KYMR Kymera Therapeutics, Inc.
$113.15
Kymera Therapeutics, Inc. (KYMR) Insider Activity
What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.
Insider signal
Bearish
Selling ran elevated versus KYMR's own trailing one-year pace, with 58% of sale value under a prearranged plan.
Cluster activity
0 buyers in the last 30 days
0 buyers in the last 90 days
6 sellers in the last 90 days
Insiders buying
0
0 transactions
Insiders selling
9
203 transactions
Purchases
$0
0 shares
Sales
$414.5M
3,907,507 shares
Net activity
-$414.5M
purchases less sales
How much of that selling was preplanned? 58% planned / 42% discretionary
10b5-1 plan sales
$239.3M
192 transactions · 2,260,660 shares
Discretionary sales
$175.2M
11 transactions · 1,646,847 shares
Largest single sale: $89.2M.
Where they traded
Buy
Sell
Dot area is proportional to transaction value.
Last open-market purchase: December 11, 2025 .
Recent open-market activity
| Date | Insider | Role | Action | Shares | Price | Value | Held after |
|---|---|---|---|---|---|---|---|
| Adams Brian 3 fills | Chief Legal Officer | Sell | 6,371 | $116.83 | $744.3K | 55,416 −10.3% of holding | |
| Mainolfi Nello | Chief Executive Officer | Sell 10b5-1 | 50,000 | $119.00 | $6.0M | 666,568 −7% of holding | |
| Mainolfi Nello 5 fills | Chief Executive Officer | Sell 10b5-1 | 80,000 | $115.29 | $9.2M | 744,685 −9.7% of holding | |
| Goodman Noah | Chief Business Officer | Sell 10b5-1 | 3,389 | $114.29 | $387.3K | 47,179 −6.7% of holding | |
| Jacobs Bruce N. 8 fills | Chief Financial Officer | Sell 10b5-1 | 77,109 | $114.96 | $8.9M | 320,492 −19.4% of holding | |
| Booth Bruce 28 fills | Director | Sell 10b5-1 | 153,300 | $108.05 | $16.6M | 2,446,453 −5.9% of holding | |
| 4 fills | Sell | 1,630,658 | $106.50 | $173.7M | 1,960,881 −45.4% of holding | ||
| Booth Bruce 24 fills | Director | Sell 10b5-1 | 467,878 | $110.29 | $51.6M | 2,834,055 −14.2% of holding | |
| Booth Bruce 46 fills | Director | Sell 10b5-1 | 548,321 | $118.76 | $65.1M | 3,333,349 −14.1% of holding | |
| Goodman Noah 2 fills | Chief Business Officer | Sell 10b5-1 | 5,000 | $114.00 | $570.0K | 52,695 −8.7% of holding | |
| Booth Bruce 4 fills | Director | Sell 10b5-1 | 134,720 | $100.51 | $13.5M | 3,357,833 −3.9% of holding | |
| Booth Bruce 2 fills | Director | Sell 10b5-1 | 1,408 | $99.98 | $140.8K | 3,461,521 −0% of holding | |
| Booth Bruce 24 fills | Director | Sell 10b5-1 | 278,128 | $99.12 | $27.6M | 3,691,811 −7% of holding | |
| Goodman Noah | Chief Business Officer | Sell 10b5-1 | 2,500 | $99.00 | $247.5K | 50,195 −4.7% of holding | |
| Booth Bruce 6 fills | Director | Sell 10b5-1 | 115,056 | $91.01 | $10.5M | 3,744,763 −3% of holding | |
| Booth Bruce 3 fills | Director | Sell 10b5-1 | 116,812 | $90.34 | $10.6M | 3,807,660 −3% of holding | |
| Chadwick Jeremy G 2 fills | Chief Operating Officer | Sell 10b5-1 | 4,279 | $81.58 | $349.1K | 44,618 −8.8% of holding | |
| Chadwick Jeremy G 3 fills | Chief Operating Officer | Sell 10b5-1 | 8,851 | $79.80 | $706.3K | 53,348 −14.2% of holding | |
| Chadwick Jeremy G 2 fills | Chief Operating Officer | Sell | 4,054 | $78.42 | $317.9K | 57,472 −6.6% of holding | |
| Ridloff Elena | Director | Sell 10b5-1 | 3,000 | $87.00 | $261.0K | None left | |
| Mainolfi Nello 3 fills | Chief Executive Officer | Sell 10b5-1 | 30,000 | $81.18 | $2.4M | 679,190 −4.2% of holding | |
| Booth Bruce 3 fills | Director | Sell 10b5-1 | 6,000 | $89.96 | $539.8K | 3,899,829 −0.2% of holding | |
| Chadwick Jeremy G | Chief Operating Officer | Sell 10b5-1 | 300 | $90.00 | $27.0K | 61,202 −0.5% of holding | |
| Booth Bruce 3 fills | Director | Sell 10b5-1 | 5,335 | $90.04 | $480.4K | 3,899,917 −0.1% of holding | |
| Chadwick Jeremy G | Chief Operating Officer | Sell 10b5-1 | 1,300 | $90.00 | $117.0K | 61,202 −2.1% of holding | |
| Chadwick Jeremy G | Chief Operating Officer | Sell 10b5-1 | 5,251 | $90.00 | $472.6K | 61,202 −7.9% of holding | |
| Booth Bruce | Director | Sell 10b5-1 | 4,159 | $89.97 | $374.2K | None left | |
| Goodman Noah | Chief Business Officer | Sell 10b5-1 | 1,347 | $90.00 | $121.2K | 50,195 −2.6% of holding | |
| Goodman Noah | Chief Business Officer | Sell 10b5-1 | 2,000 | $87.35 | $174.7K | 51,542 −3.7% of holding | |
| Goodman Noah 2 fills | Chief Business Officer | Sell | 5,764 | $86.85 | $500.6K | 58,712 −8.9% of holding | |
| Goodman Noah | Chief Business Officer | Sell 10b5-1 | 2,500 | $89.00 | $222.5K | 53,542 −4.5% of holding | |
| Chadwick Jeremy G 2 fills | Chief Operating Officer | Sell 10b5-1 | 14,640 | $85.46 | $1.3M | 62,302 −19% of holding | |
| Ridloff Elena 2 fills | Director | Sell 10b5-1 | 4,600 | $85.42 | $392.9K | 1,200 −79.3% of holding | |
| Chadwick Jeremy G | Chief Operating Officer | Sell 10b5-1 | 7,600 | $85.38 | $648.9K | 61,202 −11% of holding | |
| Ridloff Elena | Director | Sell 10b5-1 | 7,400 | $85.37 | $631.7K | None left | |
| Chadwick Jeremy G | Chief Operating Officer | Sell 10b5-1 | 24,727 | $80.26 | $2.0M | 61,202 −28.8% of holding | |
| Chadwick Jeremy G 5 fills | Chief Operating Officer | Sell 10b5-1 | 91,250 | $77.41 | $7.1M | 129,696 −41.3% of holding | |
| Esposito Pamela 3 fills | Director | Sell 10b5-1 | 2,500 | $79.15 | $197.9K | 1,800 −58.1% of holding |
Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.