MLYS Mineralys Therapeutics, Inc.

NASDAQ
$28.20

Mineralys Therapeutics, Inc. (MLYS) Insider Activity

What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.

Insider signal In line Selling ran in line with MLYS's own trailing one-year pace, with 29% of sale value under a prearranged plan.
Cluster activity 0 buyers in the last 30 days 0 buyers in the last 90 days 4 sellers in the last 90 days
Insiders buying
1
2 transactions
Insiders selling
7
83 transactions
Purchases
$8.8M
369,000 shares
Sales
$84.7M
2,176,105 shares
Net activity
-$76.0M
purchases less sales

How much of that selling was preplanned? 29% planned / 71% discretionary

10b5-1 plan sales $24.7M 60 transactions · 806,906 shares
Discretionary sales $60.1M 23 transactions · 1,369,199 shares

Largest single sale: $43.4M.

Where they traded

Buy Sell Dot area is proportional to transaction value.

Last open-market purchase: March 30, 2026 .

Recent open-market activity

Date Insider Role Action Shares Price Value Held after
Warren Eric Chief Commercial Officer Sell 10b5-1 7,437 $25.98 $193.2K 38,400 −16.2% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,170 $27.09 $58.8K 51,384 −4.1% of holding
Warren Eric Chief Commercial Officer Sell 10b5-1 7,438 $26.87 $199.9K 38,400 −16.2% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 416 $26.53 $11.0K 51,384 −0.8% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 6,349 $26.61 $169.0K 51,384 −11% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 14,058 $27.58 $387.7K 57,733 −19.6% of holding
Congleton Jon Chief Executive Officer Sell 10b5-1 10,700 $27.24 $291.4K 603,621 −1.7% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,171 $30.30 $65.8K 57,733 −3.6% of holding
Congleton Jon 2 fills Chief Executive Officer Sell 10b5-1 75,000 $26.14 $2.0M 631,321 −10.6% of holding
Warren Eric Chief Commercial Officer Sell 10b5-1 104,124 $25.90 $2.7M 38,400 −73.1% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 4,584 $25.00 $114.6K 57,095 −7.4% of holding
Karydas Daphne Director Sell 10b5-1 3,000 $25.00 $75.0K 6,200 −32.6% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 9,890 $23.81 $235.5K 57,095 −14.8% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 6,349 $23.93 $151.9K 63,443 −9.1% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,170 $25.00 $54.3K 63,443 −3.3% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 417 $27.55 $11.5K 63,443 −0.7% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 14,056 $28.58 $401.8K 63,443 −18.1% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 6,348 $29.36 $186.3K 69,792 −8.3% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,171 $29.71 $64.5K 69,792 −3% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 416 $31.33 $13.0K 69,792 −0.6% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 6,348 $27.66 $175.6K 69,792 −8.3% of holding
Congleton Jon Chief Executive Officer Sell 10b5-1 15,730 $26.83 $422.0K 689,321 −2.2% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 14,058 $26.54 $373.1K 76,140 −15.6% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,170 $27.38 $59.4K 76,140 −2.8% of holding
Congleton Jon 3 fills Chief Executive Officer Sell 10b5-1 75,000 $26.27 $2.0M 760,687 −9% of holding
Karydas Daphne Director Sell 10b5-1 3,000 $25.00 $75.0K 6,200 −32.6% of holding
Buy 58,300 $24.16 $1.4M 5,825,521
Buy 310,700 $23.67 $7.4M 5,767,221
Rodman David Malcom Chief Medical Officer Sell 10b5-1 417 $25.65 $10.7K 76,140 −0.5% of holding
Rodman David Malcom 3 fills Chief Medical Officer Sell 10b5-1 14,058 $26.26 $369.2K 79,472 −15% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 6,348 $27.37 $173.7K 82,489 −7.1% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,171 $26.84 $58.3K 82,489 −2.6% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 417 $27.59 $11.5K 44,089 −0.9% of holding
Rodman David Malcom 3 fills Chief Medical Officer Sell 10b5-1 14,055 $27.44 $385.7K 50,437 −21.8% of holding
Rodman David Malcom 2 fills Chief Medical Officer Sell 10b5-1 6,349 $28.99 $184.1K 50,958 −11.1% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,171 $30.21 $65.6K 50,437 −4.1% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 416 $32.10 $13.4K 50,437 −0.8% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 11,367 $32.61 $370.6K 50,437 −18.4% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 7,709 $32.75 $252.5K 61,804 −11.1% of holding
Congleton Jon 2 fills Chief Executive Officer Sell 10b5-1 16,236 $32.62 $529.6K 646,268 −2.5% of holding
Levy Adam Scott CFO and Secretary Sell 10b5-1 10,758 $32.14 $345.7K 8,638 −55.5% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 6,348 $32.32 $205.1K 61,804 −9.3% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 2,170 $33.27 $72.2K 61,804 −3.4% of holding
Rodman David Malcom 2 fills Chief Medical Officer Sell 10b5-1 192,715 $35.02 $6.7M 115,274 −62.6% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 70,037 $35.87 $2.5M 69,188 −50.3% of holding
Sell 1,000,000 $43.35 $43.4M 7,903,838 −11.2% of holding
Karydas Daphne 2 fills Director Sell 15,000 $45.99 $689.8K 4,885 −75.4% of holding
Gold Alexander M Director Sell 12,742 $46.50 $592.5K None left
Gold Alexander M 2 fills Director Sell 6,933 $46.72 $323.9K 1,933 −78.2% of holding
Congleton Jon 6 fills Chief Executive Officer Sell 200,000 $45.44 $9.1M 818,499 −19.6% of holding
Levy Adam Scott 9 fills CFO and Secretary Sell 119,524 $44.88 $5.4M 137,905 −46.4% of holding
Gold Alexander M 2 fills Director Sell 15,000 $43.98 $659.7K 5,000 −75% of holding
Rodman David Malcom Chief Medical Officer Sell 10b5-1 10,369 $43.01 $446.0K 71,155 −12.7% of holding
Congleton Jon 2 fills Chief Executive Officer Sell 10b5-1 15,100 $42.67 $644.3K 832,857 −1.8% of holding
Levy Adam Scott 2 fills CFO and Secretary Sell 10b5-1 10,758 $42.01 $452.0K 120,257 −8.2% of holding
Rodman David Malcom 2 fills Chief Medical Officer Sell 10b5-1 11,367 $36.00 $409.3K 83,589 −12% of holding

Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.