IONS Ionis Pharmaceuticals, Inc.

NASDAQ
$51.44

Ionis Pharmaceuticals, Inc. (IONS) Insider Activity

What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.

30D 90D 6M 1Y
Insider signal Subdued Selling ran below IONS's own trailing one-year pace, with 100% of sale value under a prearranged plan.
Cluster activity 0 buyers in the last 30 days 1 buyer in the last 90 days 9 sellers in the last 90 days
Insiders buying
1
2 transactions
Insiders selling
9
13 transactions
Purchases
$1.1M
20,000 shares
Sales
$14.0M
173,470 shares
Net activity
-$13.0M
purchases less sales

How much of that selling was preplanned? 100% planned / 0% discretionary

10b5-1 plan sales $14.0M 13 transactions · 173,470 shares
Discretionary sales $0 0 transactions · 0 shares

Largest single sale: $4.0M.

Where they traded

Buy Sell Dot area is proportional to transaction value.

Last open-market purchase: July 31, 2026 , by Hayden Michael R .

Recent open-market activity

Date Insider Role Action Shares Price Value Held after
Hayden Michael R Director Buy 5,000 $51.60 $258.0K 24,000
Hayden Michael R Director Buy 15,000 $53.38 $800.7K 19,000
BENNETT C FRANK 2 fills EVP, Chief Scientific Officer Sell 10b5-1 20,536 $84.95 $1.7M 75,018 −21.5% of holding
Diaz Allene M. Director Sell 10b5-1 10,111 $85.42 $863.6K 3,811 −72.6% of holding
Kordasiewicz Holly B. EVP, Chief Development Officer Sell 10b5-1 362 $84.30 $30.5K 22,096 −1.6% of holding
KLEIN JOSEPH III 2 fills Director Sell 10b5-1 11,518 $79.04 $910.4K 22,433 −33.9% of holding
Monia Brett P Chief Executive Officer Sell 10b5-1 50,000 $80.59 $4.0M 245,571 −16.9% of holding
Schneider Eugene EVP, Chf Clinical Develop Ofcr Sell 10b5-1 26,000 $81.05 $2.1M 77,114 −25.2% of holding
Baroldi Joseph EVP, Chief Business Officer Sell 10b5-1 5,635 $80.16 $451.7K 4,669 −54.7% of holding
O'NEIL PATRICK R. EVP CLO & General Counsel Sell 10b5-1 3,069 $80.00 $245.5K 61,470 −4.8% of holding
Monia Brett P Chief Executive Officer Sell 10b5-1 21,072 $78.49 $1.7M 245,571 −7.9% of holding
Swayze Eric EVP Research Sell 10b5-1 10,602 $79.18 $839.5K 21,759 −32.8% of holding
Monia Brett P Chief Executive Officer Sell 10b5-1 14,565 $78.41 $1.1M 245,571 −5.6% of holding

Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.