VRTX Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals Incorporated (VRTX) Hedge Fund Activity
This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.
Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.
Most significant moves
Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.
| Fund | Action | Shares changed | Change | Est. value | Portfolio wt. | Score |
|---|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | New | +2.6K | — | $1.3M | 0.0% | 61 |
| Hudson Bay Capital Management Event | Increased | +345.4K | +767.6% | $171.6M | 1.1% | 61 |
| MILLENNIUM MANAGEMENT LLC | Increased | +437.6K | +1419.7% | $217.4M | 0.2% | 60 |
| D. E. Shaw & Co., Inc. Quant | Reduced | -245.9K | -98.8% | $122.1M | 0.0% | 60 |
| Caxton Associates Macro | Sold Out | -36.0K | -100.0% | $17.9M | 0.0% | 59 |
| Balyasny Asset Management L.P. | Increased | +104.9K | +261.3% | $52.1M | 0.1% | 58 |
| Tudor Investment Corporation Macro | New | +30.2K | — | $15.0M | 0.1% | 58 |
| Quadrature Capital Quant | New | +46.9K | — | $23.3M | 0.2% | 58 |
| ADAR1 Capital Management Long/Short Growth | Sold Out | -15.1K | -100.0% | $7.5M | 0.0% | 57 |
| Qube Research & Technologies Ltd Quant | Sold Out | -4.0K | -100.0% | $2.0M | 0.0% | 57 |
Most significant buyers
By move score, not size.
- Point72 Asset Management, L.P.
- Hudson Bay Capital Management
- MILLENNIUM MANAGEMENT LLC
- Balyasny Asset Management L.P.
- Tudor Investment Corporation
Most significant sellers
By move score, not size.
- D. E. Shaw & Co., Inc.
- Caxton Associates
- ADAR1 Capital Management
- Qube Research & Technologies Ltd
- ExodusPoint Capital Management
Hedge fund positions
| Fund | Tier | Shares | Previous | Change | Change % | Portfolio wt. | Action | Score |
|---|---|---|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 1 | 2.6K | 0 | +2.6K | — | 0.0% | New | 61 |
| Hudson Bay Capital Management | 3 | 390.4K | 45.0K | +345.4K | +767.6% | 1.1% | Increased | 61 |
| MILLENNIUM MANAGEMENT LLC | 2 | 468.4K | 30.8K | +437.6K | +1419.7% | 0.2% | Increased | 60 |
| D. E. Shaw & Co., Inc. | 1 | 3.1K | 249.0K | -245.9K | -98.8% | 0.0% | Reduced | 60 |
| Caxton Associates | 3 | 0 | 36.0K | -36.0K | -100.0% | 0.0% | Sold Out | 59 |
| Balyasny Asset Management L.P. | 2 | 145.0K | 40.1K | +104.9K | +261.3% | 0.1% | Increased | 58 |
| Tudor Investment Corporation | 2 | 30.2K | 0 | +30.2K | — | 0.1% | New | 58 |
| Quadrature Capital | 3 | 46.9K | 0 | +46.9K | — | 0.2% | New | 58 |
| ADAR1 Capital Management | 3 | 0 | 15.1K | -15.1K | -100.0% | 0.0% | Sold Out | 57 |
| Qube Research & Technologies Ltd | 2 | 0 | 4.0K | -4.0K | -100.0% | 0.0% | Sold Out | 57 |
| ExodusPoint Capital Management | 3 | 0 | 22.4K | -22.4K | -100.0% | 0.0% | Sold Out | 57 |
| Weiss Asset Management | 2 | 4.7K | 0 | +4.7K | — | 0.0% | New | 56 |
| Magnetar Capital | 2 | 0 | 1.7K | -1.7K | -100.0% | 0.0% | Sold Out | 54 |
| J. Goldman & Co. | 3 | 12.3K | 0 | +12.3K | — | 0.2% | New | 53 |
| AQR Capital Management | 3 | 616.2K | 171.0K | +445.1K | +260.3% | 0.1% | Increased | 53 |
| Schonfeld Strategic Advisors | 3 | 2.9K | 0 | +2.9K | — | 0.0% | New | 53 |
| Trexquant Investment | 3 | 0 | 15.2K | -15.2K | -100.0% | 0.0% | Sold Out | 53 |
| MARSHALL WACE, LLP | 2 | 543.9K | 317.1K | +226.8K | +71.5% | 0.3% | Increased | 53 |
| CenterBook Partners | 4 | 3.7K | 0 | +3.7K | — | 0.1% | New | 51 |
| Centiva Capital | 4 | 0 | 2.1K | -2.1K | -100.0% | 0.0% | Sold Out | 50 |
| Cinctive Capital Management | 3 | 26.7K | 5.0K | +21.7K | +429.1% | 0.5% | Increased | 50 |
| Parallax Volatility Advisers | 3 | 599 | 0 | +599 | — | 0.0% | New | 50 |
| Alphadyne Asset Management | 3 | 73 | 8.9K | -8.8K | -99.2% | 0.0% | Reduced | 50 |
| Capula Management | 2 | 509 | 247 | +262 | +106.1% | 0.0% | Increased | 50 |
| Walleye Capital | 3 | 335 | 30.8K | -30.4K | -98.9% | 0.0% | Reduced | 49 |
| Holocene Advisors, LP | 2 | 12.4K | 67.6K | -55.2K | -81.7% | 0.0% | Reduced | 49 |
| Jain Global | 3 | 9.5K | 4.7K | +4.9K | +103.7% | 0.1% | Increased | 48 |
| Caption Management | 3 | 9.4K | 200 | +9.2K | +4600.0% | 0.2% | Increased | 47 |
| CITADEL ADVISORS LLC | 1 | 510.4K | 339.3K | +171.1K | +50.4% | 0.2% | Increased | 46 |
| Brevan Howard Capital Management | 3 | 17.6K | 3.2K | +14.5K | +459.1% | 0.2% | Increased | 46 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2 | 394.0K | 252.0K | +142.0K | +56.3% | 0.3% | Increased | 46 |
| Quantbot Technologies | 4 | 0 | 555 | -555 | -100.0% | 0.0% | Sold Out | 45 |
| Squarepoint Ops LLC | 2 | 12.0K | 6.8K | +5.3K | +78.2% | 0.0% | Increased | 45 |
| Voleon Capital Management | 3 | 1.3K | 513 | +764 | +148.9% | 0.0% | Increased | 45 |
| Boothbay Fund Management | 4 | 6.2K | 1.3K | +4.9K | +367.7% | 0.1% | Increased | 45 |
| Y-Intercept | 4 | 8.3K | 35.8K | -27.5K | -76.9% | 0.1% | Reduced | 42 |
| RENAISSANCE TECHNOLOGIES LLC | 1 | 320.0K | 421.7K | -101.7K | -24.1% | 0.2% | Reduced | 41 |
| Verition Fund Management | 2 | 429 | 1.4K | -980 | -69.6% | 0.0% | Reduced | 40 |
| Capstone Investment Advisors | 3 | 1.4K | 3.9K | -2.4K | -62.8% | 0.0% | Reduced | 40 |
| Capital Fund Management | 3 | 71.1K | 122.9K | -51.8K | -42.2% | 0.3% | Reduced | 39 |
| Engineers Gate | 4 | 3.1K | 13.8K | -10.8K | -77.8% | 0.0% | Reduced | 39 |
| Bridgewater Associates | 1 | 10.9K | 13.4K | -2.5K | -18.7% | 0.0% | Reduced | 37 |
| LMR Partners | 3 | 10.0K | 19.9K | -9.9K | -49.8% | 0.1% | Reduced | 37 |
| TWO SIGMA INVESTMENTS, LP | 2 | 285.0K | 378.1K | -93.1K | -24.6% | 0.1% | Reduced | 37 |
| Man Group | 3 | 139.2K | 236.8K | -97.6K | -41.2% | 0.1% | Reduced | 36 |
| Edgestream Partners | 4 | 1.5K | 3.3K | -1.7K | -52.5% | 0.0% | Reduced | 31 |
| Woodline Partners LP | 2 | 140.3K | 135.0K | +5.3K | +4.0% | 0.2% | Increased | 27 |
| Gotham Asset Management, LLC | 2 | 19.0K | 20.9K | -1.9K | -9.1% | 0.0% | Reduced | 26 |
| Graham Capital Management | 3 | 685 | 686 | -1 | -0.1% | 0.0% | Reduced | 18 |
| Integral Health Asset Management | 2 | 40.0K | 40.0K | 0 | +0.0% | 0.8% | Unchanged | 25 |
Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeHedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.