PRME Prime Medicine, Inc.
Prime Medicine, Inc. (PRME) Institutional Ownership
What the institutions did with PRME last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| Alphabet Inc. | 16.6M | 15.5% |
| BlackRock, Inc. | 9.6M | 9.0% |
| ARK Investment Management LLC | 8.3M | 7.8% |
| STATE STREET CORP | 7.6M | 7.1% |
| T. Rowe Price Investment Management, Inc. | 5.2M | 4.9% |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.5M | 4.2% |
| Balyasny Asset Management L.P. | 4.0M | 3.7% |
| GOLDMAN SACHS GROUP INC | 3.4M | 3.2% |
| Casdin Capital, LLC | 3.2M | 3.0% |
| Woodline Partners LP | 3.0M | 2.8% |
| UBS Group AG | 2.8M | 2.6% |
| GEODE CAPITAL MANAGEMENT, LLC | 2.7M | 2.5% |
| Sumitomo Mitsui Trust Group, Inc. | 2.4M | 2.3% |
| Amova Asset Management Americas, Inc. | 2.4M | 2.3% |
| CITADEL ADVISORS LLC | 2.1M | 1.9% |
| ADAR1 Capital Management, LLC | 2.0M | 1.9% |
| FMR LLC | 1.8M | 1.7% |
| TWO SIGMA INVESTMENTS, LP | 1.5M | 1.4% |
| Redmile Group, LLC | 1.4M | 1.3% |
| FARALLON CAPITAL MANAGEMENT LLC | 1.2M | 1.2% |
| Jump Financial, LLC | 1.2M | 1.2% |
| BANK OF AMERICA CORP /DE/ | 981.3K | 0.9% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 961.8K | 0.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 927.5K | 0.9% |
| NORTHERN TRUST CORP | 912.6K | 0.9% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| GOLDMAN SACHS GROUP INC | Increased | 970.4K | 3.4M | +2.5M |
| ARK Investment Management LLC | Increased | 6.2M | 8.3M | +2.1M |
| CITADEL ADVISORS LLC | Increased | 336.4K | 2.1M | +1.7M |
| Jump Financial, LLC | New | 0 | 1.2M | +1.2M |
| STATE STREET CORP | Increased | 6.3M | 7.6M | +1.2M |
| BlackRock, Inc. | Increased | 8.5M | 9.6M | +1.1M |
| D. E. Shaw & Co., Inc. | Reduced | 1.4M | 648.9K | -744.7K |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | 741.0K | 117.4K | -623.6K |
| Amova Asset Management Americas, Inc. | Reduced | 2.9M | 2.4M | -533.8K |
| Point72 Asset Management, L.P. | New | 0 | 533.6K | +533.6K |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | 2.9M | 2.4M | -527.8K |
| HRT FINANCIAL LP | Reduced | 612.8K | 161.5K | -451.3K |
| AQR CAPITAL MANAGEMENT LLC | Reduced | 554.9K | 118.0K | -436.9K |
| MILLENNIUM MANAGEMENT LLC | New | 0 | 427.1K | +427.1K |
| BANK OF AMERICA CORP /DE/ | Increased | 577.0K | 981.3K | +404.3K |
| T. Rowe Price Investment Management, Inc. | Reduced | 5.5M | 5.2M | -244.6K |
| Alessandra Capital Management, LLC | Increased | 425.5K | 666.6K | +241.1K |
| Jain Global LLC | New | 0 | 215.2K | +215.2K |
| Bollard Group LLC | Reduced | 361.1K | 151.1K | -210.0K |
| JUPITER ASSET MANAGEMENT LTD | New | 0 | 209.5K | +209.5K |
| PEAK6 LLC | New | 0 | 208.1K | +208.1K |
| Redmile Group, LLC | Reduced | 1.6M | 1.4M | -201.2K |
| Balyasny Asset Management L.P. | Reduced | 4.1M | 4.0M | -154.3K |
| Elevate Capital Advisors, LLC | Sold Out | 151.1K | 0 | -151.1K |
| CITIGROUP INC | Increased | 47.2K | 195.7K | +148.4K |
| ExodusPoint Capital Management, LP | New | 0 | 118.5K | +118.5K |
| MILESTONE ASSET MANAGEMENT, LLC | New | 0 | 100.0K | +100.0K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Increased | 862.2K | 961.8K | +99.6K |
| UBS Group AG | Reduced | 2.9M | 2.8M | -93.7K |
| MARSHALL WACE, LLP | Increased | 142.0K | 216.8K | +74.9K |
| COMMONWEALTH EQUITY SERVICES, LLC | Increased | 16.4K | 87.3K | +70.9K |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | Increased | 86.5K | 157.0K | +70.6K |
| Rafferty Asset Management, LLC | Reduced | 215.6K | 145.3K | -70.3K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Reduced | 134.8K | 64.8K | -70.0K |
| MORGAN STANLEY | Increased | 639.5K | 709.0K | +69.5K |
| WELLS FARGO & COMPANY/MN | Reduced | 319.6K | 251.7K | -67.8K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | 715.8K | 648.5K | -67.4K |
| TUDOR INVESTMENT CORP ET AL | Sold Out | 61.5K | 0 | -61.5K |
| SG Americas Securities, LLC | New | 0 | 58.9K | +58.9K |
| XTX Topco Ltd | Increased | 157.3K | 215.7K | +58.4K |
| Concurrent Investment Advisors, LLC | Increased | 74.2K | 131.7K | +57.5K |
| IEQ CAPITAL, LLC | Reduced | 74.0K | 16.5K | -57.5K |
| Aquatic Capital Management LLC | Sold Out | 54.2K | 0 | -54.2K |
| Mariner, LLC | Reduced | 78.4K | 25.4K | -53.0K |
| Virtus Investment Advisers, LLC | Increased | 66.5K | 117.9K | +51.4K |
| Engineers Gate Manager LP | Reduced | 110.3K | 59.1K | -51.2K |
| VANGUARD CAPITAL MANAGEMENT LLC | Increased | 4.5M | 4.5M | +48.5K |
| TWO SIGMA INVESTMENTS, LP | Reduced | 1.6M | 1.5M | -48.3K |
| VANGUARD FIDUCIARY TRUST CO | Increased | 717.0K | 764.6K | +47.6K |
| Invesco Ltd. | Increased | 96.9K | 140.3K | +43.4K |
| DEUTSCHE BANK AG\ | Reduced | 157.4K | 114.5K | -43.0K |
| VARCOV Co. | Sold Out | 42.0K | 0 | -42.0K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | Increased | 122.5K | 162.3K | +39.9K |
| AXQ CAPITAL, LP | Sold Out | 36.7K | 0 | -36.7K |
| JPMORGAN CHASE & CO | Reduced | 844.2K | 810.1K | -34.1K |
| BNP PARIBAS FINANCIAL MARKETS | Increased | 34.4K | 66.1K | +31.7K |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | 2.7M | 2.7M | -31.3K |
| TRANSCEND CAPITAL ADVISORS, LLC | Sold Out | 30.1K | 0 | -30.1K |
| Swiss National Bank | Increased | 178.6K | 208.3K | +29.7K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Increased | 52.6K | 82.3K | +29.7K |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.