XLO Xilio Therapeutics, Inc.
Xilio Therapeutics, Inc. (XLO) Institutional Ownership
What the institutions did with XLO last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 664.0K | 19.5% |
| GILEAD SCIENCES, INC. | 650.4K | 19.1% |
| ORBIMED ADVISORS LLC | 592.3K | 17.4% |
| Frazier Life Sciences Management, L.P. | 422.5K | 12.4% |
| Stonepine Capital Management, LLC | 226.0K | 6.6% |
| VANGUARD CAPITAL MANAGEMENT LLC | 178.5K | 5.2% |
| Sio Capital Management, LLC | 152.5K | 4.5% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 111.5K | 3.3% |
| Merck & Co., Inc. | 106.0K | 3.1% |
| RENAISSANCE TECHNOLOGIES LLC | 64.2K | 1.9% |
| MORGAN STANLEY | 57.0K | 1.7% |
| GEODE CAPITAL MANAGEMENT, LLC | 39.1K | 1.1% |
| CITADEL ADVISORS LLC | 26.0K | 0.8% |
| VANGUARD FIDUCIARY TRUST CO | 22.6K | 0.7% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 17.5K | 0.5% |
| TWO SIGMA INVESTMENTS, LP | 14.5K | 0.4% |
| Velan Capital Investment Management LP | 14.3K | 0.4% |
| GSA CAPITAL PARTNERS LLP | 13.6K | 0.4% |
| STATE STREET CORP | 13.3K | 0.4% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 11.6K | 0.3% |
| BlackRock, Inc. | 8.8K | 0.3% |
| Steward Partners Investment Advisory, LLC | 714 | 0.0% |
| SECURITY NATIONAL BANK OF SIOUX CITY IOWA /IA/ | 321 | 0.0% |
| BARCLAYS PLC | 115 | 0.0% |
| Key Financial Inc | 59 | 0.0% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | New | 0 | 592.3K | +592.3K |
| Stonepine Capital Management, LLC | Increased | 64.2K | 226.0K | +161.8K |
| Caligan Partners LP | Sold Out | 112.1K | 0 | -112.1K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | 0 | 111.5K | +111.5K |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 123.7K | 178.5K | +54.9K |
| FMR LLC | Sold Out | 36.6K | 0 | -36.6K |
| CITADEL ADVISORS LLC | New | 0 | 26.0K | +26.0K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | New | 0 | 17.5K | +17.5K |
| RENAISSANCE TECHNOLOGIES LLC | Increased | 49.6K | 64.2K | +14.6K |
| TWO SIGMA INVESTMENTS, LP | New | 0 | 14.5K | +14.5K |
| Ghisallo Capital Management LLC | Sold Out | 13.8K | 0 | -13.8K |
| PRELUDE CAPITAL MANAGEMENT, LLC | New | 0 | 11.6K | +11.6K |
| BlackRock, Inc. | New | 0 | 8.8K | +8.8K |
| VANGUARD FIDUCIARY TRUST CO | Reduced | 28.5K | 22.6K | -5.9K |
| UBS Group AG | Reduced | 4.0K | 14 | -4.0K |
| GSA CAPITAL PARTNERS LLP | Reduced | 16.9K | 13.6K | -3.4K |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 37.2K | 39.1K | +1.9K |
| Steward Partners Investment Advisory, LLC | New | 0 | 714 | +714 |
| MORGAN STANLEY | Reduced | 57.5K | 57.0K | -539 |
| SECURITY NATIONAL BANK OF SIOUX CITY IOWA /IA/ | New | 0 | 321 | +321 |
| JPMORGAN CHASE & CO | Sold Out | 240 | 0 | -240 |
| Vanguard Global Advisers, LLC | Sold Out | 210 | 0 | -210 |
| BARCLAYS PLC | New | 0 | 115 | +115 |
| ROYAL BANK OF CANADA | Sold Out | 91 | 0 | -91 |
| JONES FINANCIAL COMPANIES LLLP | New | 0 | 29 | +29 |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.