LYEL Lyell Immunopharma, Inc.
Lyell Immunopharma, Inc. (LYEL) Institutional Ownership
What the institutions did with LYEL last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| ARCH Venture Management, LLC | 3.2M | 25.6% |
| GSK plc | 1.5M | 11.9% |
| VANGUARD CAPITAL MANAGEMENT LLC | 786.8K | 6.2% |
| Orland Properties Ltd | 754.7K | 6.0% |
| BlackRock, Inc. | 724.3K | 5.7% |
| Decheng Capital LLC | 692.1K | 5.5% |
| Almitas Capital LLC | 581.4K | 4.6% |
| Foresite Capital Management V, LLC | 476.4K | 3.8% |
| MILLENNIUM MANAGEMENT LLC | 367.5K | 2.9% |
| Opaleye Management Inc. | 344.0K | 2.7% |
| venBio Partners LLC | 337.7K | 2.7% |
| GEODE CAPITAL MANAGEMENT, LLC | 310.6K | 2.5% |
| Alphabet Inc. | 293.3K | 2.3% |
| STATE STREET CORP | 185.3K | 1.5% |
| HSG Holding Ltd | 152.3K | 1.2% |
| RENAISSANCE TECHNOLOGIES LLC | 130.2K | 1.0% |
| NORTHERN TRUST CORP | 118.5K | 0.9% |
| Qube Research & Technologies Ltd | 110.5K | 0.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 107.6K | 0.8% |
| MARSHALL WACE, LLP | 106.3K | 0.8% |
| Velan Capital Investment Management LP | 105.0K | 0.8% |
| VANGUARD FIDUCIARY TRUST CO | 93.1K | 0.7% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 91.9K | 0.7% |
| MIC Capital Management UK LLP | 87.0K | 0.7% |
| GOLDMAN SACHS GROUP INC | 86.8K | 0.7% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| Foresite Capital Management IV, LLC | Sold Out | 800.4K | 0 | -800.4K |
| BlackRock, Inc. | Increased | 191.8K | 724.3K | +532.5K |
| CITADEL ADVISORS LLC | Reduced | 381.5K | 18.7K | -362.8K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold Out | 310.2K | 0 | -310.2K |
| Opaleye Management Inc. | Increased | 79.1K | 344.0K | +264.9K |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 167.0K | 310.6K | +143.7K |
| STATE STREET CORP | Increased | 72.5K | 185.3K | +112.8K |
| MILLENNIUM MANAGEMENT LLC | Reduced | 458.9K | 367.5K | -91.4K |
| NORTHERN TRUST CORP | Increased | 30.3K | 118.5K | +88.2K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Increased | 23.0K | 91.9K | +68.9K |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 718.2K | 786.8K | +68.6K |
| ACADIAN ASSET MANAGEMENT LLC | New | 0 | 59.7K | +59.7K |
| Qube Research & Technologies Ltd | Increased | 55.1K | 110.5K | +55.4K |
| RBF Capital, LLC | Sold Out | 44.1K | 0 | -44.1K |
| MARSHALL WACE, LLP | Reduced | 148.5K | 106.3K | -42.2K |
| TWO SIGMA INVESTMENTS, LP | Increased | 11.6K | 52.9K | +41.3K |
| HRT FINANCIAL LP | New | 0 | 36.6K | +36.6K |
| GOLDMAN SACHS GROUP INC | Reduced | 114.5K | 86.8K | -27.7K |
| GSA CAPITAL PARTNERS LLP | New | 0 | 26.2K | +26.2K |
| Bank of New York Mellon Corp | New | 0 | 24.7K | +24.7K |
| Squarepoint Ops LLC | Increased | 19.3K | 42.3K | +23.0K |
| BANK OF AMERICA CORP /DE/ | Reduced | 33.3K | 10.9K | -22.5K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Increased | 86.0K | 107.6K | +21.6K |
| DIMENSIONAL FUND ADVISORS LP | Increased | 47.9K | 68.3K | +20.4K |
| Clearstead Advisors, LLC | Reduced | 39.9K | 20.0K | -20.0K |
| EntryPoint Capital, LLC | New | 0 | 19.4K | +19.4K |
| MORGAN STANLEY | Reduced | 56.2K | 37.1K | -19.1K |
| JANE STREET GROUP, LLC | Reduced | 63.9K | 46.0K | -17.9K |
| PRICE T ROWE ASSOCIATES INC /MD/ | Increased | 13.1K | 30.7K | +17.5K |
| Allspring Global Investments Holdings, LLC | New | 0 | 16.1K | +16.1K |
| RHUMBLINE ADVISERS | New | 0 | 15.5K | +15.5K |
| Invesco Ltd. | New | 0 | 13.9K | +13.9K |
| RENAISSANCE TECHNOLOGIES LLC | Increased | 116.4K | 130.2K | +13.8K |
| Nuveen, LLC | New | 0 | 12.6K | +12.6K |
| Walleye Capital LLC | Reduced | 22.2K | 10.5K | -11.8K |
| Graham Capital Management, L.P. | New | 0 | 11.6K | +11.6K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | New | 0 | 9.5K | +9.5K |
| DEUTSCHE BANK AG\ | New | 0 | 9.2K | +9.2K |
| AMERICAN CENTURY COMPANIES INC | Increased | 16.0K | 24.5K | +8.6K |
| WELLS FARGO & COMPANY/MN | Increased | 125 | 8.0K | +7.9K |
| VANGUARD FIDUCIARY TRUST CO | Increased | 86.9K | 93.1K | +6.2K |
| UBS Group AG | Reduced | 31.8K | 26.0K | -5.8K |
| BNP PARIBAS FINANCIAL MARKETS | Increased | 2.1K | 7.8K | +5.7K |
| Point72 Asset Management, L.P. | Increased | 21.3K | 26.1K | +4.8K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | New | 0 | 4.3K | +4.3K |
| NEW YORK STATE COMMON RETIREMENT FUND | New | 0 | 4.1K | +4.1K |
| Almitas Capital LLC | Increased | 577.8K | 581.4K | +3.6K |
| Police & Firemen's Retirement System of New Jersey | New | 0 | 3.4K | +3.4K |
| JPMORGAN CHASE & CO | Increased | 1.5K | 4.8K | +3.3K |
| BARCLAYS PLC | Increased | 1.7K | 4.7K | +3.0K |
| Velan Capital Investment Management LP | Increased | 102.0K | 105.0K | +3.0K |
| Susquehanna Portfolio Strategies, LLC | Reduced | 20.8K | 17.9K | -2.9K |
| Brevan Howard Capital Management LP | Reduced | 13.4K | 11.6K | -1.9K |
| Jump Financial, LLC | Increased | 20.1K | 22.0K | +1.8K |
| Legal & General Group Plc | New | 0 | 917 | +917 |
| CITIGROUP INC | Reduced | 5.9K | 5.0K | -887 |
| Ameritas Investment Partners, Inc. | New | 0 | 854 | +854 |
| Russell Investments Group, Ltd. | New | 0 | 752 | +752 |
| Foresite Capital Management V, LLC | Reduced | 477.1K | 476.4K | -692 |
| IFP Advisors, Inc | Sold Out | 648 | 0 | -648 |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.