DFTX Definium Therapeutics, Inc.

NASDAQ
$39.28

Definium Therapeutics, Inc. (DFTX) Hedge Fund Activity

This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.

Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.

Hedge fund breadth
+22.73
27 buyers / 17 sellers
BUYING
Funds compared
44
funds with comparable DFTX positions
38 current holders · 30 prior-quarter holders
Net share change
+3.49M
+6.25M added, -2.77M cut
Position activity
14 new 13 increased 11 reduced 6 exited

Most significant moves

Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.

Fund Action Shares changed Change Est. value Portfolio wt. Score
RA Capital Management Growth Healthcare New +1.50M — $70.6M 0.6% 70
Avoro Capital Advisors Healthcare Increased +2.19M +43.8% $103.0M 3.0% 64
Logos Global Management Growth Healthcare New +80.0K — $3.8M 0.2% 58
Point72 Asset Management, L.P. Increased +308.5K +175.8% $14.5M 0.0% 58
Ghisallo Capital Management Long/Short New +41.5K — $2.0M 0.1% 57
Rock Springs Capital Management Growth Healthcare New +143.2K — $6.7M 0.3% 57
Squarepoint Ops LLC Quant Sold Out -125.5K -100.0% $5.9M 0.0% 57
LMR Partners Event Quant New +150.2K — $7.1M 0.1% 55
Trexquant Investment Quant New +233.2K — $11.0M 0.1% 55
Caxton Associates Macro Sold Out -37.3K -100.0% $1.8M 0.0% 55

Most significant buyers

By move score, not size.

  • RA Capital Management New · +1.50M
  • Avoro Capital Advisors Increased · +2.19M
  • Logos Global Management New · +80.0K
  • Point72 Asset Management, L.P. Increased · +308.5K
  • Ghisallo Capital Management New · +41.5K

Most significant sellers

By move score, not size.

  • Squarepoint Ops LLC Sold Out · -125.5K
  • Caxton Associates Sold Out · -37.3K
  • Magnetar Capital Sold Out · -13.2K
  • ExodusPoint Capital Management Sold Out · -104.9K
  • Verition Fund Management Sold Out · -10.4K

Hedge fund positions

Fund Tier Shares Previous Change Change % Portfolio wt. Action Score
RA Capital Management 1 1.5M 0 +1.50M — 0.6% New 70
Avoro Capital Advisors 1 7.2M 5.0M +2.19M +43.8% 3.0% Increased 64
Logos Global Management 2 80.0K 0 +80.0K — 0.2% New 58
Point72 Asset Management, L.P. 1 484.0K 175.5K +308.5K +175.8% 0.0% Increased 58
Ghisallo Capital Management 2 41.5K 0 +41.5K — 0.1% New 57
Rock Springs Capital Management 3 143.2K 0 +143.2K — 0.3% New 57
Squarepoint Ops LLC 2 0 125.5K -125.5K -100.0% 0.0% Sold Out 57
LMR Partners 3 150.2K 0 +150.2K — 0.1% New 55
Trexquant Investment 3 233.2K 0 +233.2K — 0.1% New 55
Caxton Associates 3 0 37.3K -37.3K -100.0% 0.0% Sold Out 55
Magnetar Capital 2 0 13.2K -13.2K -100.0% 0.0% Sold Out 54
Gotham Asset Management, LLC 2 4.4K 0 +4.4K — 0.0% New 54
ExodusPoint Capital Management 3 0 104.9K -104.9K -100.0% 0.0% Sold Out 54
Verition Fund Management 2 0 10.4K -10.4K -100.0% 0.0% Sold Out 54
Capital Fund Management 3 10.1K 0 +10.1K — 0.0% New 53
Jain Global 3 5.0K 0 +5.0K — 0.0% New 52
Y-Intercept 4 54.5K 0 +54.5K — 0.1% New 50
Aquatic Capital Management 4 43.1K 0 +43.1K — 0.1% New 50
Boothbay Fund Management 4 0 14.1K -14.1K -100.0% 0.0% Sold Out 49
Winton Group 4 5.1K 0 +5.1K — 0.0% New 48
Centiva Capital 4 7.2K 0 +7.2K — 0.0% New 48
MILLENNIUM MANAGEMENT LLC 2 266.1K 846.9K -580.8K -68.6% 0.0% Reduced 47
Schonfeld Strategic Advisors 3 119.6K 10.4K +109.2K +1048.8% 0.0% Increased 47
AQR Capital Management 3 134.2K 57.1K +77.1K +135.0% 0.0% Increased 47
OrbiMed Advisors 2 365.4K 804.0K -438.6K -54.6% 0.3% Reduced 45
Quantbot Technologies 4 9.2K 0 +9.2K — 0.0% New 45
Deep Track Capital 1 2.8M 3.0M -250.0K -8.3% 1.9% Reduced 45
Cinctive Capital Management 3 28.6K 12.6K +16.0K +127.5% 0.1% Increased 44
Qube Research & Technologies Ltd 2 682.9K 426.1K +256.8K +60.3% 0.0% Increased 43
Integral Health Asset Management 2 550.0K 400.0K +150.0K +37.5% 1.1% Increased 42
RTW Investments 1 400.0K 300.0K +100.0K +33.3% 0.2% Increased 41
Balyasny Asset Management L.P. 2 897.7K 1.3M -376.6K -29.6% 0.1% Reduced 38
CITADEL ADVISORS LLC 1 1.7M 1.3M +355.1K +26.6% 0.1% Increased 38
Woodline Partners LP 2 1.0M 752.8K +250.8K +33.3% 0.1% Increased 36
Holocene Advisors, LP 2 796.6K 1.1M -295.4K -27.1% 0.1% Reduced 36
TWO SIGMA INVESTMENTS, LP 2 921.8K 1.2M -279.8K -23.3% 0.0% Reduced 36
Engineers Gate 4 10.2K 29.8K -19.5K -65.6% 0.0% Reduced 33
D. E. Shaw & Co., Inc. 1 315.4K 271.7K +43.7K +16.1% 0.0% Increased 33
Walleye Capital 3 20.6K 35.5K -14.8K -41.8% 0.0% Reduced 31
ADAGE CAPITAL PARTNERS GP, L.L.C. 2 1.0M 1.2M -150.0K -13.0% 0.1% Reduced 30
MARSHALL WACE, LLP 2 1.3M 1.2M +98.1K +8.2% 0.1% Increased 30
Caption Management 3 45.0K 33.8K +11.2K +33.3% 0.1% Increased 28
Brevan Howard Capital Management 3 156.8K 211.5K -54.7K -25.9% 0.1% Reduced 27
CenterBook Partners 4 41.3K 42.8K -1.6K -3.7% 0.1% Reduced 19

Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.

Sign in or subscribe

Hedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.