KYMR Kymera Therapeutics, Inc.

NASDAQ
$114.63

Kymera Therapeutics, Inc. (KYMR) Insider Activity

What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.

Insider signal Bearish Selling ran elevated versus KYMR's own trailing one-year pace, with 56% of sale value under a prearranged plan.
Cluster activity 0 buyers in the last 30 days 0 buyers in the last 90 days 6 sellers in the last 90 days
Insiders buying
0
0 transactions
Insiders selling
6
162 transactions
Purchases
$0
0 shares
Sales
$395.2M
3,670,650 shares
Net activity
-$395.2M
purchases less sales

How much of that selling was preplanned? 56% planned / 44% discretionary

10b5-1 plan sales $220.8M 155 transactions · 2,033,621 shares
Discretionary sales $174.4M 7 transactions · 1,637,029 shares

Largest single sale: $89.2M.

Where they traded

Buy Sell Dot area is proportional to transaction value.

Last open-market purchase: December 11, 2025 .

Recent open-market activity

Date Insider Role Action Shares Price Value Held after
Adams Brian 3 fills Chief Legal Officer Sell 6,371 $116.83 $744.3K 55,416 −10.3% of holding
Mainolfi Nello Chief Executive Officer Sell 10b5-1 50,000 $119.00 $6.0M 666,568 −7% of holding
Mainolfi Nello 5 fills Chief Executive Officer Sell 10b5-1 80,000 $115.29 $9.2M 744,685 −9.7% of holding
Goodman Noah Chief Business Officer Sell 10b5-1 3,389 $114.29 $387.3K 47,179 −6.7% of holding
Jacobs Bruce N. 8 fills Chief Financial Officer Sell 10b5-1 77,109 $114.96 $8.9M 320,492 −19.4% of holding
Booth Bruce 28 fills Director Sell 10b5-1 153,300 $108.05 $16.6M 2,446,453 −5.9% of holding
4 fills Sell 1,630,658 $106.50 $173.7M 1,960,881 −45.4% of holding
Booth Bruce 24 fills Director Sell 10b5-1 467,878 $110.29 $51.6M 2,834,055 −14.2% of holding
Booth Bruce 46 fills Director Sell 10b5-1 548,321 $118.76 $65.1M 3,333,349 −14.1% of holding
Goodman Noah 2 fills Chief Business Officer Sell 10b5-1 5,000 $114.00 $570.0K 52,695 −8.7% of holding
Booth Bruce 4 fills Director Sell 10b5-1 134,720 $100.51 $13.5M 3,357,833 −3.9% of holding
Booth Bruce 2 fills Director Sell 10b5-1 1,408 $99.98 $140.8K 3,461,521 −0% of holding
Booth Bruce 24 fills Director Sell 10b5-1 278,128 $99.12 $27.6M 3,691,811 −7% of holding
Goodman Noah Chief Business Officer Sell 10b5-1 2,500 $99.00 $247.5K 50,195 −4.7% of holding
Booth Bruce 6 fills Director Sell 10b5-1 115,056 $91.01 $10.5M 3,744,763 −3% of holding
Booth Bruce 3 fills Director Sell 10b5-1 116,812 $90.34 $10.6M 3,807,660 −3% of holding

Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.