SPRB Spruce Biosciences, Inc.
Spruce Biosciences, Inc. (SPRB) Institutional Ownership
What the institutions did with SPRB last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeLargest holders
| Manager | Shares | % of reported |
|---|---|---|
| AIGH Capital Management LLC | 250.0K | 12.5% |
| ORBIMED ADVISORS LLC | 200.0K | 10.0% |
| BlackRock, Inc. | 187.8K | 9.4% |
| MILLENNIUM MANAGEMENT LLC | 161.0K | 8.0% |
| Ikarian Capital, LLC | 121.4K | 6.1% |
| VANGUARD CAPITAL MANAGEMENT LLC | 119.3K | 6.0% |
| Alyeska Investment Group, L.P. | 81.7K | 4.1% |
| GEODE CAPITAL MANAGEMENT, LLC | 70.5K | 3.5% |
| ADAR1 Capital Management, LLC | 67.7K | 3.4% |
| Cable Car Capital, LP | 60.0K | 3.0% |
| CITADEL ADVISORS LLC | 51.9K | 2.6% |
| STATE STREET CORP | 50.5K | 2.5% |
| BOOTHBAY FUND MANAGEMENT, LLC | 42.1K | 2.1% |
| STEMPOINT CAPITAL LP | 41.4K | 2.1% |
| Eversept Partners, LP | 40.0K | 2.0% |
| Carlyle Group Inc. | 38.6K | 1.9% |
| GOLDMAN SACHS GROUP INC | 32.3K | 1.6% |
| Affinity Asset Advisors, LLC | 30.0K | 1.5% |
| DIADEMA PARTNERS LP | 30.0K | 1.5% |
| Stonepine Capital Management, LLC | 28.8K | 1.4% |
| Point72 Asset Management, L.P. | 28.3K | 1.4% |
| Quinn Opportunity Partners LLC | 26.8K | 1.3% |
| UBS Group AG | 23.4K | 1.2% |
| ExodusPoint Capital Management, LP | 22.0K | 1.1% |
| NORTHERN TRUST CORP | 21.1K | 1.1% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| AIGH Capital Management LLC | New | 0 | 250.0K | +250.0K |
| ORBIMED ADVISORS LLC | New | 0 | 200.0K | +200.0K |
| BlackRock, Inc. | Increased | 16.9K | 187.8K | +170.9K |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 18.3K | 119.3K | +101.0K |
| Cable Car Capital, LP | New | 0 | 60.0K | +60.0K |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 12.9K | 70.5K | +57.7K |
| MILLENNIUM MANAGEMENT LLC | Increased | 111.9K | 161.0K | +49.1K |
| WELLINGTON MANAGEMENT GROUP LLP | Sold Out | 48.8K | 0 | -48.8K |
| STATE STREET CORP | Increased | 5.4K | 50.5K | +45.1K |
| Eversept Partners, LP | New | 0 | 40.0K | +40.0K |
| Affinity Asset Advisors, LLC | New | 0 | 30.0K | +30.0K |
| Alyeska Investment Group, L.P. | Increased | 51.7K | 81.7K | +30.0K |
| Stonepine Capital Management, LLC | New | 0 | 28.8K | +28.8K |
| STEMPOINT CAPITAL LP | Increased | 12.7K | 41.4K | +28.7K |
| Point72 Asset Management, L.P. | New | 0 | 28.3K | +28.3K |
| Balyasny Asset Management L.P. | Reduced | 40.0K | 12.1K | -27.9K |
| GOLDMAN SACHS GROUP INC | Increased | 5.5K | 32.3K | +26.8K |
| NORTHERN TRUST CORP | New | 0 | 21.1K | +21.1K |
| DIADEMA PARTNERS LP | Increased | 10.0K | 30.0K | +20.0K |
| Knott David M Jr | New | 0 | 20.0K | +20.0K |
| Rosalind Advisors, Inc. | New | 0 | 20.0K | +20.0K |
| UBS Group AG | Increased | 3.9K | 23.4K | +19.5K |
| AMERIPRISE FINANCIAL INC | New | 0 | 18.8K | +18.8K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | 0 | 18.5K | +18.5K |
| CITADEL ADVISORS LLC | Reduced | 70.0K | 51.9K | -18.1K |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.