AXSM Axsome Therapeutics, Inc.

NASDAQ
$220.75

Axsome Therapeutics, Inc. (AXSM) Insider Activity

What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.

Insider signal In line Selling ran below AXSM's own trailing one-year pace, with 100% of sale value under a prearranged plan.
Cluster activity 0 buyers in the last 30 days 0 buyers in the last 90 days 2 sellers in the last 90 days
Insiders buying
0
0 transactions
Insiders selling
7
17 transactions
Purchases
$0
0 shares
Sales
$51.4M
223,602 shares
Net activity
-$51.4M
purchases less sales

How much of that selling was preplanned? 100% planned / 0% discretionary

10b5-1 plan sales $51.4M 17 transactions · 223,602 shares
Discretionary sales $0 0 transactions · 0 shares

Largest single sale: $12.0M.

Where they traded

Buy Sell Dot area is proportional to transaction value.

Last open-market purchase: September 8, 2025 — 1.0 years ago, by Coleman Mark .

Recent open-market activity

Date Insider Role Action Shares Price Value Held after
Jacobson Mark L. Chief Operating Officer Sell 10b5-1 10,000 $208.65 $2.1M None left
TABUTEAU HERRIOT Chief Executive Officer Sell 10b5-1 4,660 $213.95 $997.0K 7,229 −39.2% of holding
TABUTEAU HERRIOT Chief Executive Officer Sell 10b5-1 45,004 $212.01 $9.5M 7,229 −86.2% of holding
TABUTEAU HERRIOT Chief Executive Officer Sell 10b5-1 49,666 $240.25 $11.9M 7,229 −87.3% of holding
JEFFS ROGER Director Sell 10b5-1 286 $249.12 $71.2K 58,367 −0.5% of holding
Coleman Mark Director Sell 10b5-1 643 $249.00 $160.1K 30,389 −2.1% of holding
Mahony Susan Director Sell 10b5-1 300 $246.18 $73.9K 829 −26.6% of holding
JEFFS ROGER Director Sell 10b5-1 286 $246.18 $70.4K 58,653 −0.5% of holding
TABUTEAU HERRIOT Chief Executive Officer Sell 10b5-1 49,670 $241.01 $12.0M 7,229 −87.3% of holding
Pizzie Nick Chief Financial Officer Sell 10b5-1 33,000 $240.09 $7.9M 42,867 −43.5% of holding
Mahony Susan Director Sell 10b5-1 300 $237.21 $71.2K 1,129 −21% of holding
Coleman Mark Director Sell 10b5-1 5,537 $223.39 $1.2M 29,603 −15.8% of holding
Coleman Mark Director Sell 10b5-1 6,000 $230.30 $1.4M 35,140 −14.6% of holding
Coleman Mark Director Sell 10b5-1 6,000 $233.46 $1.4M 41,140 −12.7% of holding
Jacobson Mark L. Chief Operating Officer Sell 10b5-1 233 $228.18 $53.2K None left
Jacobson Mark L. Chief Operating Officer Sell 10b5-1 4,517 $227.94 $1.0M None left
Maizel Ari Chief Commercial Officer Sell 10b5-1 7,500 $182.42 $1.4M None left

Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.