TSHA Taysha Gene Therapies, Inc.
Taysha Gene Therapies, Inc. (TSHA) Hedge Fund Activity
This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.
Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.
Most significant moves
Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.
| Fund | Action | Shares changed | Change | Est. value | Portfolio wt. | Score |
|---|---|---|---|---|---|---|
| Deerfield Management Growth Healthcare | Sold Out | -2.72M | -100.0% | $18.5M | 0.0% | 65 |
| Farallon Capital Management Event Value | New | +2.25M | — | $15.3M | 0.1% | 64 |
| OrbiMed Advisors Growth Healthcare | New | +2.00M | — | $13.6M | 0.3% | 62 |
| Point72 Asset Management, L.P. | Sold Out | -461.9K | -100.0% | $3.1M | 0.0% | 61 |
| RENAISSANCE TECHNOLOGIES LLC Quant | Sold Out | -413.2K | -100.0% | $2.8M | 0.0% | 60 |
| Holocene Advisors, LP | New | +510.0K | — | $3.5M | 0.0% | 58 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +553.0K | — | $3.8M | 0.0% | 58 |
| Ghisallo Capital Management Long/Short | New | +505.0K | — | $3.4M | 0.1% | 57 |
| Qube Research & Technologies Ltd Quant | New | +259.6K | — | $1.8M | 0.0% | 57 |
| Weiss Asset Management Event Quant | New | +19.1K | — | $130.4K | 0.0% | 54 |
Most significant buyers
By move score, not size.
- Farallon Capital Management
- OrbiMed Advisors
- Holocene Advisors, LP
- ADAGE CAPITAL PARTNERS GP, L.L.C.
- Ghisallo Capital Management
Most significant sellers
By move score, not size.
- Deerfield Management
- Point72 Asset Management, L.P.
- RENAISSANCE TECHNOLOGIES LLC
- Tudor Investment Corporation
- Hudson Bay Capital Management
Hedge fund positions
| Fund | Tier | Shares | Previous | Change | Change % | Portfolio wt. | Action | Score |
|---|---|---|---|---|---|---|---|---|
| Deerfield Management | 1 | 0 | 2.7M | -2.72M | -100.0% | 0.0% | Sold Out | 65 |
| Farallon Capital Management | 1 | 2.3M | 0 | +2.25M | — | 0.1% | New | 64 |
| OrbiMed Advisors | 2 | 2.0M | 0 | +2.00M | — | 0.3% | New | 62 |
| Point72 Asset Management, L.P. | 1 | 0 | 461.9K | -461.9K | -100.0% | 0.0% | Sold Out | 61 |
| RENAISSANCE TECHNOLOGIES LLC | 1 | 0 | 413.2K | -413.2K | -100.0% | 0.0% | Sold Out | 60 |
| Holocene Advisors, LP | 2 | 510.0K | 0 | +510.0K | — | 0.0% | New | 58 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2 | 553.0K | 0 | +553.0K | — | 0.0% | New | 58 |
| Ghisallo Capital Management | 2 | 505.0K | 0 | +505.0K | — | 0.1% | New | 57 |
| Qube Research & Technologies Ltd | 2 | 259.6K | 0 | +259.6K | — | 0.0% | New | 57 |
| Weiss Asset Management | 2 | 19.1K | 0 | +19.1K | — | 0.0% | New | 54 |
| CITADEL ADVISORS LLC | 1 | 1.5M | 411.1K | +1.12M | +273.4% | 0.0% | Increased | 54 |
| Tudor Investment Corporation | 2 | 0 | 143.6K | -143.6K | -100.0% | 0.0% | Sold Out | 53 |
| Hudson Bay Capital Management | 3 | 0 | 10.7K | -10.7K | -100.0% | 0.0% | Sold Out | 53 |
| Trexquant Investment | 3 | 379.6K | 0 | +379.6K | — | 0.0% | New | 53 |
| Balyasny Asset Management L.P. | 2 | 189.3K | 83.0K | +106.3K | +128.1% | 0.0% | Increased | 51 |
| Y-Intercept | 4 | 0 | 11.5K | -11.5K | -100.0% | 0.0% | Sold Out | 48 |
| Engineers Gate | 4 | 104.1K | 0 | +104.1K | — | 0.0% | New | 48 |
| Affinity Asset Advisors | 2 | 1.8M | 1.0M | +750.0K | +75.0% | 0.6% | Increased | 48 |
| Vestal Point Capital | 1 | 19.4M | 18.0M | +1.42M | +7.9% | 3.1% | Increased | 47 |
| Quantbot Technologies | 4 | 0 | 524 | -524 | -100.0% | 0.0% | Sold Out | 45 |
| TWO SIGMA INVESTMENTS, LP | 2 | 234.7K | 742.1K | -507.4K | -68.4% | 0.0% | Reduced | 45 |
| J. Goldman & Co. | 3 | 67.3K | 33.8K | +33.6K | +99.6% | 0.0% | Increased | 44 |
| Avoro Capital Advisors | 1 | 23.9M | 21.7M | +2.19M | +10.1% | 1.5% | Increased | 43 |
| Aquatic Capital Management | 4 | 108.2K | 39.9K | +68.4K | +171.5% | 0.0% | Increased | 42 |
| MILLENNIUM MANAGEMENT LLC | 2 | 2.1M | 3.3M | -1.15M | -35.2% | 0.0% | Reduced | 37 |
| Squarepoint Ops LLC | 2 | 569.3K | 410.3K | +159.0K | +38.8% | 0.0% | Increased | 35 |
| RTW Investments | 1 | 13.6M | 13.7M | -120.0K | -0.9% | 0.8% | Reduced | 34 |
| ADAR1 Capital Management | 3 | 3.0M | 3.0M | +61.0K | +2.0% | 1.0% | Increased | 28 |
| D. E. Shaw & Co., Inc. | 1 | 4.4M | 4.4M | -28.6K | -0.6% | 0.0% | Reduced | 27 |
| AQR Capital Management | 3 | 128.8K | 177.3K | -48.5K | -27.4% | 0.0% | Reduced | 26 |
| Quadrature Capital | 3 | 25.8K | 23.5K | +2.3K | +9.6% | 0.0% | Increased | 24 |
| Moore Capital Management | 3 | 358.4K | 328.8K | +29.5K | +9.0% | 0.1% | Increased | 24 |
| Magnetar Capital | 2 | 11.5K | 11.4K | +66 | +0.6% | 0.0% | Increased | 24 |
| RA Capital Management | 1 | 23.6M | 23.6M | 0 | +0.0% | 1.4% | Unchanged | 32 |
| Palo Alto Investors | 2 | 1.4M | 1.4M | 0 | +0.0% | 1.4% | Unchanged | 26 |
| Baker Bros. Advisors | 1 | 4.0M | 4.0M | 0 | +0.0% | 0.1% | Unchanged | 26 |
| Woodline Partners LP | 2 | 513.8K | 513.8K | 0 | +0.0% | 0.0% | Unchanged | 18 |
Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeHedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.