PRLD Prelude Therapeutics Incorporated

NASDAQ
$4.47

Prelude Therapeutics Incorporated (PRLD) Hedge Fund Activity

This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.

Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.

Hedge fund breadth
+37.50
11 buyers / 5 sellers
STRONG BUYING
Funds compared
17
funds with comparable PRLD positions
15 current holders · 12 prior-quarter holders
Net share change
+13.58M
+14.82M added, -1.24M cut
Position activity
5 new 6 increased 3 reduced 2 exited

Most significant moves

Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.

Fund Action Shares changed Change Est. value Portfolio wt. Score
RA Capital Management Growth Healthcare New +6.48M — $34.5M 0.3% 67
Soleus Capital Management Growth Healthcare New +3.38M — $18.0M 0.6% 64
Point72 Asset Management, L.P. Sold Out -16.3K -100.0% $87.0K 0.0% 59
EcoR1 Capital Growth Healthcare Sold Out -947.0K -100.0% $5.0M 0.0% 58
ADAGE CAPITAL PARTNERS GP, L.L.C. New +766.1K — $4.1M 0.0% 58
Squarepoint Ops LLC Quant New +59.5K — $317.3K 0.0% 54
MILLENNIUM MANAGEMENT LLC Increased +462.3K +120.8% $2.5M 0.0% 53
ExodusPoint Capital Management Long/Short Quant New +15.5K — $82.5K 0.0% 52
ADAR1 Capital Management Long/Short Growth Increased +748.1K +489.5% $4.0M 0.2% 50
CITADEL ADVISORS LLC Quant Reduced -101.8K -81.9% $542.7K 0.0% 47

Most significant buyers

By move score, not size.

  • RA Capital Management New · +6.48M
  • Soleus Capital Management New · +3.38M
  • ADAGE CAPITAL PARTNERS GP, L.L.C. New · +766.1K
  • Squarepoint Ops LLC New · +59.5K
  • MILLENNIUM MANAGEMENT LLC Increased · +462.3K

Most significant sellers

By move score, not size.

  • Point72 Asset Management, L.P. Sold Out · -16.3K
  • EcoR1 Capital Sold Out · -947.0K
  • CITADEL ADVISORS LLC Reduced · -101.8K
  • MARSHALL WACE, LLP Reduced · -168.2K
  • Qube Research & Technologies Ltd Reduced · -3.3K

Hedge fund positions

Fund Tier Shares Previous Change Change % Portfolio wt. Action Score
RA Capital Management 1 6.5M 0 +6.48M — 0.3% New 67
Soleus Capital Management 2 3.4M 0 +3.38M — 0.6% New 64
Point72 Asset Management, L.P. 1 0 16.3K -16.3K -100.0% 0.0% Sold Out 59
EcoR1 Capital 2 0 947.0K -947.0K -100.0% 0.0% Sold Out 58
ADAGE CAPITAL PARTNERS GP, L.L.C. 2 766.1K 0 +766.1K — 0.0% New 58
Squarepoint Ops LLC 2 59.5K 0 +59.5K — 0.0% New 54
MILLENNIUM MANAGEMENT LLC 2 845.0K 382.7K +462.3K +120.8% 0.0% Increased 53
ExodusPoint Capital Management 3 15.5K 0 +15.5K — 0.0% New 52
ADAR1 Capital Management 3 900.9K 152.8K +748.1K +489.5% 0.2% Increased 50
CITADEL ADVISORS LLC 1 22.6K 124.4K -101.8K -81.9% 0.0% Reduced 47
OrbiMed Advisors 2 13.7M 10.9M +2.82M +25.8% 1.4% Increased 43
Graham Capital Management 3 29.8K 11.3K +18.4K +162.5% 0.0% Increased 43
MARSHALL WACE, LLP 2 190.7K 358.9K -168.2K -46.9% 0.0% Reduced 37
Qube Research & Technologies Ltd 2 13.1K 16.4K -3.3K -20.1% 0.0% Reduced 29
RENAISSANCE TECHNOLOGIES LLC 1 281.2K 275.2K +6.0K +2.2% 0.0% Increased 28
TWO SIGMA INVESTMENTS, LP 2 993.4K 923.6K +69.7K +7.6% 0.0% Increased 28
Baker Bros. Advisors 1 10.1M 10.1M 0 +0.0% 0.3% Unchanged 26

Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.

Sign in or subscribe

Hedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.