ZYME Zymeworks Inc.

NASDAQ
$27.47

Zymeworks Inc. (ZYME) Institutional Ownership

What the institutions did with ZYME last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.

Managers reporting
229
filed a 13F this quarter
Managers holding
200
-6 on the quarter
Buyers
83
23 opened new
Sellers
102
29 sold out entirely
Buyer share
44.9%
of managers who traded it
Breadth
-10.3
net buyers, as a share of those trading

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Largest holders

Manager Shares % of reported
EcoR1 Capital, LLC 23.0M 33.0%
Rubric Capital Management LP 7.0M 10.1%
BlackRock, Inc. 4.3M 6.1%
PERCEPTIVE ADVISORS LLC 4.2M 6.0%
BVF INC/IL 3.6M 5.2%
Assenagon Asset Management S.A. 2.5M 3.6%
MORGAN STANLEY 2.2M 3.2%
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 1.8M 2.6%
VANGUARD CAPITAL MANAGEMENT LLC 1.6M 2.2%
Nextech Invest, Ltd. 1.1M 1.6%
STATE STREET CORP 1.1M 1.6%
DIMENSIONAL FUND ADVISORS LP 995.0K 1.4%
CITADEL ADVISORS LLC 914.1K 1.3%
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 889.8K 1.3%
FMR LLC 702.6K 1.0%
GEODE CAPITAL MANAGEMENT, LLC 692.4K 1.0%
Prosight Management, LP 674.4K 1.0%
Qube Research & Technologies Ltd 593.6K 0.9%
VANGUARD PORTFOLIO MANAGEMENT LLC 510.0K 0.7%
Redmile Group, LLC 491.7K 0.7%
Capricorn Fund Managers Ltd 486.5K 0.7%
GOLDMAN SACHS GROUP INC 470.8K 0.7%
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 418.5K 0.6%
DEUTSCHE BANK AG\ 397.2K 0.6%
Hillsdale Investment Management Inc. 382.9K 0.6%

Largest changes

Manager Action Previous Current Change
Assenagon Asset Management S.A. Increased 728.0K 2.5M +1.8M
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. New 0 889.8K +889.8K
PERCEPTIVE ADVISORS LLC Increased 3.5M 4.2M +672.9K
MPM BIOIMPACT LLC Sold Out 565.2K 0 -565.2K
Nuveen, LLC Reduced 651.7K 119.4K -532.3K
DEUTSCHE BANK AG\ Reduced 921.3K 397.2K -524.1K
Capricorn Fund Managers Ltd Reduced 1.0M 486.5K -520.7K
FIRST TRUST ADVISORS LP New 0 340.4K +340.4K
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP Reduced 743.9K 418.5K -325.4K
BlackRock, Inc. Reduced 4.6M 4.3M -302.9K
ROYCE & ASSOCIATES LP Sold Out 299.2K 0 -299.2K
Pictet Asset Management Holding SA Increased 9.3K 308.2K +298.9K
MORGAN STANLEY Reduced 2.5M 2.2M -249.3K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Reduced 319.4K 81.4K -238.0K
HRT FINANCIAL LP Sold Out 237.9K 0 -237.9K
CITADEL ADVISORS LLC Reduced 1.2M 914.1K -235.9K
JANE STREET GROUP, LLC Reduced 227.0K 17.4K -209.5K
VANGUARD CAPITAL MANAGEMENT LLC Reduced 1.7M 1.6M -146.6K
DIMENSIONAL FUND ADVISORS LP Reduced 1.1M 995.0K -144.2K
Prosight Management, LP Increased 539.0K 674.4K +135.4K
GOLDMAN SACHS GROUP INC Reduced 599.5K 470.8K -128.7K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. Reduced 1.9M 1.8M -126.9K
SummitTX Capital, L.P. Reduced 321.4K 210.8K -110.6K
D. E. Shaw & Co., Inc. Reduced 235.6K 144.8K -90.8K
STATE OF WISCONSIN INVESTMENT BOARD Increased 66.1K 155.6K +89.5K

13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.