TYRA Tyra Biosciences, Inc.
Tyra Biosciences, Inc. (TYRA) Hedge Fund Activity
This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.
Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.
Most significant moves
Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.
| Fund | Action | Shares changed | Change | Est. value | Portfolio wt. | Score |
|---|---|---|---|---|---|---|
| Farallon Capital Management Event Value | Sold Out | -3.58M | -100.0% | $114.4M | 0.0% | 72 |
| Logos Global Management Growth Healthcare | Sold Out | -850.0K | -100.0% | $27.1M | 0.0% | 68 |
| Caligan Partners Activist Event | Reduced | -470.0K | -36.8% | $15.0M | 1.2% | 62 |
| Point72 Asset Management, L.P. | Sold Out | -38.9K | -100.0% | $1.2M | 0.0% | 61 |
| Balyasny Asset Management L.P. | Sold Out | -351.5K | -100.0% | $11.2M | 0.0% | 61 |
| Vestal Point Capital Growth Healthcare | Sold Out | -54.0K | -100.0% | $1.7M | 0.0% | 61 |
| OrbiMed Advisors Growth Healthcare | New | +102.0K | — | $3.3M | 0.1% | 59 |
| D. E. Shaw & Co., Inc. Quant | New | +20.2K | — | $644.8K | 0.0% | 58 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +162.0K | — | $5.2M | 0.0% | 58 |
| Qube Research & Technologies Ltd Quant | New | +266.9K | — | $8.5M | 0.0% | 57 |
Most significant buyers
By move score, not size.
- OrbiMed Advisors
- D. E. Shaw & Co., Inc.
- ADAGE CAPITAL PARTNERS GP, L.L.C.
- Qube Research & Technologies Ltd
- Deerfield Management
Most significant sellers
By move score, not size.
- Farallon Capital Management
- Logos Global Management
- Caligan Partners
- Point72 Asset Management, L.P.
- Balyasny Asset Management L.P.
Hedge fund positions
| Fund | Tier | Shares | Previous | Change | Change % | Portfolio wt. | Action | Score |
|---|---|---|---|---|---|---|---|---|
| Farallon Capital Management | 1 | 0 | 3.6M | -3.58M | -100.0% | 0.0% | Sold Out | 72 |
| Logos Global Management | 2 | 0 | 850.0K | -850.0K | -100.0% | 0.0% | Sold Out | 68 |
| Caligan Partners | 2 | 807.0K | 1.3M | -470.0K | -36.8% | 1.2% | Reduced | 62 |
| Point72 Asset Management, L.P. | 1 | 0 | 38.9K | -38.9K | -100.0% | 0.0% | Sold Out | 61 |
| Balyasny Asset Management L.P. | 2 | 0 | 351.5K | -351.5K | -100.0% | 0.0% | Sold Out | 61 |
| Vestal Point Capital | 1 | 0 | 54.0K | -54.0K | -100.0% | 0.0% | Sold Out | 61 |
| OrbiMed Advisors | 2 | 102.0K | 0 | +102.0K | — | 0.1% | New | 59 |
| D. E. Shaw & Co., Inc. | 1 | 20.2K | 0 | +20.2K | — | 0.0% | New | 58 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2 | 162.0K | 0 | +162.0K | — | 0.0% | New | 58 |
| Qube Research & Technologies Ltd | 2 | 266.9K | 0 | +266.9K | — | 0.0% | New | 57 |
| Deerfield Management | 1 | 1.0M | 549.0K | +468.0K | +85.2% | 0.4% | Increased | 57 |
| Soleus Capital Management | 2 | 0 | 10.0K | -10.0K | -100.0% | 0.0% | Sold Out | 57 |
| TWO SIGMA INVESTMENTS, LP | 2 | 449.8K | 101.6K | +348.2K | +342.6% | 0.0% | Increased | 55 |
| MARSHALL WACE, LLP | 2 | 583.1K | 197.7K | +385.4K | +194.9% | 0.0% | Increased | 54 |
| CITADEL ADVISORS LLC | 1 | 278.3K | 15.4K | +262.9K | +1707.7% | 0.0% | Increased | 54 |
| Tudor Investment Corporation | 2 | 0 | 16.3K | -16.3K | -100.0% | 0.0% | Sold Out | 53 |
| Schonfeld Strategic Advisors | 3 | 0 | 79.6K | -79.6K | -100.0% | 0.0% | Sold Out | 53 |
| Capstone Investment Advisors | 3 | 10.1K | 0 | +10.1K | — | 0.0% | New | 53 |
| LMR Partners | 3 | 21.2K | 0 | +21.2K | — | 0.0% | New | 53 |
| Quadrature Capital | 3 | 0 | 18.2K | -18.2K | -100.0% | 0.0% | Sold Out | 53 |
| Jain Global | 3 | 8.6K | 0 | +8.6K | — | 0.0% | New | 52 |
| Brevan Howard Capital Management | 3 | 0 | 38.6K | -38.6K | -100.0% | 0.0% | Sold Out | 51 |
| Squarepoint Ops LLC | 2 | 63.8K | 20.5K | +43.3K | +211.3% | 0.0% | Increased | 51 |
| Engineers Gate | 4 | 32.0K | 0 | +32.0K | — | 0.0% | New | 50 |
| Walleye Capital | 3 | 347.9K | 18.7K | +329.2K | +1758.9% | 0.1% | Increased | 50 |
| Biotechnology Value Fund | 1 | 1.5M | 2.0M | -500.0K | -25.3% | 1.2% | Reduced | 49 |
| Graham Capital Management | 3 | 0 | 5.8K | -5.8K | -100.0% | 0.0% | Sold Out | 49 |
| Winton Group | 4 | 16.8K | 0 | +16.8K | — | 0.0% | New | 48 |
| ExodusPoint Capital Management | 3 | 41.0K | 14.1K | +27.0K | +191.7% | 0.0% | Increased | 46 |
| Quantbot Technologies | 4 | 0 | 243 | -243 | -100.0% | 0.0% | Sold Out | 45 |
| Cinctive Capital Management | 3 | 10.2K | 78.0K | -67.8K | -86.9% | 0.0% | Reduced | 43 |
| Paradigm BioCapital Advisors | 1 | 1.8M | 2.1M | -226.4K | -11.0% | 1.1% | Reduced | 41 |
| Affinity Asset Advisors | 2 | 200.0K | 257.5K | -57.5K | -22.3% | 0.3% | Reduced | 35 |
| MILLENNIUM MANAGEMENT LLC | 2 | 177.7K | 221.6K | -43.9K | -19.8% | 0.0% | Reduced | 33 |
| Boothbay Fund Management | 4 | 173.6K | 273.3K | -99.7K | -36.5% | 0.1% | Reduced | 30 |
| Woodline Partners LP | 2 | 320.0K | 301.0K | +19.0K | +6.3% | 0.0% | Increased | 25 |
| Trexquant Investment | 3 | 132.7K | 147.3K | -14.6K | -9.9% | 0.0% | Reduced | 22 |
| AQR Capital Management | 3 | 29.9K | 29.4K | +430 | +1.5% | 0.0% | Increased | 20 |
| RA Capital Management | 1 | 12.2M | 12.2M | 0 | +0.0% | 3.4% | Unchanged | 50 |
| Baker Bros. Advisors | 1 | 10.6K | 10.6K | 0 | +0.0% | 0.0% | Unchanged | 25 |
Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeHedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.