IONS Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. (IONS) Institutional Ownership
What the institutions did with IONS last quarter, from their 13F filings. Counting managers rather than shares is the point: a single index fund adding to a position tells you far less than four hundred separate managers all deciding to. Positions as reported for the quarter ended June 30, 2026.
Every manager below opens. Subscribers can see any firm's whole portfolio — every position, its weight, and what they bought, trimmed and exited last quarter.
Sign in or subscribeLargest holders
| Manager | Shares | % of reported |
|---|---|---|
| FMR LLC | 24.6M | 13.7% |
| Capital World Investors | 21.7M | 12.1% |
| BlackRock, Inc. | 10.7M | 6.0% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 7.9M | 4.4% |
| WELLINGTON MANAGEMENT GROUP LLP | 7.7M | 4.3% |
| VANGUARD CAPITAL MANAGEMENT LLC | 7.2M | 4.0% |
| TWO SIGMA INVESTMENTS, LP | 6.3M | 3.5% |
| ROYAL BANK OF CANADA | 6.2M | 3.4% |
| STATE STREET CORP | 4.3M | 2.4% |
| T. Rowe Price Investment Management, Inc. | 4.0M | 2.2% |
| GEODE CAPITAL MANAGEMENT, LLC | 3.6M | 2.0% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.2M | 1.8% |
| JPMORGAN CHASE & CO | 2.7M | 1.5% |
| Artisan Partners Limited Partnership | 2.6M | 1.5% |
| Tweedy, Browne Co LLC | 2.3M | 1.3% |
| Deep Track Capital, LP | 2.2M | 1.2% |
| GOLDMAN SACHS GROUP INC | 2.1M | 1.2% |
| BAKER BROS. ADVISORS LP | 2.0M | 1.1% |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 2.0M | 1.1% |
| AMERICAN CENTURY COMPANIES INC | 1.9M | 1.1% |
| FRANKLIN RESOURCES INC | 1.6M | 0.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.6M | 0.9% |
| BARCLAYS PLC | 1.6M | 0.9% |
| Pictet Asset Management Holding SA | 1.6M | 0.9% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1.5M | 0.8% |
Largest changes
| Manager | Action | Previous | Current | Change |
|---|---|---|---|---|
| ROYAL BANK OF CANADA | Increased | 3.8M | 6.2M | +2.4M |
| T. Rowe Price Investment Management, Inc. | Reduced | 6.2M | 4.0M | -2.2M |
| BARCLAYS PLC | Increased | 289.9K | 1.6M | +1.3M |
| WELLINGTON MANAGEMENT GROUP LLP | Increased | 6.4M | 7.7M | +1.3M |
| Alyeska Investment Group, L.P. | Increased | 473.2K | 1.4M | +944.8K |
| Bellevue Group AG | Reduced | 1.8M | 972.3K | -846.4K |
| Capital International Investors | New | 0 | 823.8K | +823.8K |
| MILLENNIUM MANAGEMENT LLC | Reduced | 1.1M | 288.9K | -762.6K |
| CITADEL ADVISORS LLC | Reduced | 942.5K | 236.3K | -706.3K |
| Polar Capital Holdings Plc | Increased | 829.5K | 1.5M | +624.5K |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | Reduced | 1.4M | 787.3K | -616.8K |
| AMERIPRISE FINANCIAL INC | Reduced | 660.1K | 67.7K | -592.4K |
| Squarepoint Ops LLC | Reduced | 695.3K | 109.4K | -585.9K |
| Artisan Partners Limited Partnership | Increased | 2.1M | 2.6M | +581.7K |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | Increased | 785.3K | 1.3M | +515.1K |
| Capital World Investors | Increased | 21.2M | 21.7M | +482.9K |
| Davern Capital Partners, LP | Increased | 386.9K | 798.7K | +411.8K |
| GOLDMAN SACHS GROUP INC | Increased | 1.7M | 2.1M | +410.1K |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | 4.0M | 3.6M | -400.3K |
| TWO SIGMA INVESTMENTS, LP | Increased | 5.9M | 6.3M | +394.7K |
| Freestone Grove Partners LP | New | 0 | 340.0K | +340.0K |
| STATE STREET CORP | Increased | 4.0M | 4.3M | +339.3K |
| TimesSquare Capital Management, LLC | Increased | 275.7K | 614.1K | +338.4K |
| JANE STREET GROUP, LLC | Increased | 191.8K | 503.6K | +311.8K |
| JPMORGAN CHASE & CO | Increased | 2.4M | 2.7M | +308.2K |
13F filings are due 45 days after quarter end and cover long positions in U.S.-listed equities only, so this is a lagged and partial picture: shorts, bonds and foreign listings never appear. Options positions are excluded here rather than folded into the share counts. Political ownership is coming.