SION Sionna Therapeutics, Inc.
Sionna Therapeutics, Inc. (SION) Hedge Fund Activity
This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.
Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.
Most significant moves
Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.
| Fund | Action | Shares changed | Change | Est. value | Portfolio wt. | Score |
|---|---|---|---|---|---|---|
| D. E. Shaw & Co., Inc. Quant | New | +101.6K | — | $4.5M | 0.0% | 60 |
| TWO SIGMA INVESTMENTS, LP Quant | Sold Out | -5.5K | -100.0% | $241.9K | 0.0% | 57 |
| MARSHALL WACE, LLP Long/Short | New | +12.6K | — | $554.2K | 0.0% | 56 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Increased | +1.45M | +966.7% | $63.8M | 0.1% | 56 |
| Quadrature Capital Quant | New | +26.0K | — | $1.1M | 0.0% | 55 |
| Tudor Investment Corporation Macro | New | +22.6K | — | $993.1K | 0.0% | 54 |
| Hudson Bay Capital Management Event | Sold Out | -6.2K | -100.0% | $271.9K | 0.0% | 53 |
| Trexquant Investment Quant | New | +23.8K | — | $1.0M | 0.0% | 53 |
| MILLENNIUM MANAGEMENT LLC | Increased | +136.1K | +96.8% | $6.0M | 0.0% | 52 |
| OrbiMed Advisors Growth Healthcare | Reduced | -974.8K | -27.6% | $42.9M | 2.1% | 52 |
Most significant buyers
By move score, not size.
- D. E. Shaw & Co., Inc.
- MARSHALL WACE, LLP
- ADAGE CAPITAL PARTNERS GP, L.L.C.
- Quadrature Capital
- Tudor Investment Corporation
Most significant sellers
By move score, not size.
- TWO SIGMA INVESTMENTS, LP
- Hudson Bay Capital Management
- OrbiMed Advisors
- ExodusPoint Capital Management
- Point72 Asset Management, L.P.
Hedge fund positions
| Fund | Tier | Shares | Previous | Change | Change % | Portfolio wt. | Action | Score |
|---|---|---|---|---|---|---|---|---|
| D. E. Shaw & Co., Inc. | 1 | 101.6K | 0 | +101.6K | — | 0.0% | New | 60 |
| TWO SIGMA INVESTMENTS, LP | 2 | 0 | 5.5K | -5.5K | -100.0% | 0.0% | Sold Out | 57 |
| MARSHALL WACE, LLP | 2 | 12.6K | 0 | +12.6K | — | 0.0% | New | 56 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2 | 1.6M | 150.0K | +1.45M | +966.7% | 0.1% | Increased | 56 |
| Quadrature Capital | 3 | 26.0K | 0 | +26.0K | — | 0.0% | New | 55 |
| Tudor Investment Corporation | 2 | 22.6K | 0 | +22.6K | — | 0.0% | New | 54 |
| Hudson Bay Capital Management | 3 | 0 | 6.2K | -6.2K | -100.0% | 0.0% | Sold Out | 53 |
| Trexquant Investment | 3 | 23.8K | 0 | +23.8K | — | 0.0% | New | 53 |
| MILLENNIUM MANAGEMENT LLC | 2 | 276.7K | 140.6K | +136.1K | +96.8% | 0.0% | Increased | 52 |
| OrbiMed Advisors | 2 | 2.6M | 3.5M | -974.8K | -27.6% | 2.1% | Reduced | 52 |
| ExodusPoint Capital Management | 3 | 0 | 7.2K | -7.2K | -100.0% | 0.0% | Sold Out | 52 |
| Jain Global | 3 | 4.8K | 0 | +4.8K | — | 0.0% | New | 52 |
| Qube Research & Technologies Ltd | 2 | 140.3K | 42.2K | +98.1K | +232.2% | 0.0% | Increased | 51 |
| Engineers Gate | 4 | 15.6K | 0 | +15.6K | — | 0.0% | New | 48 |
| Walleye Capital | 3 | 97.3K | 15.1K | +82.3K | +544.8% | 0.0% | Increased | 47 |
| Point72 Asset Management, L.P. | 1 | 49.3K | 136.5K | -87.2K | -63.9% | 0.0% | Reduced | 46 |
| Perceptive Advisors | 1 | 905.0K | 658.4K | +246.6K | +37.4% | 0.6% | Increased | 46 |
| Deerfield Management | 1 | 680.9K | 970.6K | -289.7K | -29.8% | 0.4% | Reduced | 44 |
| Integral Health Asset Management | 2 | 75.0K | 50.0K | +25.0K | +50.0% | 0.1% | Increased | 40 |
| Soleus Capital Management | 2 | 177.7K | 293.5K | -115.8K | -39.5% | 0.3% | Reduced | 40 |
| Squarepoint Ops LLC | 2 | 5.4K | 15.2K | -9.8K | -64.4% | 0.0% | Reduced | 40 |
| Quantbot Technologies | 4 | 1.8K | 178 | +1.6K | +922.5% | 0.0% | Increased | 39 |
| CITADEL ADVISORS LLC | 1 | 1.1M | 1.2M | -19.3K | -1.7% | 0.0% | Reduced | 27 |
| RA Capital Management | 1 | 9.9M | 9.9M | 0 | +0.0% | 3.8% | Unchanged | 46 |
| VIKING GLOBAL INVESTORS LP | 1 | 3.2M | 3.2M | 0 | +0.0% | 0.4% | Unchanged | 27 |
| Baker Bros. Advisors | 1 | 400.0K | 400.0K | 0 | +0.0% | 0.1% | Unchanged | 25 |
| Alyeska Investment Group, L.P. | 2 | 136.2K | 136.2K | 0 | +0.0% | 0.0% | Unchanged | 20 |
| Rock Springs Capital Management | 3 | 99.4K | 99.4K | 0 | +0.0% | 0.2% | Unchanged | 18 |
Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeHedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.