM MANAGEMENT LLC | 2 | 1.1M | 4.9M | -3.81M | -77.1% | 0.0% | Reduced | 47 |
| Quadrature Capital | 3 | 22.0K | 110.4K | -88.4K | -80.1% | 0.0% | Reduced | 42 |
| LMR Partners | 3 | 41.1K | 23.3K | +17.8K | +76.3% | 0.0% | Increased | 41 |
| CITADEL ADVISORS LLC | 1 | 1.6M | 1.1M | +506.3K | +46.2% | 0.0% | Increased | 40 |
| TWO SIGMA INVESTMENTS, LP | 2 | 643.4K | 1.2M | -556.2K | -46.4% | 0.0% | Reduced | 39 |
| RENAISSANCE TECHNOLOGIES LLC | 1 | 1.1M | 1.6M | -473.5K | -29.6% | 0.0% | Reduced | 37 |
| Winton Group | 4 | 43.2K | 25.5K | +17.7K | +69.4% | 0.0% | Increased | 35 |
| Sessa Capital | 2 | 19.0M | 17.9M | +1.05M | +5.8% | 0.8% | Increased | 34 |
| Point72 Asset Management, L.P. | 1 | 8.3M | 7.8M | +436.7K | +5.6% | 0.0% | Increased | 32 |
| Schonfeld Strategic Advisors | 3 | 49.4K | 75.1K | -25.7K | -34.2% | 0.0% | Reduced | 28 |
| Graham Capital Management | 3 | 23.5K | 34.0K | -10.5K | -30.8% | 0.0% | Reduced | 26 |
| AQR Capital Management | 3 | 75.2K | 96.2K | -21.0K | -21.8% | 0.0% | Reduced | 25 |
| ADAR1 Capital Management | 3 | 750.0K | 750.0K | 0 | +0.0% | 0.1% | Unchanged | 17 |
| Boothbay Fund Management | 4 | 44.3K | 44.3K | 0 | +0.0% | 0.0% | Unchanged | 13 |
Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeHedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.