PRME Prime Medicine, Inc.

NASDAQ
$3.14

Prime Medicine, Inc. (PRME) Hedge Fund Activity

This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.

Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.

Hedge fund breadth
+9.09
12 buyers / 10 sellers
MIXED
Funds compared
24
funds with comparable PRME positions
22 current holders · 18 prior-quarter holders
Net share change
+969.2K
+3.15M added, -2.18M cut
Position activity
6 new 6 increased 8 reduced 2 exited

Most significant moves

Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.

Fund Action Shares changed Change Est. value Portfolio wt. Score
Point72 Asset Management, L.P. New +533.6K — $2.0M 0.0% 61
MILLENNIUM MANAGEMENT LLC New +427.1K — $1.6M 0.0% 59
CITADEL ADVISORS LLC Quant Increased +1.72M +510.8% $6.3M 0.0% 54
Tudor Investment Corporation Macro Sold Out -61.5K -100.0% $227.1K 0.0% 53
ExodusPoint Capital Management Long/Short Quant New +118.5K — $437.1K 0.0% 52
Jain Global Long/Short Quant New +215.2K — $794.2K 0.0% 52
Schonfeld Strategic Advisors Long/Short Quant New +20.2K — $74.5K 0.0% 51
RENAISSANCE TECHNOLOGIES LLC Quant Reduced -623.6K -84.2% $2.3M 0.0% 50
Brevan Howard Capital Management Macro New +12.9K — $47.6K 0.0% 49
Aquatic Capital Management Quant Sold Out -54.2K -100.0% $200.1K 0.0% 48

Most significant buyers

By move score, not size.

  • Point72 Asset Management, L.P. New · +533.6K
  • MILLENNIUM MANAGEMENT LLC New · +427.1K
  • CITADEL ADVISORS LLC Increased · +1.72M
  • ExodusPoint Capital Management New · +118.5K
  • Jain Global New · +215.2K

Most significant sellers

By move score, not size.

  • Tudor Investment Corporation Sold Out · -61.5K
  • RENAISSANCE TECHNOLOGIES LLC Reduced · -623.6K
  • Aquatic Capital Management Sold Out · -54.2K
  • D. E. Shaw & Co., Inc. Reduced · -744.7K
  • AQR Capital Management Reduced · -436.9K

Hedge fund positions

Fund Tier Shares Previous Change Change % Portfolio wt. Action Score
Point72 Asset Management, L.P. 1 533.6K 0 +533.6K — 0.0% New 61
MILLENNIUM MANAGEMENT LLC 2 427.1K 0 +427.1K — 0.0% New 59
CITADEL ADVISORS LLC 1 2.1M 336.4K +1.72M +510.8% 0.0% Increased 54
Tudor Investment Corporation 2 0 61.5K -61.5K -100.0% 0.0% Sold Out 53
ExodusPoint Capital Management 3 118.5K 0 +118.5K — 0.0% New 52
Jain Global 3 215.2K 0 +215.2K — 0.0% New 52
Schonfeld Strategic Advisors 3 20.2K 0 +20.2K — 0.0% New 51
RENAISSANCE TECHNOLOGIES LLC 1 117.4K 741.0K -623.6K -84.2% 0.0% Reduced 50
Brevan Howard Capital Management 3 12.9K 0 +12.9K — 0.0% New 49
Aquatic Capital Management 4 0 54.2K -54.2K -100.0% 0.0% Sold Out 48
D. E. Shaw & Co., Inc. 1 648.9K 1.4M -744.7K -53.4% 0.0% Reduced 42
AQR Capital Management 3 118.0K 554.9K -436.9K -78.7% 0.0% Reduced 41
MARSHALL WACE, LLP 2 216.8K 142.0K +74.9K +52.8% 0.0% Increased 38
Magnetar Capital 2 21.2K 15.8K +5.4K +34.1% 0.0% Increased 32
Engineers Gate 4 59.1K 110.3K -51.2K -46.4% 0.0% Reduced 28
Balyasny Asset Management L.P. 2 4.0M 4.1M -154.3K -3.7% 0.0% Reduced 27
TWO SIGMA INVESTMENTS, LP 2 1.5M 1.6M -48.3K -3.1% 0.0% Reduced 26
Squarepoint Ops LLC 2 88.0K 94.1K -6.0K -6.4% 0.0% Reduced 25
ADAR1 Capital Management 3 2.0M 2.0M +24.3K +1.2% 0.4% Increased 25
Quadrature Capital 3 43.7K 46.9K -3.2K -6.9% 0.0% Reduced 23
Woodline Partners LP 2 3.0M 3.0M +591 +0.0% 0.0% Increased 23
Graham Capital Management 3 18.5K 16.0K +2.5K +15.6% 0.0% Increased 22
Farallon Capital Management 1 1.2M 1.2M 0 +0.0% 0.0% Unchanged 24
Moore Capital Management 3 500.0K 500.0K 0 +0.0% 0.1% Unchanged 16

Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.

Sign in or subscribe

Hedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.