SLN Silence Therapeutics plc
Silence Therapeutics plc (SLN) Institutional Ownership
What the institutions did with SLN last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| Siren, L.L.C. | 3.3M | 14.0% |
| TCG Crossover Management, LLC | 3.0M | 12.9% |
| Nantahala Capital Management, LLC | 2.7M | 11.4% |
| Redmile Group, LLC | 2.2M | 9.2% |
| CITADEL ADVISORS LLC | 1.3M | 5.6% |
| Nextech Invest, Ltd. | 952.4K | 4.0% |
| MILLENNIUM MANAGEMENT LLC | 909.3K | 3.9% |
| Ikarian Capital, LLC | 830.8K | 3.5% |
| Tetragon Partners GP Ltd | 764.3K | 3.2% |
| Soleus Capital Management, L.P. | 630.0K | 2.7% |
| Balyasny Asset Management L.P. | 611.0K | 2.6% |
| 5AM Venture Management, LLC | 476.2K | 2.0% |
| GREAT POINT PARTNERS LLC | 450.0K | 1.9% |
| MORGAN STANLEY | 403.2K | 1.7% |
| AMERIPRISE FINANCIAL INC | 370.1K | 1.6% |
| JANE STREET GROUP, LLC | 369.2K | 1.6% |
| ADAR1 Capital Management, LLC | 338.4K | 1.4% |
| SummitTX Capital, L.P. | 326.6K | 1.4% |
| Schonfeld Strategic Advisors LLC | 269.3K | 1.1% |
| UBS Group AG | 243.2K | 1.0% |
| BlackRock, Inc. | 219.9K | 0.9% |
| BANK OF MONTREAL /CAN/ | 201.7K | 0.9% |
| BOOTHBAY FUND MANAGEMENT, LLC | 198.3K | 0.8% |
| Propel Bio Management, LLC | 191.7K | 0.8% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 184.5K | 0.8% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| Soleus Capital Management, L.P. | New | 0 | 630.0K | +630.0K |
| Balyasny Asset Management L.P. | New | 0 | 611.0K | +611.0K |
| GREAT POINT PARTNERS LLC | Reduced | 1.0M | 450.0K | -570.5K |
| Nantahala Capital Management, LLC | Increased | 2.1M | 2.7M | +546.7K |
| Siren, L.L.C. | Increased | 2.9M | 3.3M | +400.0K |
| AMERIPRISE FINANCIAL INC | New | 0 | 370.1K | +370.1K |
| MORGAN STANLEY | Increased | 65.5K | 403.2K | +337.7K |
| SummitTX Capital, L.P. | New | 0 | 326.6K | +326.6K |
| Jones Hill Capital LP | Sold Out | 301.6K | 0 | -301.6K |
| SG Americas Securities, LLC | Reduced | 286.7K | 12.1K | -274.6K |
| Schonfeld Strategic Advisors LLC | New | 0 | 269.3K | +269.3K |
| JANE STREET GROUP, LLC | Increased | 100.9K | 369.2K | +268.2K |
| Propel Bio Management, LLC | New | 0 | 191.7K | +191.7K |
| FRED ALGER MANAGEMENT, LLC | New | 0 | 177.0K | +177.0K |
| ADAR1 Capital Management, LLC | Increased | 172.2K | 338.4K | +166.2K |
| MILLENNIUM MANAGEMENT LLC | Reduced | 1.1M | 909.3K | -164.9K |
| Caption Management, LLC | New | 0 | 162.5K | +162.5K |
| Tetragon Partners GP Ltd | Increased | 630.2K | 764.3K | +134.1K |
| Point72 Asset Management, L.P. | Sold Out | 119.7K | 0 | -119.7K |
| Quadrature Capital Ltd | New | 0 | 118.1K | +118.1K |
| TWO SIGMA INVESTMENTS, LP | Increased | 16.2K | 121.0K | +104.8K |
| GOLDMAN SACHS GROUP INC | Increased | 52.5K | 155.9K | +103.4K |
| MARSHALL WACE, LLP | Reduced | 169.6K | 72.0K | -97.6K |
| Seven Fleet Capital Management LP | Reduced | 156.8K | 60.1K | -96.7K |
| CITADEL ADVISORS LLC | Increased | 1.2M | 1.3M | +94.8K |
| Ishara Investments LP | Reduced | 140.5K | 55.4K | -85.2K |
| Birchview Capital, LP | New | 0 | 71.2K | +71.2K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Increased | 115.3K | 184.5K | +69.2K |
| Qube Research & Technologies Ltd | Increased | 104.6K | 163.9K | +59.4K |
| Ikarian Capital, LLC | Reduced | 865.8K | 830.8K | -35.0K |
| Squarepoint Ops LLC | Increased | 89.5K | 115.9K | +26.4K |
| Virtu Financial LLC | New | 0 | 25.6K | +25.6K |
| Trexquant Investment LP | New | 0 | 23.8K | +23.8K |
| Verdad Advisers, LP | New | 0 | 20.4K | +20.4K |
| Scientech Research LLC | New | 0 | 19.1K | +19.1K |
| HRT FINANCIAL LP | Increased | 12.0K | 30.7K | +18.8K |
| RENAISSANCE TECHNOLOGIES LLC | New | 0 | 16.9K | +16.9K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | New | 0 | 16.3K | +16.3K |
| Persistent Asset Partners Ltd | New | 0 | 15.2K | +15.2K |
| BlackRock, Inc. | Increased | 204.8K | 219.9K | +15.1K |
| AXQ CAPITAL, LP | New | 0 | 12.6K | +12.6K |
| CITIGROUP INC | Increased | 1.8K | 13.2K | +11.4K |
| BNP PARIBAS FINANCIAL MARKETS | Increased | 147.7K | 159.0K | +11.3K |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | 209.1K | 198.3K | -10.7K |
| Dynamic Technology Lab Private Ltd | Sold Out | 10.5K | 0 | -10.5K |
| CenterBook Partners LP | New | 0 | 10.4K | +10.4K |
| RAYMOND JAMES FINANCIAL INC | Reduced | 25.0K | 15.0K | -10.0K |
| ACADIAN ASSET MANAGEMENT LLC | Increased | 4.8K | 11.8K | +7.0K |
| BANK OF AMERICA CORP /DE/ | Reduced | 29.8K | 25.3K | -4.5K |
| UBS Group AG | Reduced | 246.9K | 243.2K | -3.8K |
| JPMORGAN CHASE & CO | Reduced | 7.6K | 3.9K | -3.8K |
| GAMMA Investing LLC | Increased | 9.4K | 11.1K | +1.7K |
| XTX Topco Ltd | Increased | 106.0K | 107.6K | +1.6K |
| BANK OF MONTREAL /CAN/ | Reduced | 202.9K | 201.7K | -1.2K |
| Rialto Wealth Management, LLC | New | 0 | 1.0K | +1.0K |
| China Universal Asset Management Co., Ltd. | Reduced | 8.3K | 7.5K | -860 |
| Tower Research Capital LLC (TRC) | Reduced | 2.3K | 1.6K | -674 |
| SIMPLEX TRADING, LLC | Sold Out | 612 | 0 | -612 |
| BARCLAYS PLC | Increased | 2.9K | 3.4K | +481 |
| Mirae Asset Global Investments Co., Ltd. | Reduced | 2.5K | 2.1K | -349 |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.