PRME Prime Medicine, Inc.
Prime Medicine, Inc. (PRME) Institutional Ownership
What the institutions did with PRME last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended September 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| Alphabet Inc. | 16.6M | 74.9% |
| Sumitomo Mitsui Trust Group, Inc. | 2.9M | 13.2% |
| Alessandra Capital Management, LLC | 800.8K | 3.6% |
| Bank of New York Mellon Corp | 243.9K | 1.1% |
| BARCLAYS PLC | 209.2K | 0.9% |
| CITIGROUP INC | 167.3K | 0.8% |
| Green Alpha Advisors, LLC | 164.9K | 0.7% |
| COMMONWEALTH EQUITY SERVICES, LLC | 141.2K | 0.6% |
| Concurrent Investment Advisors, LLC | 137.2K | 0.6% |
| Pekin Hardy Strauss, Inc. | 114.5K | 0.5% |
| MILESTONE ASSET MANAGEMENT, LLC | 99.5K | 0.4% |
| OPPENHEIMER & CO INC | 79.9K | 0.4% |
| PROFUND ADVISORS LLC | 55.1K | 0.2% |
| Creative Planning | 34.7K | 0.2% |
| State of New Jersey Common Pension Fund D | 33.6K | 0.2% |
| China Universal Asset Management Co., Ltd. | 33.1K | 0.1% |
| Crestwood Advisors Group, LLC | 32.0K | 0.1% |
| ARIZONA STATE RETIREMENT SYSTEM | 29.3K | 0.1% |
| BLUE BELL PRIVATE WEALTH MANAGEMENT, LLC | 25.8K | 0.1% |
| Abacus Planning Group, Inc. | 25.2K | 0.1% |
| SHELTON WEALTH MANAGEMENT, LLC | 19.1K | 0.1% |
| ProShare Advisors LLC | 18.1K | 0.1% |
| Clearstead Advisors, LLC | 16.1K | 0.1% |
| LEVIN CAPITAL STRATEGIES, L.P. | 15.0K | 0.1% |
| DIMENSIONAL FUND ADVISORS LP | 13.4K | 0.1% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| Sumitomo Mitsui Trust Group, Inc. | Increased | 2.4M | 2.9M | +498.6K |
| DIMENSIONAL FUND ADVISORS LP | Reduced | 304.7K | 13.4K | -291.3K |
| Alessandra Capital Management, LLC | Increased | 666.6K | 800.8K | +134.2K |
| BARCLAYS PLC | Increased | 88.1K | 209.2K | +121.2K |
| Pekin Hardy Strauss, Inc. | New | 0 | 114.5K | +114.5K |
| COMMONWEALTH EQUITY SERVICES, LLC | Increased | 87.3K | 141.2K | +53.9K |
| OPPENHEIMER & CO INC | Increased | 29.7K | 79.9K | +50.3K |
| IvyRock Asset Management (HK) Ltd | Sold Out | 41.8K | 0 | -41.8K |
| CITIGROUP INC | Reduced | 195.7K | 167.3K | -28.3K |
| Cambridge Investment Research Advisors, Inc. | Reduced | 32.9K | 11.4K | -21.4K |
| Green Alpha Advisors, LLC | Reduced | 185.0K | 164.9K | -20.2K |
| PROFUND ADVISORS LLC | Reduced | 72.6K | 55.1K | -17.6K |
| Clearstead Advisors, LLC | Increased | 9 | 16.1K | +16.1K |
| Creative Planning | Increased | 21.3K | 34.7K | +13.4K |
| Prime Capital Investment Advisors, LLC | Sold Out | 12.9K | 0 | -12.9K |
| Veratis Advisors, Inc. | New | 0 | 10.8K | +10.8K |
| HB Wealth Management, LLC | New | 0 | 10.5K | +10.5K |
| PRINCIPAL FINANCIAL GROUP INC | New | 0 | 10.3K | +10.3K |
| Concurrent Investment Advisors, LLC | Increased | 131.7K | 137.2K | +5.5K |
| China Universal Asset Management Co., Ltd. | Increased | 28.7K | 33.1K | +4.3K |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | Reduced | 15.1K | 11.5K | -3.6K |
| THOMPSON DAVIS & CO., INC. | Reduced | 14.6K | 11.1K | -3.5K |
| Bank of New York Mellon Corp | Reduced | 246.3K | 243.9K | -2.4K |
| Sterling Capital Management LLC | Increased | 536 | 2.9K | +2.4K |
| Caitong International Asset Management Co., Ltd | Sold Out | 1.6K | 0 | -1.6K |
| Mirae Asset Global Investments Co., Ltd. | Increased | 8.1K | 9.3K | +1.2K |
| ARIZONA STATE RETIREMENT SYSTEM | Increased | 28.6K | 29.3K | +617 |
| Ascentis Independent Advisors | New | 0 | 600 | +600 |
| MILESTONE ASSET MANAGEMENT, LLC | Reduced | 100.0K | 99.5K | -583 |
| SBI Securities Co., Ltd. | Increased | 580 | 1.0K | +457 |
| EverSource Wealth Advisors, LLC | Reduced | 1.4K | 983 | -393 |
| GF FUND MANAGEMENT CO. LTD. | Increased | 3.8K | 4.2K | +340 |
| PNC FINANCIAL SERVICES GROUP, INC. | Sold Out | 319 | 0 | -319 |
| SIGNATUREFD, LLC | Increased | 5.0K | 5.3K | +300 |
| US BANCORP \DE\ | New | 0 | 230 | +230 |
| GAMMA Investing LLC | Increased | 586 | 761 | +175 |
| NISA INVESTMENT ADVISORS, LLC | Increased | 4.5K | 4.7K | +163 |
| Parkside Financial Bank & Trust | Increased | 285 | 425 | +140 |
| ProShare Advisors LLC | Reduced | 18.2K | 18.1K | -139 |
| EASTERN BANK | Sold Out | 134 | 0 | -134 |
| Root Financial Partners, LLC | New | 0 | 100 | +100 |
| TRUST CO OF VERMONT | New | 0 | 75 | +75 |
| Farther Finance Advisors, LLC | Sold Out | 55 | 0 | -55 |
| NATIXIS | Sold Out | 45 | 0 | -45 |
| Covestor Ltd | Reduced | 105 | 63 | -42 |
| Essential Partners LLC | Sold Out | 27 | 0 | -27 |
| Crestwood Advisors Group, LLC | Reduced | 32.0K | 32.0K | -17 |
| Fortitude Family Office, LLC | Reduced | 308 | 296 | -12 |
| Wealth Enhancement Trust Services, Inc. | Sold Out | 3 | 0 | -3 |
| IFP Advisors, Inc | Reduced | 23 | 20 | -3 |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.