PYXS Pyxis Oncology, Inc.

NASDAQ
$3.08

Pyxis Oncology, Inc. (PYXS) Institutional Ownership

What the institutions did with PYXS last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
86
filed a 13F this quarter
Managers holding
76
-1 on the quarter
Buyers
33
9 opened new
Sellers
34
10 sold out entirely
Buyer share
49.3%
of managers who traded it
Breadth
-1.5
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
GordonMD Global Investments LP 10.0M 29.4%
Pfizer Inc 7.0M 20.6%
Laurion Capital Management LP 4.9M 14.4%
VANGUARD CAPITAL MANAGEMENT LLC 2.1M 6.1%
Atle Fund Management AB 966.5K 2.8%
BlackRock, Inc. 867.9K 2.5%
Palo Alto Investors LP 864.3K 2.5%
MARSHALL WACE, LLP 830.5K 2.4%
RENAISSANCE TECHNOLOGIES LLC 772.2K 2.3%
GEODE CAPITAL MANAGEMENT, LLC 591.8K 1.7%
Woodline Partners LP 524.0K 1.5%
683 Capital Management, LLC 459.4K 1.3%
JACOBS LEVY EQUITY MANAGEMENT, INC 428.6K 1.3%
Longaeva Partners L.P. 353.6K 1.0%
Decheng Capital LLC 326.8K 1.0%
VANGUARD FIDUCIARY TRUST CO 303.0K 0.9%
JANE STREET GROUP, LLC 290.1K 0.8%
STATE STREET CORP 248.8K 0.7%
MILLENNIUM MANAGEMENT LLC 233.0K 0.7%
UBS Group AG 155.2K 0.5%
Bank of New York Mellon Corp 134.0K 0.4%
ACADIAN ASSET MANAGEMENT LLC 126.8K 0.4%
NORTHERN TRUST CORP 124.0K 0.4%
NewEdge Wealth, LLC 116.0K 0.3%
XTX Topco Ltd 110.9K 0.3%

Largest changes

Manager Action Previous Current Change
GordonMD Global Investments LP Increased 4.1M 10.0M +5.9M
Atle Fund Management AB Increased 197.0K 966.5K +769.4K
Woodline Partners LP New 0 524.0K +524.0K
MARSHALL WACE, LLP Increased 354.4K 830.5K +476.1K
683 Capital Management, LLC Reduced 896.3K 459.4K -436.9K
MILLENNIUM MANAGEMENT LLC Reduced 397.6K 233.0K -164.6K
Longaeva Partners L.P. Reduced 503.2K 353.6K -149.6K
Palo Alto Investors LP Reduced 1.0M 864.3K -146.2K
RENAISSANCE TECHNOLOGIES LLC Reduced 888.7K 772.2K -116.4K
UBS Group AG Reduced 254.1K 155.2K -98.9K
Laurion Capital Management LP Reduced 5.0M 4.9M -96.4K
XTX Topco Ltd Reduced 200.1K 110.9K -89.2K
BlackRock, Inc. Increased 788.8K 867.9K +79.1K
PANAGORA ASSET MANAGEMENT INC Sold Out 69.4K 0 -69.4K
BANK OF AMERICA CORP /DE/ Increased 16.8K 80.5K +63.7K
MYDA Advisors LLC New 0 50.0K +50.0K
TORONTO DOMINION BANK Sold Out 50.0K 0 -50.0K
Quadrature Capital Ltd New 0 47.1K +47.1K
BARCLAYS PLC Reduced 49.8K 4.7K -45.2K
Verdad Advisers, LP New 0 44.9K +44.9K
VANGUARD CAPITAL MANAGEMENT LLC Increased 2.0M 2.1M +42.5K
SUSQUEHANNA INTERNATIONAL GROUP, LLP Sold Out 41.2K 0 -41.2K
Qube Research & Technologies Ltd Increased 11.3K 49.9K +38.6K
SIMPLEX TRADING, LLC Increased 253 37.9K +37.6K
Walleye Capital LLC New 0 36.8K +36.8K

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.