XLO Xilio Therapeutics, Inc.

NASDAQ
$9.01

Xilio Therapeutics, Inc. (XLO) Institutional Ownership

What the institutions did with XLO last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
32
filed a 13F this quarter
Managers holding
26
+4 on the quarter
Buyers
14
10 opened new
Sellers
10
6 sold out entirely
Buyer share
58.3%
of managers who traded it
Breadth
+16.7
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
Bain Capital Life Sciences Investors, LLC 664.0K 19.5%
GILEAD SCIENCES, INC. 650.4K 19.1%
ORBIMED ADVISORS LLC 592.3K 17.4%
Frazier Life Sciences Management, L.P. 422.5K 12.4%
Stonepine Capital Management, LLC 226.0K 6.6%
VANGUARD CAPITAL MANAGEMENT LLC 178.5K 5.2%
Sio Capital Management, LLC 152.5K 4.5%
ADAGE CAPITAL PARTNERS GP, L.L.C. 111.5K 3.3%
Merck & Co., Inc. 106.0K 3.1%
RENAISSANCE TECHNOLOGIES LLC 64.2K 1.9%
MORGAN STANLEY 57.0K 1.7%
GEODE CAPITAL MANAGEMENT, LLC 39.1K 1.1%
CITADEL ADVISORS LLC 26.0K 0.8%
VANGUARD FIDUCIARY TRUST CO 22.6K 0.7%
BRIDGEWAY CAPITAL MANAGEMENT, LLC 17.5K 0.5%
TWO SIGMA INVESTMENTS, LP 14.5K 0.4%
Velan Capital Investment Management LP 14.3K 0.4%
GSA CAPITAL PARTNERS LLP 13.6K 0.4%
STATE STREET CORP 13.3K 0.4%
PRELUDE CAPITAL MANAGEMENT, LLC 11.6K 0.3%
BlackRock, Inc. 8.8K 0.3%
Steward Partners Investment Advisory, LLC 714 0.0%
BARCLAYS PLC 115 0.0%
Key Financial Inc 59 0.0%
JONES FINANCIAL COMPANIES LLLP 29 0.0%

Largest changes

Manager Action Previous Current Change
ORBIMED ADVISORS LLC New 0 592.3K +592.3K
Stonepine Capital Management, LLC Increased 64.2K 226.0K +161.8K
Caligan Partners LP Sold Out 112.1K 0 -112.1K
ADAGE CAPITAL PARTNERS GP, L.L.C. New 0 111.5K +111.5K
VANGUARD CAPITAL MANAGEMENT LLC Increased 123.7K 178.5K +54.9K
FMR LLC Sold Out 36.6K 0 -36.6K
CITADEL ADVISORS LLC New 0 26.0K +26.0K
BRIDGEWAY CAPITAL MANAGEMENT, LLC New 0 17.5K +17.5K
RENAISSANCE TECHNOLOGIES LLC Increased 49.6K 64.2K +14.6K
TWO SIGMA INVESTMENTS, LP New 0 14.5K +14.5K
Ghisallo Capital Management LLC Sold Out 13.8K 0 -13.8K
PRELUDE CAPITAL MANAGEMENT, LLC New 0 11.6K +11.6K
BlackRock, Inc. New 0 8.8K +8.8K
VANGUARD FIDUCIARY TRUST CO Reduced 28.5K 22.6K -5.9K
UBS Group AG Reduced 4.0K 14 -4.0K
GSA CAPITAL PARTNERS LLP Reduced 16.9K 13.6K -3.4K
GEODE CAPITAL MANAGEMENT, LLC Increased 37.2K 39.1K +1.9K
Steward Partners Investment Advisory, LLC New 0 714 +714
MORGAN STANLEY Reduced 57.5K 57.0K -539
JPMORGAN CHASE & CO Sold Out 240 0 -240
Vanguard Global Advisers, LLC Sold Out 210 0 -210
BARCLAYS PLC New 0 115 +115
ROYAL BANK OF CANADA Sold Out 91 0 -91
JONES FINANCIAL COMPANIES LLLP New 0 29 +29

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.