PRME Prime Medicine, Inc.

NASDAQ
$3.64

Prime Medicine, Inc. (PRME) Institutional Ownership

What the institutions did with PRME last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
209
filed a 13F this quarter
Managers holding
186
-1 on the quarter
Buyers
86
22 opened new
Sellers
90
23 sold out entirely
Buyer share
48.9%
of managers who traded it
Breadth
-2.3
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
Alphabet Inc. 16.6M 15.5%
BlackRock, Inc. 9.6M 9.0%
ARK Investment Management LLC 8.3M 7.8%
STATE STREET CORP 7.6M 7.1%
T. Rowe Price Investment Management, Inc. 5.2M 4.9%
VANGUARD CAPITAL MANAGEMENT LLC 4.5M 4.2%
Balyasny Asset Management L.P. 4.0M 3.7%
GOLDMAN SACHS GROUP INC 3.4M 3.2%
Casdin Capital, LLC 3.2M 3.0%
Woodline Partners LP 3.0M 2.8%
UBS Group AG 2.8M 2.6%
GEODE CAPITAL MANAGEMENT, LLC 2.7M 2.5%
Sumitomo Mitsui Trust Group, Inc. 2.4M 2.3%
Amova Asset Management Americas, Inc. 2.4M 2.3%
CITADEL ADVISORS LLC 2.1M 1.9%
ADAR1 Capital Management, LLC 2.0M 1.9%
FMR LLC 1.8M 1.7%
TWO SIGMA INVESTMENTS, LP 1.5M 1.4%
Redmile Group, LLC 1.4M 1.3%
FARALLON CAPITAL MANAGEMENT LLC 1.2M 1.2%
Jump Financial, LLC 1.2M 1.2%
BANK OF AMERICA CORP /DE/ 981.3K 0.9%
VANGUARD PORTFOLIO MANAGEMENT LLC 961.8K 0.9%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 927.5K 0.9%
NORTHERN TRUST CORP 912.6K 0.9%

Largest changes

Manager Action Previous Current Change
GOLDMAN SACHS GROUP INC Increased 970.4K 3.4M +2.5M
ARK Investment Management LLC Increased 6.2M 8.3M +2.1M
CITADEL ADVISORS LLC Increased 336.4K 2.1M +1.7M
Jump Financial, LLC New 0 1.2M +1.2M
STATE STREET CORP Increased 6.3M 7.6M +1.2M
BlackRock, Inc. Increased 8.5M 9.6M +1.1M
D. E. Shaw & Co., Inc. Reduced 1.4M 648.9K -744.7K
RENAISSANCE TECHNOLOGIES LLC Reduced 741.0K 117.4K -623.6K
Amova Asset Management Americas, Inc. Reduced 2.9M 2.4M -533.8K
Point72 Asset Management, L.P. New 0 533.6K +533.6K
Sumitomo Mitsui Trust Group, Inc. Reduced 2.9M 2.4M -527.8K
HRT FINANCIAL LP Reduced 612.8K 161.5K -451.3K
AQR CAPITAL MANAGEMENT LLC Reduced 554.9K 118.0K -436.9K
MILLENNIUM MANAGEMENT LLC New 0 427.1K +427.1K
BANK OF AMERICA CORP /DE/ Increased 577.0K 981.3K +404.3K
T. Rowe Price Investment Management, Inc. Reduced 5.5M 5.2M -244.6K
Alessandra Capital Management, LLC Increased 425.5K 666.6K +241.1K
Jain Global LLC New 0 215.2K +215.2K
Bollard Group LLC Reduced 361.1K 151.1K -210.0K
JUPITER ASSET MANAGEMENT LTD New 0 209.5K +209.5K
PEAK6 LLC New 0 208.1K +208.1K
Redmile Group, LLC Reduced 1.6M 1.4M -201.2K
Balyasny Asset Management L.P. Reduced 4.1M 4.0M -154.3K
Elevate Capital Advisors, LLC Sold Out 151.1K 0 -151.1K
CITIGROUP INC Increased 47.2K 195.7K +148.4K

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.