VRTX Vertex Pharmaceuticals Incorporated

NASDAQ
$513.26

Vertex Pharmaceuticals Incorporated (VRTX) Insider Activity

What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.

Insider signal In line Selling ran in line with VRTX's own trailing one-year pace, with 100% of sale value under a prearranged plan.
Cluster activity 0 buyers in the last 30 days 0 buyers in the last 90 days 4 sellers in the last 90 days
Insiders buying
0
0 transactions
Insiders selling
13
94 transactions
Purchases
$0
0 shares
Sales
$158.4M
343,058 shares
Net activity
-$158.4M
purchases less sales

How much of that selling was preplanned? 100% planned / 0% discretionary

10b5-1 plan sales $158.4M 94 transactions · 343,058 shares
Discretionary sales $0 0 transactions · 0 shares

Largest single sale: $14.2M.

Where they traded

Buy Sell Dot area is proportional to transaction value.

No open-market insider purchase on record.

Recent open-market activity

Date Insider Role Action Shares Price Value Held after
McKechnie Duncan EVP, Chief Commercial Officer Sell 10b5-1 1,541 $519.00 $799.8K 11,001 −12.3% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 1,500 $524.99 $787.5K 45,321 −3.2% of holding
Liu Joy EVP and Chief Legal Officer Sell 10b5-1 828 $502.71 $416.2K 19,131 −4.1% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 596 $482.50 $287.6K 15,337 −3.7% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 1,020 $462.17 $471.4K 15,933 −6% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 4,062 $450.00 $1.8M 16,953 −19.3% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 1,745 $450.00 $785.3K 21,015 −7.7% of holding
Liu Joy EVP and Chief Legal Officer Sell 10b5-1 828 $439.91 $364.2K 19,959 −4% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 1,974 $450.00 $888.3K 22,760 −8% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 1,354 $453.45 $614.0K 24,734 −5.2% of holding
Bunnage Mark E. EVP, Chief Scientific Officer Sell 10b5-1 33 $453.45 $15.0K 7,284 −0.5% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 6,988 $450.00 $3.1M 26,088 −21.1% of holding
Bhatia Sangeeta N. Director Sell 10b5-1 318 $423.73 $134.7K 4,924 −6.1% of holding
Liu Joy EVP and Chief Legal Officer Sell 10b5-1 1,104 $425.02 $469.2K 20,729 −5.1% of holding
Liu Joy EVP and Chief Legal Officer Sell 10b5-1 978 $449.17 $439.3K 21,833 −4.3% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 2,329 $450.95 $1.1M 33,076 −6.6% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 2,329 $481.79 $1.1M 35,405 −6.2% of holding
McKechnie Duncan EVP, Chief Commercial Officer Sell 10b5-1 2,633 $498.42 $1.3M 12,489 −17.4% of holding
McKechnie Duncan EVP, Chief Commercial Officer Sell 10b5-1 2,437 $475.30 $1.2M 15,122 −13.9% of holding
Liu Joy EVP and Chief Legal Officer Sell 10b5-1 892 $495.96 $442.4K 22,811 −3.8% of holding
Kewalramani Reshma 13 fills CEO & President Sell 10b5-1 40,000 $493.47 $19.7M 137,878 −22.5% of holding
Bozic Carmen EVP and CMO Sell 10b5-1 2,329 $480.31 $1.1M 37,734 −5.8% of holding
Ambrose Kristen SVP & Chief Accounting Officer Sell 10b5-1 357 $483.36 $172.6K 6,624 −5.1% of holding
McKechnie Duncan 2 fills EVP, Chief Commercial Officer Sell 10b5-1 4,910 $487.65 $2.4M 19,969 −19.7% of holding
Sachdev Amit EVP Chief Patient & Ext Af Off Sell 10b5-1 1,846 $486.35 $897.8K 55,570 −3.2% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 945 $486.35 $459.6K 13,659 −6.5% of holding
Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 10b5-1 668 $486.35 $324.9K 18,432 −3.5% of holding
Bunnage Mark E. EVP, Chief Scientific Officer Sell 10b5-1 620 $486.35 $301.5K 7,284 −7.8% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 260 $486.35 $126.5K 46,763 −0.6% of holding
Ambrose Kristen SVP & Chief Accounting Officer Sell 10b5-1 223 $486.35 $108.5K 6,981 −3.1% of holding
Sachdev Amit 8 fills EVP Chief Patient & Ext Af Off Sell 10b5-1 58,613 $468.83 $27.5M 116,627 −33.4% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 1,244 $473.68 $589.3K 15,748 −7.3% of holding
Bunnage Mark E. EVP, Chief Scientific Officer Sell 10b5-1 1,182 $473.68 $559.9K 8,486 −12.2% of holding
Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 10b5-1 817 $473.68 $387.0K 20,727 −3.8% of holding
Ambrose Kristen SVP & Chief Accounting Officer Sell 10b5-1 638 $473.68 $302.2K 7,750 −7.6% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 368 $473.68 $174.3K 48,650 −0.8% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 2,476 $489.46 $1.2M 16,992 −12.7% of holding
Bunnage Mark E. EVP, Chief Scientific Officer Sell 10b5-1 2,437 $489.46 $1.2M 9,668 −20.1% of holding
Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 10b5-1 2,031 $489.46 $994.1K 21,544 −8.6% of holding
Ambrose Kristen SVP & Chief Accounting Officer Sell 10b5-1 1,557 $489.46 $762.1K 8,388 −15.7% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 609 $489.46 $298.1K 49,018 −1.2% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 1,500 $499.99 $750.0K 46,132 −3.1% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 988 $499.00 $493.0K 16,838 −5.5% of holding
Bhatia Sangeeta N. Director Sell 10b5-1 266 $500.00 $133.0K 4,299 −5.8% of holding
Bunnage Mark E. EVP, Chief Scientific Officer Sell 10b5-1 2,021 $460.43 $930.5K 12,914 −13.5% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 1,925 $460.43 $886.3K 20,819 −8.5% of holding
Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 10b5-1 1,751 $460.43 $806.2K 22,046 −7.4% of holding
Ambrose Kristen SVP & Chief Accounting Officer Sell 10b5-1 1,376 $460.43 $633.6K 10,127 −12% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 466 $460.43 $214.6K 51,436 −0.9% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 4,500 $474.99 $2.1M 42,293 −9.6% of holding
WAGNER CHARLES F JR EVP, CO & FO Sell 10b5-1 9,532 $461.00 $4.4M 37,725 −20.2% of holding
LEIDEN JEFFREY M 12 fills Executive Chairman Sell 10b5-1 63,781 $449.20 $28.7M 83,338 −43.4% of holding
WAGNER CHARLES F JR 2 fills EVP, CO & FO Sell 10b5-1 14,000 $456.00 $6.4M 44,725 −23.8% of holding
Tatsis Ourania EVP, Chief Reg. & Quality Off. Sell 10b5-1 4,500 $449.99 $2.0M 46,793 −8.8% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 347 $449.00 $155.8K 15,306 −2.2% of holding
Atkinson Edward Morrow III EVP, Chief Technical Ops. Off. Sell 10b5-1 2,500 $434.58 $1.1M 16,852 −12.9% of holding
LEIDEN JEFFREY M 3 fills Executive Chairman Sell 10b5-1 53,604 $440.72 $23.6M 45,396 −54.1% of holding
LEIDEN JEFFREY M 2 fills Executive Chairman Sell 10b5-1 19,688 $440.27 $8.7M 25,186 −43.9% of holding
Biller Jonathan EVP and Chief Legal Officer Sell 10b5-1 694 $404.21 $280.5K 15,653 −4.2% of holding

Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.