XENE Xenon Pharmaceuticals Inc.
Xenon Pharmaceuticals Inc. (XENE) Institutional Ownership
What the institutions did with XENE last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
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Each block is one manager, sized by shares held and colored by how much they moved the position last quarter. Green added, red cut, grey stood pat.
Largest holders
| Manager | Shares | % of reported |
|---|---|---|
| FMR LLC | 9.6M | 9.5% |
| BlackRock, Inc. | 7.5M | 7.4% |
| Avoro Capital Advisors LLC | 5.8M | 5.7% |
| Polar Capital Holdings Plc | 4.6M | 4.5% |
| Driehaus Capital Management LLC | 4.4M | 4.4% |
| Jupiter Topco LLC | 4.2M | 4.1% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.2M | 3.2% |
| JPMORGAN CHASE & CO | 2.6M | 2.6% |
| Capital International Investors | 2.4M | 2.3% |
| T. Rowe Price Investment Management, Inc. | 2.2M | 2.1% |
| STATE STREET CORP | 2.0M | 1.9% |
| TWO SIGMA INVESTMENTS, LP | 1.6M | 1.6% |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 1.6M | 1.6% |
| Affinity Asset Advisors, LLC | 1.6M | 1.6% |
| ALLIANCEBERNSTEIN L.P. | 1.6M | 1.5% |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1.5M | 1.5% |
| FRANKLIN RESOURCES INC | 1.4M | 1.4% |
| WELLINGTON MANAGEMENT GROUP LLP | 1.4M | 1.4% |
| CITADEL ADVISORS LLC | 1.4M | 1.4% |
| GEODE CAPITAL MANAGEMENT, LLC | 1.4M | 1.4% |
| Siren, L.L.C. | 1.3M | 1.3% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1.3M | 1.3% |
| Pictet Asset Management Holding SA | 1.2M | 1.2% |
| BRAIDWELL LP | 1.1M | 1.1% |
| Nuveen, LLC | 993.1K | 1.0% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | 4.8M | 1.4M | -3.4M |
| PRICE T ROWE ASSOCIATES INC /MD/ | Increased | 1.3M | 3.2M | +1.9M |
| BlackRock, Inc. | Increased | 5.6M | 7.5M | +1.9M |
| Holocene Advisors, LP | Sold Out | 1.5M | 0 | -1.5M |
| CITADEL ADVISORS LLC | Reduced | 2.7M | 1.4M | -1.3M |
| T. Rowe Price Investment Management, Inc. | Increased | 952.0K | 2.2M | +1.2M |
| FMR LLC | Reduced | 10.8M | 9.6M | -1.2M |
| JENNISON ASSOCIATES LLC | Reduced | 1.3M | 208.1K | -1.1M |
| TWO SIGMA INVESTMENTS, LP | Increased | 606.1K | 1.6M | +1.0M |
| Invesco Ltd. | Increased | 59.1K | 903.5K | +844.4K |
| Commodore Capital LP | Sold Out | 825.0K | 0 | -825.0K |
| Nuveen, LLC | Increased | 250.0K | 993.1K | +743.1K |
| JPMORGAN CHASE & CO | Increased | 1.9M | 2.6M | +693.8K |
| MARSHALL WACE, LLP | New | 0 | 689.3K | +689.3K |
| PANAGORA ASSET MANAGEMENT INC | New | 0 | 664.0K | +664.0K |
| Alyeska Investment Group, L.P. | Reduced | 1.3M | 697.7K | -601.8K |
| MPM BIOIMPACT LLC | Sold Out | 588.7K | 0 | -588.7K |
| Pictet Asset Management Holding SA | Increased | 679.7K | 1.2M | +508.0K |
| Caligan Partners LP | Reduced | 1.4M | 889.9K | -503.1K |
| Jones Hill Capital LP | New | 0 | 367.9K | +367.9K |
| Capital International Investors | Reduced | 2.7M | 2.4M | -313.1K |
| Man Group plc | New | 0 | 310.6K | +310.6K |
| Sofinnova Investments, Inc. | Sold Out | 305.2K | 0 | -305.2K |
| Fiera Capital Corp | Reduced | 709.5K | 405.6K | -303.9K |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 1.1M | 1.4M | +277.2K |
| STATE STREET CORP | Increased | 1.7M | 2.0M | +249.1K |
| AMERIPRISE FINANCIAL INC | Increased | 78.9K | 318.5K | +239.6K |
| BARCLAYS PLC | Reduced | 238.2K | 20.0K | -218.2K |
| BRAIDWELL LP | Reduced | 1.3M | 1.1M | -207.0K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Increased | 543.1K | 749.7K | +206.6K |
| STEMPOINT CAPITAL LP | Reduced | 281.5K | 76.1K | -205.4K |
| AMERICAN CENTURY COMPANIES INC | Increased | 679.3K | 884.3K | +205.0K |
| D. E. Shaw & Co., Inc. | Increased | 18.9K | 223.9K | +205.0K |
| Aberdeen Group plc | Reduced | 609.9K | 408.7K | -201.2K |
| First Turn Management, LLC | Reduced | 786.8K | 600.2K | -186.6K |
| MILLENNIUM MANAGEMENT LLC | Increased | 201.8K | 376.8K | +175.0K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | 470.0K | 300.0K | -170.0K |
| ORBIMED ADVISORS LLC | Reduced | 1.1M | 892.5K | -167.5K |
| Polar Capital Holdings Plc | Increased | 4.4M | 4.6M | +165.2K |
| ALLIANCEBERNSTEIN L.P. | Increased | 1.4M | 1.6M | +159.0K |
| FRANKLIN RESOURCES INC | Increased | 1.3M | 1.4M | +157.1K |
| ALGERT GLOBAL LLC | Increased | 264.2K | 419.8K | +155.6K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | 177.1K | 22.3K | -154.9K |
| Nicholas Investment Partners, LP | Increased | 247.1K | 395.8K | +148.7K |
| NORTHERN TRUST CORP | Increased | 527.8K | 671.6K | +143.8K |
| BANK OF AMERICA CORP /DE/ | Increased | 265.3K | 404.1K | +138.8K |
| Trexquant Investment LP | Increased | 67.4K | 202.5K | +135.1K |
| Point72 Asset Management, L.P. | New | 0 | 130.4K | +130.4K |
| Susquehanna Portfolio Strategies, LLC | Increased | 18.5K | 133.1K | +114.6K |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | 300.5K | 187.1K | -113.4K |
| Squarepoint Ops LLC | New | 0 | 112.9K | +112.9K |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Increased | 1.4M | 1.5M | +105.8K |
| Jump Financial, LLC | Increased | 155.8K | 260.7K | +105.0K |
| Parkman Healthcare Partners LLC | Reduced | 497.0K | 397.4K | -99.7K |
| Schonfeld Strategic Advisors LLC | Reduced | 324.7K | 227.3K | -97.4K |
| TimesSquare Capital Management, LLC | Increased | 359.3K | 451.6K | +92.3K |
| ExodusPoint Capital Management, LP | Reduced | 173.4K | 84.6K | -88.8K |
| FEDERATED HERMES, INC. | Reduced | 972.2K | 883.7K | -88.5K |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | 270.4K | 183.3K | -87.1K |
| HRT FINANCIAL LP | New | 0 | 86.5K | +86.5K |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.