AMLX Amylyx Pharmaceuticals, Inc.

NASDAQ
$33.64

Amylyx Pharmaceuticals, Inc. (AMLX) Hedge Fund Activity

This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.

Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.

Hedge fund breadth
+31.25
21 buyers / 11 sellers
STRONG BUYING
Funds compared
33
funds with comparable AMLX positions
30 current holders · 20 prior-quarter holders
Net share change
-287.2K
+3.16M added, -3.45M cut
Position activity
13 new 8 increased 8 reduced 3 exited

Most significant moves

Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.

Fund Action Shares changed Change Est. value Portfolio wt. Score
Point72 Asset Management, L.P. Sold Out -106.5K -100.0% $1.9M 0.0% 61
Alyeska Investment Group, L.P. New +1.05M $18.9M 0.1% 60
OrbiMed Advisors Growth Healthcare New +183.4K $3.3M 0.1% 59
Affinity Asset Advisors Long/Short Growth New +99.0K $1.8M 0.1% 58
Squarepoint Ops LLC Quant Sold Out -114.9K -100.0% $2.1M 0.0% 56
Magnetar Capital Event Quant New +11.7K $210.5K 0.0% 54
D. E. Shaw & Co., Inc. Quant Increased +100.1K +134.8% $1.8M 0.0% 54
Verition Fund Management Event Long/Short Sold Out -13.3K -100.0% $238.2K 0.0% 54
Hudson Bay Capital Management Event New +50.0K $898.0K 0.0% 53
Lighthouse Investment Partners New +122.9K $2.2M 0.1% 53

Most significant buyers

By move score, not size.

  • Alyeska Investment Group, L.P. New · +1.05M
  • OrbiMed Advisors New · +183.4K
  • Affinity Asset Advisors New · +99.0K
  • Magnetar Capital New · +11.7K
  • D. E. Shaw & Co., Inc. Increased · +100.1K

Most significant sellers

By move score, not size.

  • Point72 Asset Management, L.P. Sold Out · -106.5K
  • Squarepoint Ops LLC Sold Out · -114.9K
  • Verition Fund Management Sold Out · -13.3K
  • CITADEL ADVISORS LLC Reduced · -232.8K
  • Logos Global Management Reduced · -350.0K

Hedge fund positions

Fund Tier Shares Previous Change Change % Portfolio wt. Action Score
Point72 Asset Management, L.P. 1 0 106.5K -106.5K -100.0% 0.0% Sold Out 61
Alyeska Investment Group, L.P. 2 1.1M 0 +1.05M 0.1% New 60
OrbiMed Advisors 2 183.4K 0 +183.4K 0.1% New 59
Affinity Asset Advisors 2 99.0K 0 +99.0K 0.1% New 58
Squarepoint Ops LLC 2 0 114.9K -114.9K -100.0% 0.0% Sold Out 56
Magnetar Capital 2 11.7K 0 +11.7K 0.0% New 54
D. E. Shaw & Co., Inc. 1 174.3K 74.2K +100.1K +134.8% 0.0% Increased 54
Verition Fund Management 2 0 13.3K -13.3K -100.0% 0.0% Sold Out 54
Hudson Bay Capital Management 3 50.0K 0 +50.0K 0.0% New 53
Lighthouse Investment Partners 3 122.9K 0 +122.9K 0.1% New 53
Trexquant Investment 3 349.4K 0 +349.4K 0.0% New 53
TWO SIGMA INVESTMENTS, LP 2 593.4K 161.9K +431.5K +266.4% 0.0% Increased 53
Jain Global 3 28.8K 0 +28.8K 0.0% New 52
Caption Management 3 174 0 +174 0.0% New 50
Brevan Howard Capital Management 3 11.6K 0 +11.6K 0.0% New 49
Graham Capital Management 3 12.4K 0 +12.4K 0.0% New 49
Boothbay Fund Management 4 36.1K 0 +36.1K 0.0% New 49
Aquatic Capital Management 4 39.4K 0 +39.4K 0.0% New 48
Nantahala Capital Management 3 973.4K 535.7K +437.7K +81.7% 0.6% Increased 47
Walleye Capital 3 186.6K 61.7K +124.9K +202.4% 0.0% Increased 47
CITADEL ADVISORS LLC 1 178.7K 411.5K -232.8K -56.6% 0.0% Reduced 43
Logos Global Management 2 350.0K 700.0K -350.0K -50.0% 0.3% Reduced 42
ADAR1 Capital Management 3 494.4K 1.0M -506.2K -50.6% 0.4% Reduced 41
Perceptive Advisors 1 8.3M 8.3M +50.0K +0.6% 2.3% Increased 41
ADAGE CAPITAL PARTNERS GP, L.L.C. 2 1.9M 3.6M -1.66M -46.6% 0.0% Reduced 41
Balyasny Asset Management L.P. 2 685.0K 1.1M -422.3K -38.1% 0.0% Reduced 38
Alpha Wave Global 1 155.4K 142.3K +13.1K +9.2% 0.0% Increased 33
AQR Capital Management 3 20.8K 29.1K -8.3K -28.4% 0.0% Reduced 27
Tudor Investment Corporation 2 35.4K 31.3K +4.1K +13.0% 0.0% Increased 26
Qube Research & Technologies Ltd 2 681.4K 702.2K -20.8K -3.0% 0.0% Reduced 25
Schonfeld Strategic Advisors 3 66.8K 77.8K -11.0K -14.1% 0.0% Reduced 23
Woodline Partners LP 2 846.4K 845.8K +587 +0.1% 0.0% Increased 23
Rock Springs Capital Management 3 499.8K 499.8K 0 +0.0% 0.4% Unchanged 19

Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.

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Hedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.