PRLD Prelude Therapeutics Incorporated
Prelude Therapeutics Incorporated (PRLD) Institutional Ownership
What the institutions did with PRLD last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| ORBIMED ADVISORS LLC | 13.7M | 27.7% |
| BAKER BROS. ADVISORS LP | 10.1M | 20.4% |
| RA CAPITAL MANAGEMENT, L.P. | 6.5M | 13.1% |
| Soleus Capital Management, L.P. | 3.4M | 6.8% |
| Kynam Capital Management, LP | 2.4M | 4.9% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.0M | 4.1% |
| BlackRock, Inc. | 1.8M | 3.6% |
| SPHERA FUNDS MANAGEMENT LTD. | 1.0M | 2.1% |
| TWO SIGMA INVESTMENTS, LP | 993.4K | 2.0% |
| ADAR1 Capital Management, LLC | 900.9K | 1.8% |
| MILLENNIUM MANAGEMENT LLC | 845.0K | 1.7% |
| GEODE CAPITAL MANAGEMENT, LLC | 841.9K | 1.7% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 766.1K | 1.5% |
| ACADIAN ASSET MANAGEMENT LLC | 611.4K | 1.2% |
| MORGAN STANLEY | 503.9K | 1.0% |
| STATE STREET CORP | 428.8K | 0.9% |
| UBS Group AG | 318.8K | 0.6% |
| VANGUARD FIDUCIARY TRUST CO | 284.9K | 0.6% |
| RENAISSANCE TECHNOLOGIES LLC | 281.2K | 0.6% |
| NORTHERN TRUST CORP | 240.6K | 0.5% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 193.9K | 0.4% |
| MARSHALL WACE, LLP | 190.7K | 0.4% |
| Connor, Clark & Lunn Investment Management Ltd. | 125.6K | 0.3% |
| GOLDMAN SACHS GROUP INC | 120.8K | 0.2% |
| Hillsdale Investment Management Inc. | 81.4K | 0.2% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | New | 0 | 6.5M | +6.5M |
| Soleus Capital Management, L.P. | New | 0 | 3.4M | +3.4M |
| ORBIMED ADVISORS LLC | Increased | 10.9M | 13.7M | +2.8M |
| BlackRock, Inc. | Increased | 321.9K | 1.8M | +1.5M |
| EcoR1 Capital, LLC | Sold Out | 947.0K | 0 | -947.0K |
| Kynam Capital Management, LP | Increased | 1.6M | 2.4M | +822.5K |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 1.2M | 2.0M | +779.0K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | 0 | 766.1K | +766.1K |
| ADAR1 Capital Management, LLC | Increased | 152.8K | 900.9K | +748.1K |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 302.5K | 841.9K | +539.4K |
| MILLENNIUM MANAGEMENT LLC | Increased | 382.7K | 845.0K | +462.3K |
| SPHERA FUNDS MANAGEMENT LTD. | Increased | 558.3K | 1.0M | +461.5K |
| STATE STREET CORP | Increased | 138.2K | 428.8K | +290.6K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold Out | 267.8K | 0 | -267.8K |
| UBS Group AG | Increased | 64.5K | 318.8K | +254.3K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | 0 | 193.9K | +193.9K |
| JANE STREET GROUP, LLC | Sold Out | 193.0K | 0 | -193.0K |
| NORTHERN TRUST CORP | Increased | 50.1K | 240.6K | +190.5K |
| MORGAN STANLEY | Increased | 322.2K | 503.9K | +181.7K |
| MARSHALL WACE, LLP | Reduced | 358.9K | 190.7K | -168.2K |
| VANGUARD FIDUCIARY TRUST CO | Increased | 157.4K | 284.9K | +127.5K |
| GOLDMAN SACHS GROUP INC | Reduced | 236.5K | 120.8K | -115.6K |
| CITADEL ADVISORS LLC | Reduced | 124.4K | 22.6K | -101.8K |
| ACADIAN ASSET MANAGEMENT LLC | Increased | 511.5K | 611.4K | +99.8K |
| Hillsdale Investment Management Inc. | New | 0 | 81.4K | +81.4K |
| TWO SIGMA INVESTMENTS, LP | Increased | 923.6K | 993.4K | +69.7K |
| Bank of New York Mellon Corp | New | 0 | 68.2K | +68.2K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | New | 0 | 67.6K | +67.6K |
| Squarepoint Ops LLC | New | 0 | 59.5K | +59.5K |
| HRT FINANCIAL LP | Sold Out | 58.7K | 0 | -58.7K |
| XTX Topco Ltd | Sold Out | 57.2K | 0 | -57.2K |
| Focus Partners Wealth | Sold Out | 50.0K | 0 | -50.0K |
| PANAGORA ASSET MANAGEMENT INC | New | 0 | 47.6K | +47.6K |
| Mariner, LLC | New | 0 | 45.3K | +45.3K |
| Nuveen, LLC | New | 0 | 37.0K | +37.0K |
| Invesco Ltd. | New | 0 | 34.7K | +34.7K |
| State of Wyoming | New | 0 | 32.9K | +32.9K |
| OMERS ADMINISTRATION Corp | Sold Out | 32.7K | 0 | -32.7K |
| BANK OF AMERICA CORP /DE/ | Reduced | 56.5K | 23.9K | -32.7K |
| DEUTSCHE BANK AG\ | New | 0 | 27.8K | +27.8K |
| WELLS FARGO & COMPANY/MN | New | 0 | 25.3K | +25.3K |
| PRICE T ROWE ASSOCIATES INC /MD/ | New | 0 | 22.8K | +22.8K |
| RHUMBLINE ADVISERS | New | 0 | 22.1K | +22.1K |
| Graham Capital Management, L.P. | Increased | 11.3K | 29.8K | +18.4K |
| PRUDENTIAL FINANCIAL INC | Sold Out | 17.4K | 0 | -17.4K |
| Connor, Clark & Lunn Investment Management Ltd. | Increased | 109.1K | 125.6K | +16.5K |
| Point72 Asset Management, L.P. | Sold Out | 16.3K | 0 | -16.3K |
| ExodusPoint Capital Management, LP | New | 0 | 15.5K | +15.5K |
| NEW YORK STATE COMMON RETIREMENT FUND | New | 0 | 14.2K | +14.2K |
| JPMORGAN CHASE & CO | Increased | 62 | 13.5K | +13.5K |
| MANGROVE PARTNERS IM, LLC | New | 0 | 13.4K | +13.4K |
| CITIGROUP INC | Increased | 5 | 13.0K | +13.0K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | New | 0 | 12.8K | +12.8K |
| GSA CAPITAL PARTNERS LLP | New | 0 | 12.7K | +12.7K |
| Diametric Capital, LP | Sold Out | 12.0K | 0 | -12.0K |
| NINE MASTS CAPITAL Ltd | Sold Out | 11.7K | 0 | -11.7K |
| Vanguard Global Advisers, LLC | Increased | 4.6K | 16.2K | +11.6K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Increased | 53.5K | 64.5K | +11.0K |
| Spark Investment Management LLC | New | 0 | 10.6K | +10.6K |
| ALLIANCEBERNSTEIN L.P. | New | 0 | 10.5K | +10.5K |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.