UPB Upstream Bio, Inc.

NASDAQ
$5.36

Upstream Bio, Inc. (UPB) Insider Activity

What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.

Insider signal In line Selling ran in line with UPB's own trailing one-year pace, with 0% of sale value under a prearranged plan.
Cluster activity 0 buyers in the last 30 days 0 buyers in the last 90 days 5 sellers in the last 90 days
Insiders buying
0
0 transactions
Insiders selling
5
10 transactions
Purchases
$0
0 shares
Sales
$58.2K
10,048 shares
Net activity
-$58.2K
purchases less sales

How much of that selling was preplanned? 0% planned / 100% discretionary

10b5-1 plan sales $0 0 transactions · 0 shares
Discretionary sales $58.2K 10 transactions · 10,048 shares

Largest single sale: $12.8K.

Where they traded

Buy Sell Dot area is proportional to transaction value.

No open-market insider purchase on record.

Recent open-market activity

Date Insider Role Action Shares Price Value Held after
Sutherland Everett Rand Chief Executive Officer Sell 2,095 $5.49 $11.5K 68,717 −3% of holding
Deykin Aaron Chief Medical Officer Sell 895 $5.49 $4.9K 32,302 −2.7% of holding
GRAY MICHAEL CFO and COO Sell 853 $5.49 $4.7K 27,942 −3% of holding
Houghton Adam Chief Business Officer Sell 700 $5.49 $3.8K 22,901 −3% of holding
Ambrose Allison General Counsel Sell 485 $5.49 $2.7K 15,563 −3% of holding
Sutherland Everett Rand Chief Executive Officer Sell 2,095 $6.10 $12.8K 70,812 −2.9% of holding
Deykin Aaron Chief Medical Officer Sell 895 $6.10 $5.5K 33,197 −2.6% of holding
GRAY MICHAEL CFO and COO Sell 853 $6.10 $5.2K 28,795 −2.9% of holding
Houghton Adam Chief Business Officer Sell 700 $6.10 $4.3K 23,601 −2.9% of holding
Ambrose Allison General Counsel Sell 477 $6.10 $2.9K 16,048 −2.9% of holding

Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.