XENE Xenon Pharmaceuticals Inc.

NASDAQ
$58.65

Xenon Pharmaceuticals Inc. (XENE) Hedge Fund Activity

This view isolates hedge funds from the broader institutional ownership shown on the Institutional tab. A pension fund tracking an index may have no view on a stock; when a hedge fund builds or exits a position, that decision can carry information. This page measures those changes. Positions as of June 30, 2026.

Based on quarterly 13F long-equity filings. Changes compare reported quarter-end positions; filings can be reported up to 45 days later and do not represent a fund's complete exposure.

Hedge fund breadth
-17.07
17 buyers / 24 sellers
SELLING
Funds compared
47
funds with comparable XENE positions
43 current holders · 39 prior-quarter holders
Net share change
-2.19M
+3.15M added, -5.34M cut
Position activity
8 new 9 increased 20 reduced 4 exited

Most significant moves

Ranked by conviction, not size — how much of the fund's own book the position represents, how far it moved, and what kind of fund made it.

Fund Action Shares changed Change Est. value Portfolio wt. Score
Caligan Partners Activist Event Reduced -503.1K -36.1% $30.4M 2.6% 69
Holocene Advisors, LP Sold Out -1.52M -100.0% $91.7M 0.0% 63
Point72 Asset Management, L.P. New +130.4K — $7.9M 0.0% 61
MARSHALL WACE, LLP Long/Short New +689.3K — $41.6M 0.1% 60
TWO SIGMA INVESTMENTS, LP Quant Increased +1.04M +171.1% $62.6M 0.1% 57
Qube Research & Technologies Ltd Quant Sold Out -44.0K -100.0% $2.7M 0.0% 57
Squarepoint Ops LLC Quant New +112.9K — $6.8M 0.0% 57
Magnetar Capital Event Quant New +18.2K — $1.1M 0.0% 57
Man Group Event Long/Short New +310.6K — $18.7M 0.0% 56
D. E. Shaw & Co., Inc. Quant Increased +205.0K +1082.3% $12.4M 0.0% 56

Most significant buyers

By move score, not size.

  • Point72 Asset Management, L.P. New · +130.4K
  • MARSHALL WACE, LLP New · +689.3K
  • TWO SIGMA INVESTMENTS, LP Increased · +1.04M
  • Squarepoint Ops LLC New · +112.9K
  • Magnetar Capital New · +18.2K

Most significant sellers

By move score, not size.

  • Caligan Partners Reduced · -503.1K
  • Holocene Advisors, LP Sold Out · -1.52M
  • Qube Research & Technologies Ltd Sold Out · -44.0K
  • LMR Partners Sold Out · -56.2K
  • Affinity Asset Advisors Reduced · -80.0K

Hedge fund positions

Fund Tier Shares Previous Change Change % Portfolio wt. Action Score
Caligan Partners 2 889.9K 1.4M -503.1K -36.1% 2.6% Reduced 69
Holocene Advisors, LP 2 0 1.5M -1.52M -100.0% 0.0% Sold Out 63
Point72 Asset Management, L.P. 1 130.4K 0 +130.4K — 0.0% New 61
MARSHALL WACE, LLP 2 689.3K 0 +689.3K — 0.1% New 60
TWO SIGMA INVESTMENTS, LP 2 1.6M 606.1K +1.04M +171.1% 0.1% Increased 57
Qube Research & Technologies Ltd 2 0 44.0K -44.0K -100.0% 0.0% Sold Out 57
Squarepoint Ops LLC 2 112.9K 0 +112.9K — 0.0% New 57
Magnetar Capital 2 18.2K 0 +18.2K — 0.0% New 57
Man Group 3 310.6K 0 +310.6K — 0.0% New 56
D. E. Shaw & Co., Inc. 1 223.9K 18.9K +205.0K +1082.3% 0.0% Increased 56
LMR Partners 3 0 56.2K -56.2K -100.0% 0.0% Sold Out 55
Capital Fund Management 3 84.5K 0 +84.5K — 0.0% New 55
Walleye Capital 3 77.0K 0 +77.0K — 0.0% New 53
Capstone Investment Advisors 3 8.9K 0 +8.9K — 0.0% New 53
Affinity Asset Advisors 2 1.6M 1.7M -80.0K -4.8% 4.8% Reduced 52
MILLENNIUM MANAGEMENT LLC 2 376.8K 201.8K +175.0K +86.7% 0.0% Increased 52
Y-Intercept 4 0 85.4K -85.4K -100.0% 0.0% Sold Out 51
Braidwell 2 1.1M 1.3M -207.0K -15.5% 2.7% Reduced 48
Trexquant Investment 3 202.5K 67.4K +135.1K +200.6% 0.1% Increased 47
CITADEL ADVISORS LLC 1 1.4M 2.7M -1.25M -47.2% 0.1% Reduced 45
Engineers Gate 4 62.2K 9.3K +52.9K +566.8% 0.0% Increased 44
Alyeska Investment Group, L.P. 2 697.7K 1.3M -601.8K -46.3% 0.1% Reduced 42
OrbiMed Advisors 2 892.5K 1.1M -167.5K -15.8% 1.0% Reduced 41
Rock Springs Capital Management 3 683.9K 763.0K -79.1K -10.4% 2.0% Reduced 40
Quantbot Technologies 4 947 162 +785 +484.6% 0.0% Increased 39
RENAISSANCE TECHNOLOGIES LLC 1 187.1K 300.5K -113.4K -37.7% 0.0% Reduced 39
ADAGE CAPITAL PARTNERS GP, L.L.C. 2 300.0K 470.0K -170.0K -36.2% 0.0% Reduced 38
Vestal Point Capital 1 700.0K 639.9K +60.1K +9.4% 1.0% Increased 37
ExodusPoint Capital Management 3 84.6K 173.4K -88.8K -51.2% 0.0% Reduced 37
ADAR1 Capital Management 3 166.6K 228.9K -62.3K -27.2% 0.5% Reduced 35
Soleus Capital Management 2 267.0K 292.0K -25.0K -8.6% 0.6% Reduced 33
Balyasny Asset Management L.P. 2 193.4K 233.9K -40.5K -17.3% 0.0% Reduced 33
Aquatic Capital Management 4 38.3K 79.2K -40.9K -51.6% 0.1% Reduced 33
Hudson Bay Capital Management 3 8.8K 14.1K -5.3K -37.7% 0.0% Reduced 32
Schonfeld Strategic Advisors 3 227.3K 324.7K -97.4K -30.0% 0.1% Reduced 30
Verition Fund Management 2 40.0K 55.0K -15.0K -27.3% 0.0% Reduced 30
Boothbay Fund Management 4 183.3K 270.4K -87.1K -32.2% 0.2% Reduced 30
Tudor Investment Corporation 2 545.4K 495.6K +49.8K +10.0% 0.2% Increased 28
Woodline Partners LP 2 155.3K 150.3K +5.0K +3.3% 0.0% Increased 24
Brevan Howard Capital Management 3 9.9K 12.0K -2.1K -17.4% 0.0% Reduced 23
AQR Capital Management 3 7.3K 7.3K -16 -0.2% 0.0% Reduced 20
Avoro Capital Advisors 1 5.8M 5.8M 0 +0.0% 3.1% Unchanged 41
Deerfield Management 1 1.6M 1.6M 0 +0.0% 1.2% Unchanged 31
Logos Global Management 2 450.0K 450.0K 0 +0.0% 1.2% Unchanged 26
Baker Bros. Advisors 1 370.2K 370.2K 0 +0.0% 0.1% Unchanged 26
Integral Health Asset Management 2 200.0K 200.0K 0 +0.0% 0.5% Unchanged 23
Palo Alto Investors 2 51.3K 51.3K 0 +0.0% 0.4% Unchanged 22

Every fund above opens. Subscribers can see any manager's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.

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Hedge funds are identified from their 13F filings, which are due 45 days after quarter end and cover long U.S.-listed equity positions only. A fund's short book never appears, so a reduced position can mean a changed view or a changed hedge — the filing doesn't say which.