SYRE Spyre Therapeutics, Inc.
Spyre Therapeutics, Inc. (SYRE) Insider Activity
What the officers, directors and large holders did with their own shares. Only open-market purchases and sales count toward the totals — grants, option exercises and shares withheld for tax are compensation mechanics, not decisions, and they're listed separately below.
How much of that selling was preplanned? 3% planned / 97% discretionary
Largest single sale: $399.7M.
Where they traded
No open-market insider purchase on record.
Recent open-market activity
| Date | Insider | Role | Action | Shares | Price | Value | Held after |
|---|---|---|---|---|---|---|---|
| Burrows Scott L | Chief Financial Officer | Sell | 18,232 | $89.35 | $1.6M | 79,762 −18.6% of holding | |
| King-Jones Heidy | See Remarks | Sell 10b5-1 | 400 | $90.00 | $36.0K | 2,845 −12.3% of holding | |
| King-Jones Heidy 4 fills | See Remarks | Sell 10b5-1 | 27,999 | $87.31 | $2.4M | 25,999 −51.9% of holding | |
| Turtle Cameron 4 fills | Chief Executive Officer | Sell 10b5-1 | 15,000 | $87.29 | $1.3M | 565,040 −2.6% of holding | |
| Burrows Scott L 4 fills | Chief Financial Officer | Sell 10b5-1 | 7,500 | $87.31 | $654.8K | 104,594 −6.7% of holding | |
| Albers Jeffrey W. 3 fills | Director | Sell 10b5-1 | 23,000 | $104.53 | $2.4M | 19,360 −54.3% of holding | |
| Turtle Cameron 5 fills | Chief Executive Officer | Sell 10b5-1 | 15,000 | $95.51 | $1.4M | 581,740 −2.5% of holding | |
| Burrows Scott L 3 fills | Chief Financial Officer | Sell 10b5-1 | 7,500 | $95.57 | $716.8K | 100,394 −7% of holding | |
| Turtle Cameron 3 fills | Chief Executive Officer | Sell 10b5-1 | 15,000 | $87.69 | $1.3M | 587,364 −2.5% of holding | |
| Sloan Sheldon 2 fills | Chief Medical Officer | Sell 10b5-1 | 8,334 | $87.70 | $730.9K | 1,834 −82% of holding | |
| Burrows Scott L 2 fills | Chief Financial Officer | Sell 10b5-1 | 7,500 | $87.74 | $658.0K | 99,719 −7% of holding | |
| Burrows Scott L 2 fills | Chief Financial Officer | Sell | 15,000 | $87.13 | $1.3M | 107,994 −12.2% of holding | |
| Sell | 4,684,781 | $85.31 | $399.7M | None left | |||
| HENDERSON MICHAEL THOMAS | Director | Sell 10b5-1 | 20,000 | $100.00 | $2.0M | 68,606 −22.6% of holding |
Form 4s are due within two business days of a transaction, so this is close to real time — unlike the quarterly 13F data on the Institutional tab. A single large sale often reflects a prearranged 10b5-1 plan rather than a fresh view, so read a pattern of sales rather than any one of them.